Nanotopography: Control Microbial Attachment to Surfaces

2010 ◽  
pp. 1-4
Author(s):  
Guoping Feng
Keyword(s):  
Microbial Attachment

scholarly journals Superhydrophobic Nanocoatings as Intervention against Biofilm-Associated Bacterial Infections

Nanomaterials ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 1046
Author(s):  
Yinghan Chan ◽  
Xun Hui Wu ◽  
Buong Woei Chieng ◽  
Nor Azowa Ibrahim ◽  
Yoon Yee Then
Keyword(s):  
Biofilm Formation ◽  
Bacterial Infections ◽  
Therapeutic Strategies ◽  
Public Healthcare ◽  
Persistent Infections ◽  
Promising Strategy ◽  
Antimicrobial Interventions ◽  
Novel Therapeutic Strategies ◽  
Insight Into ◽  
Microbial Attachment

Biofilm formation represents a significant cause of concern as it has been associated with increased morbidity and mortality, thereby imposing a huge burden on public healthcare system throughout the world. As biofilms are usually resistant to various conventional antimicrobial interventions, they may result in severe and persistent infections, which necessitates the development of novel therapeutic strategies to combat biofilm-based infections. Physicochemical modification of the biomaterials utilized in medical devices to mitigate initial microbial attachment has been proposed as a promising strategy in combating polymicrobial infections, as the adhesion of microorganisms is typically the first step for the formation of biofilms. For instance, superhydrophobic surfaces have been shown to possess substantial anti-biofilm properties attributed to the presence of nanostructures. In this article, we provide an insight into the mechanisms underlying biofilm formation and their composition, as well as the applications of nanomaterials as superhydrophobic nanocoatings for the development of novel anti-biofilm therapies.

scholarly journals The human IgG anti-carbohydrate repertoire exhibits a universal architecture and contains specificity for microbial attachment sites

2015 ◽  
Vol 7 (269) ◽  
pp. 269ra1-269ra1 ◽  
Author(s):  
C. Schneider ◽  
D. F. Smith ◽  
R. D. Cummings ◽  
K. F. Boligan ◽  
R. G. Hamilton ◽  
...  
Keyword(s):  
Human Igg ◽  
Attachment Sites ◽  
Microbial Attachment

scholarly journals Assessment of a weak mode of bacterial adhesion by applying an electric field

2020 ◽  
Author(s):  
George Araujo ◽  
Joy Zheng ◽  
Jae Jong Oh ◽  
Jay X. Tang
Keyword(s):  
Electric Field ◽  
Environmental Control ◽  
Caulobacter Crescentus ◽  
Surface Interaction ◽  
Bacterial Attachment ◽  
Stick Slip ◽  
Attached Bacteria ◽  
Plastic Surface ◽  
Unique Approach ◽  
Microbial Attachment

ABSTRACTMicrobial attachment to surfaces is ubiquitous in nature. Most species of bacteria attach and adhere to surfaces via special appendages such as pili and fimbriae, the roles of which have been extensively studied. Here we report an experiment on pilus-less mutants of Caulobacter crescentus weakly attached to a plastic surface and subjected to an electric field parallel to the surface. We find that some individual cells transiently but repeatedly adhere to the surface in a stick-slip fashion in the presence of an electric field. Even while transiently detached, these bacteria move significantly slower than the unattached ones in the same field of view undergoing electrophoretic motion. We refer this behavior of repeated and transient attachment as “quasi-attachment”. The speed of the quasi-attached bacteria exhibits large variations, frequently dropping close to zero for short intervals of time. This study suggests applying electric field as a useful method to investigate bacteria-surface interaction, which is significant in broader contexts such as infection and environmental control.SignificanceInteraction between bacteria and surfaces occur widely in nature, including those in industrial, environmental, and medical settings. It is therefore important to understand various mechanisms and factors that affect numerous forms of bacterium-surface interaction, particularly those resulting in adhesion or attachment, be they strong or weak, permanent or transient. This work takes a unique approach to identify a transient and reversible mode of bacterial attachment to a solid surface, by applying an electric field to exert a force for detachment. The force thus exerted proves to reach the amplitude required to detach bacteria of a pilus-less strain that weakly attach to a plastic surface. The method may be applied broadly to investigate bacteria-surface interaction.

EFFECTS OF RUMINAL EXPOSURE ON THE AMINO ACID PROFILE OF FEEDS

1987 ◽  
Vol 67 (4) ◽  
pp. 1143-1148 ◽  
Author(s):  
B. A. CROOKER ◽  
J. H. CLARK ◽  
R. D. SHANKS ◽  
G. C. FAHEY Jr.
Keyword(s):  
Amino Acid ◽  
Key Words ◽  
Microbial Contamination ◽  
Amino Acid Profile ◽  
Diaminopimelic Acid ◽  
Individual Amino Acid ◽  
Amino Acid Compositions ◽  
Ruminal Degradation ◽  
Key Words Amino Acid ◽  
Microbial Attachment

Seven feeds were individually incubated (12 h) in ruminally suspended polyester bags. Several alterations (P < 0.05) between individual amino acid compositions of feeds and their respective residues were detected after adjusting for microbial contamination of residues. Detection of diaminopimelic acid in feeds suggests that not all diaminopimelic acid in digesta originates from bacteria. Key words: Amino acid, ruminal degradation, microbial attachment, diaminopimelic acid

The influence of cell and substratum surface hydrophobicities on microbial attachment

2004 ◽  
Vol 110 (3) ◽  
pp. 251-256 ◽  
Author(s):  
Yu Liu ◽  
Shu-Fang Yang ◽  
Yong Li ◽  
Hui Xu ◽  
Lei Qin ◽  
...  
Keyword(s):  
Microbial Attachment
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