Treatment Persistence with Leukotriene Receptor Antagonists and Inhaled Corticosteroids

2005 ◽  
Vol 42 (5) ◽  
pp. 385-393 ◽  
Author(s):  
Marc Dorais ◽  
Lucie Blais ◽  
Isabelle Chabot ◽  
Jacques LeLorier
Keyword(s):  
Inhaled Corticosteroids ◽  
Receptor Antagonists ◽  
Treatment Persistence ◽  
Leukotriene Receptor Antagonists ◽  
Leukotriene Receptor

scholarly journals Introduction of Leukotriene Receptor Antagonists in Manitoba

2006 ◽  
Vol 13 (2) ◽  
pp. 94-98 ◽  
Author(s):  
C Macie ◽  
K Wooldrage ◽  
J Manfreda ◽  
NR Anthonisen
Keyword(s):  
Inhaled Corticosteroids ◽  
Patient Characteristics ◽  
Prescribing Patterns ◽  
Chronic Obstructive ◽  
Receptor Antagonists ◽  
Obstructive Pulmonary Disease ◽  
Physician Visits ◽  
Leukotriene Receptor Antagonists ◽  
Leukotriene Receptor ◽  
Health Database

Patient characteristics and prescribing patterns during the introduction of leukotriene receptor antagonists (LTRA) in Manitoba are described using the provincial health database. Residents of Manitoba with asthma, chronic obstructive pulmonary disease, bronchitis or claims for respiratory medications were identified. Six thousand forty-one of 160,626 (3.8%) patients received LTRA; the likelihood of receiving LTRA increased if a patient was younger than 15 years, lived in a rural locale, had asthma, had frequent physician visits or used inhaled corticosteroids. Subsequent prescriptions (68%) were associated with the number of physician visits and inhaled corticosteroid use, which were thought to be indexes of severity. Patients, especially children, who received more than five prescriptions showed evidence of increased asthma control, but there was little evidence of benefit in less selected patient groups due, at least in part, to poor compliance with all respiratory drugs.

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