Enrichment of spreadable fats with polyunsaturated fatty acids omega-3 using fish oil

2001 ◽  
Vol 52 (6) ◽  
pp. 469-476 ◽  
Author(s):  
Wojciech Kolanowski ◽  
Franciszek Swiderski ◽  
Ewa Lis ◽  
Stanislaw Berger
Keyword(s):  
Fatty Acids ◽  
Polyunsaturated Fatty Acids ◽  
Fish Oil ◽  
Omega 3

scholarly journals Successful high‐level accumulation of fish oil omega‐3 long‐chain polyunsaturated fatty acids in a transgenic oilseed crop

2013 ◽  
Vol 77 (2) ◽  
pp. 198-208 ◽  
Author(s):  
Noemi Ruiz‐Lopez ◽  
Richard P. Haslam ◽  
Johnathan A. Napier ◽  
Olga Sayanova
Keyword(s):  
Fatty Acids ◽  
Polyunsaturated Fatty Acids ◽  
Fish Oil ◽  
Oilseed Crop ◽  
Omega 3 ◽  
High Level ◽  
Long Chain

Biomarkers of Fish Oil Omega-3 Polyunsaturated Fatty Acids Intake in Humans

2013 ◽  
Vol 29 (1) ◽  
pp. 63-72 ◽  
Author(s):  
Veronica Silva ◽  
Rocco Barazzoni ◽  
Pierre Singer
Keyword(s):  
Fatty Acids ◽  
Polyunsaturated Fatty Acids ◽  
Fish Oil ◽  
Omega 3

Cardioprotective role of omega-3 polyunsaturated fatty acids

2008 ◽  
Vol 149 (14) ◽  
pp. 627-637 ◽  
Author(s):  
Zsuzsa Varga
Keyword(s):  
Fatty Acids ◽  
Polyunsaturated Fatty Acids ◽  
Fish Oil ◽  
Linseed Oil ◽  
Density Lipoprotein ◽  
Receptor Protein ◽  
Peroxisome Proliferator ◽  
Nuclear Factor ◽  
Omega 3 Fatty Acids ◽  
Omega 3

Cardioprotective action of omega-3 polyunsaturated fatty acids such as eicosapentaenoic and docosahexaenoic acid in fish and α-linolenic acid in plants was demonstrated in primary and secondary clinical trials. Fish oil therapy causes a marked decrease in serum triacylglycerol and very low density lipoprotein levels and increases moderately high density lipoprotein levels without any adverse effects. Omega-3 fatty acids decrease slightly, but significantly blood pressure, enhance endothelial function, they have anti-aggregator, anti-thrombotic and anti-inflammatory effects as well. These beneficial effects are in connection with modification of gene transcription levels of some key molecules such as nuclear factor-κB and sterol element binding receptor protein-1c, which regulate for example expression of adhesion molecules or several receptors involved in triglyceride synthesis (hepatocyte X receptor, hepatocyte nuclear factor 4α, farnesol X receptor, and peroxisome proliferator-activated receptors). On the basis of these observations, the supplementation of the diet with omega-3 fatty acids (fish, fish oil, linseed, and linseed oil or canola oil) is advisable in primary and secondary prevention.

scholarly journals Mitigation of Particulate Matter-Induced Inflammation and Vasoactivity in Human Vascular Endothelial Cells by Omega-3 Polyunsaturated Fatty Acids

2018 ◽  
Vol 15 (10) ◽  
pp. 2293
Author(s):  
Jaya Sriram ◽  
Olorunfemi Adetona ◽  
Tonya Orchard ◽  
Chieh-Ming Wu ◽  
James Odei
Keyword(s):  
Fatty Acids ◽  
Endothelial Cells ◽  
Particulate Matter ◽  
Polyunsaturated Fatty Acids ◽  
Fish Oil ◽  
Umbilical Vein ◽  
Diesel Exhaust Particles ◽  
Omega 3 ◽  
Oil Formulation

Airborne particulate matter (PM) exposure remains the leading environmental risk factor for disease globally. Interventions to mitigate the adverse effects of PM are required, since there is no discernible threshold for its effects, and exposure reduction approaches are limited. The mitigation of PM (specifically diesel exhaust particles (DEP))-induced release of pro-inflammatory cytokines interleukin-6 (IL-6) and interleukin-8 (IL-8) and vasoconstrictor endothelin-1 (ET-1) after 24 and 48 h of exposure by pre-treatment with individual pure, combined pure, and an oil formulation of two fish oil omega-3 polyunsaturated fatty acids (ω-3 PUFAs), docosahexaenoic acid (DHA), and eicosapentaenoic acid (EPA) were all tested at an equivalent concentration of 100 µM in vitro in human umbilical vein endothelial cells. The PUFAs and fish oil formulation completely mitigated or diminished the DEP-induced release of IL-6, IL-8, and ET-1 by 14–78%. DHA was more effective in reducing the levels of the DEP-induced release of the cytokines, especially IL-6 after 48 h of DEP exposure in comparison to EPA (p < 0.05), whereas EPA seemed to be more potent in reducing ET-1 levels. The potential of fish ω-3 PUFAs to mitigate PM-induced inflammation and vasoactivity was demonstrated by this study.

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