Electrochemical Characterization of Flupenthixol and Rapid Determination of the Drug in Human Serum and Pharmaceuticals by Voltammetry

2005 ◽  
Vol 38 (4) ◽  
pp. 641-656 ◽  
Author(s):  
Burcu Dogan ◽  
Sibel A. Özkan ◽  
Bengi Uslu
Keyword(s):  
Human Serum ◽  
Rapid Determination ◽  
Electrochemical Characterization

Synthesis, chemical, and electrochemical characterization of the [Ag13{?3-Fe(CO)4}] n? (n = 3, 4, 5) cluster anions: X-Ray structural determination of [N(PPh3)2]3 [Ag12(?12-Ag){?3Fe(CO)4}8]1

1995 ◽  
Vol 6 (1) ◽  
pp. 107-123 ◽  
Author(s):  
Vincenzo G. Albano ◽  
Francesca Calderoni ◽  
Maria Carmela Iapalucci ◽  
Giuliano Longoni ◽  
Magda Monari ◽  
...  
Keyword(s):  
Electrochemical Characterization ◽  
Structural Determination ◽  
Cluster Anions ◽  
X Ray

Characterization of sulfasalazine's interference in the measurement of conjugated bilirubin by the Ektachem slide method.

1989 ◽  
Vol 35 (8) ◽  
pp. 1760-1762 ◽  
Author(s):  
D W Franquemont ◽  
J L Sutphen ◽  
D A Herold ◽  
D E Bruns
Keyword(s):  
Inflammatory Bowel Disease ◽  
Human Serum ◽  
Bowel Disease ◽  
Multilayer Film ◽  
Total Bilirubin ◽  
Inflammatory Bowel ◽  
Film Analyzer ◽  
Conjugated Bilirubin

Abstract We describe the cases of four patients who were taking sulfasalazine for inflammatory bowel disease, whose conjugated bilirubin concentrations in serum exceeded their corresponding total bilirubin concentrations as measured with a multilayer film analyzer, the Ektachem 400. Sulfasalazine added to pooled human serum at therapeutic concentrations increased the apparent conjugated bilirubin, as measured with the Ektachem, in a linear and dose-related fashion. Measured unconjugated bilirubin was simultaneously decreased to values less than -3 mg/L. The same interference occurred on the Ektachem 700, but an algorithm prevented the instrument from reporting the results. The major metabolites of sulfasalazine in blood did not interfere with analysis for those fractions of bilirubin. Sulfasalazine's strong absorbance at 400 nm explains its interference with determination of conjugated bilirubin in this instrument.

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