Spectrofluorimetric Determination of Thiols in Biological Samples with a New Fluorescent Probe 3‐Maleimidylbenzanthrone

2005 ◽  
Vol 38 (5) ◽  
pp. 791-802 ◽  
Author(s):  
Ni‐Na Fu ◽  
Hong Wang ◽  
Meng‐Ling Li ◽  
Guo‐Jin Zheng ◽  
Hua‐Shan Zhang ◽  
...  
2015 ◽  
Vol 7 (22) ◽  
pp. 9609-9614 ◽  
Author(s):  
Mojtaba Shamsipur ◽  
Parvin Zohrabi ◽  
Mahdi Hashemi

The proposed method focuses on the application of a supramolecular solvent as the carrier for ferrofluid based microextraction coupled to spectrofluorimetry for the determination of levofloxacin in biological samples.


Author(s):  
Qing-Hao Liu ◽  
Xi-Long Yan ◽  
Jin-Chun Guo ◽  
Dong-Hua Wang ◽  
Lei Li ◽  
...  

1997 ◽  
Vol 30 (8) ◽  
pp. 1531-1539 ◽  
Author(s):  
Zuyun Huang ◽  
Ruxiu Cai ◽  
Ke Zhang ◽  
Houping Huang ◽  
Yune Zeng

2020 ◽  
Vol 7 (8) ◽  
pp. 200571
Author(s):  
Heba Elmansi ◽  
Aya Roshdy ◽  
Shereen Shalan ◽  
Amina El-Brashy

In this study, determination of terbinafine and itraconazole down to biological concentration level has been carried out. The determination is based on increasing the selectivity of the spectrofluorimetric technique by combining both derivative and synchronous spectrofluorometric approaches, which permits successful estimation of terbinafine at 257 nm and itraconazole at 319 nm in the presence of each other at Δ λ of 60 nm. International Conference on Harmonization validation guidelines were followed to fully validate the method, and linearity was obtained for the two drugs over the range of 0.1–0.7 µg ml −1 for terbinafine and 0.5–4.0 µg ml −1 for itraconazole. Application of the method was successfully carried out in the commercial tablets with good agreement with the comparison spectrofluorometric methods. As the detection limits were down to 0.013 and 0.1 µg ml −1 and quantitation limits were 0.04 and 0.032 µg ml −1 for terbinafine and itraconazole, respectively; the in vitro determination of terbinafine and itraconazole in spiked plasma samples was applicable. The percentage recoveries in biological samples were 97.17 ± 4.54 and 98.75 ± 2.25 for terbinafine and itraconazole, respectively. Water was used as the optimum diluting solvent in the proposed methodology which adds an eco-friendly merit.


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