SUCCESSFUL TREATMENT OF AN ENDODERMAL SINUS TUMOR OF THE VAGINA BY CHEMOTHERAPY ALONE: A Rare Case of an Infant Diagnosed by Pathological Examination of Discharged Tumor Fragment

2006 ◽  
Vol 23 (7) ◽  
pp. 563-569 ◽  
Author(s):  
Yuichi Shinkoda ◽  
Satoru Tanaka ◽  
Osamu Ijichi ◽  
Hideki Yoshikawa ◽  
Yukiko Nonaka ◽  
...  
1994 ◽  
Vol 11 (5) ◽  
pp. 553-556
Author(s):  
Teresa Depowska ◽  
Ewa Zalçska-Czepko ◽  
Jerzy Armata

Cancer ◽  
1992 ◽  
Vol 70 (9) ◽  
pp. 2260-2262 ◽  
Author(s):  
J. S. Whelan ◽  
W. Stebbings ◽  
R. A. Owen ◽  
R. Calne ◽  
P. I. Clark

1988 ◽  
Vol 31 (2) ◽  
pp. 357-364 ◽  
Author(s):  
M. Ohta ◽  
K. Sakakibara ◽  
K. Mizuno ◽  
T. Kano ◽  
K. Matsuzawa ◽  
...  

2013 ◽  
Vol 2 (1) ◽  
Author(s):  
Poppy M. Lintong

Abstract: Germ cell tumors of the ovary are primary ovarian tumors which derived from primitive germinal cells. These tumors are derived from primitive germinal cells. The total incidence of these tumors is around 30% of all tumors, and are mostly found in children and young adults. The etiology and pathogenesis  of these tumors are not clearly defined, but some studies have shown that etiology is related to genetic origin. WHO classification divides these germ cell tumors of the ovarian into two groups: dysgerminoma and the other ovarian germ cell tumors, which consist of pure types and mixed types. The pure type consists of endodermal sinus tumor, embryonal carcinoma, polyembryoma, choriocarcinoma, anda teratoma. Dysgerminoma is the most frequent malignant type. This tumor has characteristic microscopic features and different histo-logical variants, which sometimes leads to difficulty in making a diagnosis. Immuno-histochemical tests are needed for making several differential diagnoses and finding the most appropriate diagnosis. Pathological examination of tissues and ascites fluid are also important in determi-nation of the clinical stages, which play some important roles in managing the therapy and prognosis. Keywords: germ cell tumors, ovarium, pathogenesis, classification, dysgerminoma.     Abstrak: Germ cell tumors ovarium merupakan tumor primer ovarium yang berasal dari sel-sel germinal primitif. Insidennya kira-kira 30% dari seluruh tumor ovarium, dan teruta-ma menyerang anak-anak dan dewasa muda. Etiologi dan patogenesis dari germ cell tumors ovarium belum diketahui dengan jelas, namun beberapa studi telah menunjukkan  bahwa hal ini ada hubungannya dengan etiologi genetik. Menurut klasifikasi WHO germ cell tumors ovarium digolongkan atas dua bagian besar yaitu dysgerminoma, dan germ cell tumors ovarium lainnya, yang terdiri dari bentuk murni dan campuran. Bentuk murni terdiri dari endodermal sinus tumor, embryonal carcinoma, polyembryoma, chorio-carcinoma, dan teratoma. Dysgerminoma merupakan germ cell tumors ovarium ganas tersering. Tumor ini mempunyai ciri-ciri mikroskopik yang karakteristik dan varian histologik berbeda-beda, yang kadang-kadang dapat menimbulkan problem diagnostik karena sulit dibedakan dengan jenis tumor yang lain. Dalam melakukan diagnosis banding  dan menegaskan diagnosis secara pasti perlu dilakukan pemeriksaan imunohistokimia. Pemeriksaan patologi jaringan dan sitologi cairan asites  penting dalam penentuan stadium klinik, dan hal ini berpengaruh terhadap pilihan pengobatan dan prognosis penderita. Pada tulisan ini selain  dibahas tentang germ cell tumors ovarium secara umum, juga dibahas salah satu germ cell tumors ovarium yang tersering yaitu dysgerminoma. Kata kunci: germ cell tumors, ovarium, patogenesis, klasifikasi, dysgerminoma.


1989 ◽  
Vol 28 (4) ◽  
pp. 393-393
Author(s):  
M Ohta ◽  
K Sakakibara ◽  
K Mizuno ◽  
T Kano ◽  
K Matsuzawa ◽  
...  

1991 ◽  
Vol 74 (5) ◽  
pp. 832-836 ◽  
Author(s):  
Carine S. Kirkove ◽  
Andrew P. Brown ◽  
Lindsay Symon

✓ A patient with a pineal endodermal sinus tumor is presented who was successfully treated by a combination of surgery, adjuvant chemotherapy, and craniospinal irradiation. Two years after diagnosis, he is free of any disease. A review of the literature shows that such an outcome is very unusual. A multidisciplinary treatment is recommended for this rare tumor, using chemotherapy as adjuvant treatment.


Cureus ◽  
2020 ◽  
Author(s):  
Muhammad Noor ◽  
Berenice L Leal ◽  
Dhruv Patel

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Guiqin Chen ◽  
Lei Nie ◽  
Tijiang Zhang

Abstract Background The accessory spleen has no anatomical or vascular relationship with the normal spleen, The tissue structure and physiological function of the accessory spleen are the same as those of the normal spleen, which usually locate in the splenic hilum and the tail of the pancreas. The aims of this manuscript are to present a rare case of the gastric accessory spleen and a review of the literature. Case presentation A 19-year-old male patient was sent to the emergency department with stomach bleeding after drinking alcohol. The computed tomographic scan showed a 1.2 cm × 1.7 cm mass at the lesser curvature of the gastric fundus. Gastrointestinal endoscopy displayed a submucosal elevated lesion on the gastric fundus, and gastrectomy was performed. Postoperative pathological examination proved an accessory spleen in the stomach. The postoperative course was uneventful, and the patient was discharged on the 6th day after the surgery. Conclusions The accessory spleen at the fundus of stomach is extremely rare, especially in this case, which is accompanied by acute gastric bleeding, and it is difficult to diagnosis before operation. Many literatures reported that it was misdiagnosis as tumor, so it is necessary to diagnose accessory spleen correctly.


2013 ◽  
Vol 76 (2) ◽  
pp. 112-114 ◽  
Author(s):  
Yi-Wen Chang ◽  
Kuan-Chong Chao ◽  
Pi-Lin Sung ◽  
Wai Hou Li ◽  
Peng-Hui Wang

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