Nimesulide and β-Cyclodextrin Inclusion Complexes: Physicochemical Characterization and Dissolution Rate Studies

2000 ◽  
Vol 26 (11) ◽  
pp. 1217-1220 ◽  
Author(s):  
K. P. R. Chowdary ◽  
Buchi N. Nalluri
Keyword(s):  
Dissolution Rate ◽  
Inclusion Complexes ◽  
Physicochemical Characterization ◽  
Cyclodextrin Inclusion Complexes ◽  
Cyclodextrin Inclusion

scholarly journals Physicochemical characterization and in vitro dissolution behaviour of celecoxib-β-cyclodextrin inclusion complexes

2007 ◽  
Vol 57 (1) ◽  
pp. 47-60 ◽  
Author(s):  
Vivek Sinha ◽  
R. Anitha ◽  
Soma Ghosh ◽  
Rachana Kumria ◽  
Jayant Bhinge ◽  
...  
Keyword(s):  
Dissolution Rate ◽  
Inclusion Complexes ◽  
Physicochemical Characterization ◽  
Aqueous Solubility ◽  
In Vitro Dissolution ◽  
Cyclodextrin Inclusion Complexes ◽  
Cyclodextrin Inclusion ◽  
Dissolution Behaviour ◽  
Poorly Soluble

Physicochemical characterization and in vitro dissolution behaviour of celecoxib-β-cyclodextrin inclusion complexes In this study, attempts were made to investigate the effects of β-cyclodextrin (β-CD) on the aqueous solubility and dissolution rate of celecoxib. Inclusion complexes were prepared by the kneading method and characterized by SEM, NMR, IR, DSC, and X-ray powder diffraction. Dissolution rate of the complexes was significantly greater than that of the corresponding physical mixtures and pure drug, indicating that the formation of inclusion complex increased the solubility of the poorly soluble drug celecoxib.

Physicochemical characterization of cholesterol-beta cyclodextrin inclusion complexes

1991 ◽  
Vol 37 (11-12) ◽  
pp. 2497-2506 ◽  
Author(s):  
P. Cloudy ◽  
J. M. Létoffé ◽  
P. Germain ◽  
J. P. Bastide ◽  
A. Bayol ◽  
...  
Keyword(s):  
Inclusion Complexes ◽  
Physicochemical Characterization ◽  
Cyclodextrin Inclusion Complexes ◽  
Beta Cyclodextrin ◽  
Cyclodextrin Inclusion
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