Gemcitabine and Cisplatin in Advanced Nasopharyngeal Carcinoma: A Pilot Study

2005 ◽  
Vol 23 (2) ◽  
pp. 123-128 ◽  
Author(s):  
Yu Jiang ◽  
Yu-quan Wei ◽  
Feng Luo ◽  
Li-qun Zou ◽  
Ji-yan Liu ◽  
...  
Keyword(s):  
Pilot Study ◽  
Nasopharyngeal Carcinoma ◽  
Gemcitabine And Cisplatin

Transfer factor with anti-EBV activity as an adjuvant therapy for nasopharyngeal carcinoma: A pilot study

Biotherapy ◽  
1996 ◽  
Vol 9 (1-3) ◽  
pp. 109-115 ◽  
Author(s):  
Umapati Prasad ◽  
Mohd Amin bin Jalaludin ◽  
Pathmanathan Rajadurai ◽  
Giancarlo Pizza ◽  
Caterina De Vinci ◽  
...  
Keyword(s):  
Pilot Study ◽  
Nasopharyngeal Carcinoma ◽  
Adjuvant Therapy ◽  
Transfer Factor

scholarly journals Non-Gaussian Analysis of Diffusion Weighted Imaging in Head and Neck at 3T: A Pilot Study in Patients with Nasopharyngeal Carcinoma

PLoS ONE ◽  
2014 ◽  
Vol 9 (1) ◽  
pp. e87024 ◽  
Author(s):  
Jing Yuan ◽  
David Ka Wai Yeung ◽  
Greta S. P. Mok ◽  
Kunwar S. Bhatia ◽  
Yi-Xiang J. Wang ◽  
...  
Keyword(s):  
Pilot Study ◽  
Nasopharyngeal Carcinoma ◽  
Head And Neck ◽  
Diffusion Weighted Imaging ◽  
Diffusion Weighted ◽  
Gaussian Analysis ◽  
Non Gaussian

Office-Based Cricopharyngeus Balloon Dilation for Post Chemoirradiation Dysphagia in Nasopharyngeal Carcinoma Patients: A Pilot Study

Dysphagia ◽  
2019 ◽  
Vol 34 (4) ◽  
pp. 540-547 ◽  
Author(s):  
Raymond Fong ◽  
Nikie Sun ◽  
Yiu-Wing Ng ◽  
Anna F. Rumbach ◽  
Elizabeth C. Ward ◽  
...  
Keyword(s):  
Pilot Study ◽  
Nasopharyngeal Carcinoma ◽  
Balloon Dilation

scholarly journals A Pilot Study: N-Staging Assessment of Shear Wave Elastrography in Small Cervical Lymph Nodes for Nasopharyngeal Carcinoma

2020 ◽  
Vol 10 ◽  
Author(s):  
Ying Guan ◽  
Shuai Liu ◽  
An-Chuan Li ◽  
Xin-Bin Pan ◽  
Zhong-Guo Liang ◽  
...  
Keyword(s):  
Pilot Study ◽  
Nasopharyngeal Carcinoma ◽  
Lymph Nodes ◽  
Shear Wave ◽  
Cervical Lymph Nodes ◽  
N Staging

Induction gemcitabine cisplatin followed by chemoradiation in locally advanced nasopharyngeal cancer.

2017 ◽  
Vol 35 (15_suppl) ◽  
pp. 6027-6027 ◽  
Author(s):  
Sadaf Usman ◽  
Sara Rasheed ◽  
Ali Raza ◽  
Raza Hussain ◽  
Arif Jamshed
Keyword(s):  
Nasopharyngeal Carcinoma ◽  
Randomized Clinical Trials ◽  
Locally Advanced ◽  
Nasopharyngeal Cancer ◽  
Stage Iv ◽  
Attractive Alternative ◽  
Current Standard ◽  
Alternative Approach ◽  
Recent Addition ◽  
Gemcitabine And Cisplatin

6027 Background: The current standard of treatment in locally advanced nasopharyngeal cancer is concurrent chemoradiation, however recent addition of induction chemotherapy in the already established regimen has presented an attractive alternative approach. We report on survival with induction Gemcitabine and Cisplatin (GC) followed by chemoradiation (CRT) in the treatment of advanced nasopharyngeal carcinoma. Methods: Between 2005 and 2015, 300 patients (M 70%: F 30%) with histologically confirmed nasopharyngeal carcinoma. Histological subtypes WHO I 4% (13) and WHO III 96% (287). AJCC (7th edition) stage was Stage III 28% (85) and Stage IV 72% (215) patients. IC included a 2 drug combination; intravenous gemcitabine 1000 mg/m2 on day 1 and 8 and cisplatin 75 mg/m2 on day 1 only. Radiotherapy was given as a phase treatment to a total dose of 70 Gy in 35 fractions. Concurrent three weekly cisplatin (75 mg/m2) was administered to all patients. Results: Median follow up time was 30 months. The 5-year overall survival (OS), loco regional control (LRC) and relapse free survival (RFS) rates were 70% (95% CI 6.43 – 7.52), 69% (95% CI 6.52 – 7.64) and 52% (95% CI 5.25 – 6.34) respectively. One hundred and seven patients failed treatment; local or loco-regional 39% (42), regional 16% (17) and distant 45% (48). Conclusions: We conclude that induction gemcitabine and cisplatin followed by chemo-radiation is an effective regimen in management of nasopharyngeal carcinoma, meriting further investigation in randomized clinical trials.

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