Use of a Novel Peripheral Biomarker, Urine Trans, Trans, Muconic Acid, for Benzene Toxicity Monitoring

2004 ◽  
Vol 23 (4) ◽  
pp. 467-475 ◽  
Author(s):  
Viroj Wiwanitkit
Keyword(s):  
Muconic Acid ◽  
Toxicity Monitoring ◽  
Peripheral Biomarker

scholarly journals Electrochemical hydrogenation of bioprivileged cis,cis-muconic acid to trans-3-hexenedioic acid: from lab synthesis to bench-scale production and beyond

2021 ◽  
Author(s):  
Marco Nazareno State Dell'Anna ◽  
Mathew Laureano ◽  
Hamed Bateni ◽  
John E Matthiesen ◽  
Ludovic Zaza ◽  
...  
Keyword(s):  
Scale Production ◽  
Electrochemical Hydrogenation ◽  
Muconic Acid ◽  
Hybrid Processes ◽  
Bench Scale

The integration of microbial and electrochemical conversions in hybrid processes broadens the portfolio of products accessible from biomass. For instance, sugars and lignin monomers can be biologically converted to cis,cis-muconic...

Covalent-coordination tandem functionalization of metal-organic framework (UiO-66) as a hybrid probe for luminescence detection of trans, trans-muconic acid as a biomarker of benzene and Fe3+

The Analyst ◽  
2021 ◽  
Author(s):  
Jie Min ◽  
Xiang-Long Qu ◽  
Bing Yan
Keyword(s):  
Hybrid Material ◽  
Metal Organic Framework ◽  
Luminescent Properties ◽  
Muconic Acid ◽  
Luminescence Detection ◽  
Metal Organic ◽  
Organic Framework

By means of post-synthetic treatment on the UiO-66 derivative with -SO3H, a novel luminescent hybrid material named Tb3+@UiO-66-SO3H has been prepared simply and efficiently. Given its wonderful luminescent properties like...

Muconic acid as high-performance organic anode for lithium ion batteries

2021 ◽  
Vol 865 ◽  
pp. 158573
Author(s):  
Jingshi Wang ◽  
Zhigang Shen ◽  
Min Yi ◽  
Xiaojing Zhang
Keyword(s):  
Lithium Ion Batteries ◽  
High Performance ◽  
Lithium Ion ◽  
Muconic Acid

scholarly journals Oxidation Reactions of Marchantin A Trimethyl Ether and Some Aromatic Compounds using m-Chloroperbenzoic Acid. Formation of Muconic Acid Ester and m-Chlorobenzoate

1999 ◽  
Vol 23 (8) ◽  
pp. 470-471
Author(s):  
Motoo Tori ◽  
Masakazu Sono ◽  
Keiko Takikawa ◽  
Reiko Matsuda ◽  
Masao Toyota ◽  
...  
Keyword(s):  
Aromatic Ring ◽  
Methyl Ether ◽  
Aromatic Compounds ◽  
Acid Ester ◽  
Acid Formation ◽  
Oxidation Reactions ◽  
Muconic Acid ◽  
Trimethyl Ether

On treatment with m-chloroperbenzoic acid, dihydroeugenol methyl ether and marchantin A trimethyl ether afford muconic acid ester derivatives by oxidation of the aromatic ring as well as hydroxylated derivatives; the m-chlorobenzoate of the dihydroeugenol derivative is also observed for the former.

scholarly journals Enzymatic Synthesis of Muconic Acid-Based Polymers: Trans, Trans-Dimethyl Muconate and Trans, β-Dimethyl Hydromuconate

Polymers ◽  
2021 ◽  
Vol 13 (15) ◽  
pp. 2498
Author(s):  
Dina Maniar ◽  
Csaba Fodor ◽  
Indra Karno Adi ◽  
Albert J. J. Woortman ◽  
Jur van Dijken ◽  
...  
Keyword(s):  
Reaction Mechanism ◽  
Renewable Resources ◽  
Enzymatic Synthesis ◽  
Enzyme Catalysis ◽  
Unsaturated Polyester ◽  
Chain Extension ◽  
Side Reactions ◽  
Muconic Acid ◽  
Thermal Stabilities ◽  
Polyester Resins

The vast majority of commodity polymers are acquired from petrochemical feedstock, and these resources will plausibly be depleted within the next 100 years. Therefore, the utilization of carbon-neutral renewable resources for the production of polymers is crucial in modern green chemistry. Herein, we report an eco-friendly strategy that uses enzyme catalysis to design biobased unsaturated (co)polyesters from muconic acid derivatives. This method is an attractive pathway for the production of well-defined unsaturated polyesters with minimum side reactions. A suite of characterization techniques was performed to probe the reaction mechanism and properties of the obtained polyesters. It is rationalized that the alkene functionality of the muconate monomers plays an important role in the enzyme catalysis mechanism. The rendered polyesters possessed excellent thermal stabilities and unreacted alkene functionality that can consecutively undergo chain extension, copolymerization, or act as an anchor for other functional groups. These properties open new avenues in the fields of unsaturated polyester resins and photosensitive coatings.

Telomere Length and Arsenic: Improving Animal Models of Toxicity by Choosing Mice With Shorter Telomeres

2021 ◽  
Vol 40 (3) ◽  
pp. 211-217
Author(s):  
Brayden Whitlock
Keyword(s):  
Animal Models ◽  
Telomere Length ◽  
Mouse Models ◽  
Arsenic Exposure ◽  
Tumor Formation ◽  
The Body ◽  
Cancer Resistance ◽  
Selective Pressures ◽  
Toxicity Monitoring ◽  
In Captivity

Arsenic is both a chemotherapeutic drug and an environmental toxicant that affects hundreds of millions of people each year. Arsenic exposure in drinking water has been called the worst poisoning in human history. How arsenic is handled in the body is frequently studied using rodent models to investigate how arsenic both causes and treats disease. These models, used in a variety of arsenic-related testing, from tumor formation to drug toxicity monitoring, have virtually always been developed from animals with telomeres that are unnaturally long, likely because of accidental artificial selective pressures. Mice that have been bred in captivity in laboratory conditions, often for over 100 years, are the standard in creating animal models for this research. Using these mice introduces challenges to any work that can be affected by the length of telomeres and the related capacities for tissue repair and cancer resistance. However, arsenic research is particularly susceptible to the misuse of such animal models due to the multiple and various interactions between arsenic and telomeres. Researchers in the field commonly find mouse models and humans behaving very differently upon exposure to acute and chronic arsenic, including drug therapies which seem safe in mice but are toxic in humans. Here, some complexities and apparent contradictions of the arsenic carcinogenicity and toxicity research are reconciled by an explanatory model that involves telomere length explained by the evolutionary pressures in laboratory mice. A low-risk hypothesis is proposed which has the power to determine whether researchers can easily develop more powerful and accurate mouse models by simply avoiding mouse lineages that are very old and have strangely long telomeres. Swapping in newer mouse lineages for the older, long-telomere mice may vastly improve our ability to research arsenic toxicity with virtually no increase in cost or difficulty of research.

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