A 5-Year Comparison of Doxazosin and Atenolol in Patients With Mild-to-Moderate Hypertension: Effects on Blood Pressure, Serum Lipids, and Coronary Heart Disease Risk

1998 ◽  
Vol 7 (1) ◽  
pp. 39-45 ◽  
Author(s):  
LUDVIG N. W. DAAE, LARS WESTLIE
Keyword(s):  
Blood Pressure ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Coronary Heart Disease Risk ◽  
Serum Lipids ◽  
Moderate Hypertension ◽  
Disease Risk ◽  
Heart Disease Risk

scholarly journals Amlodipine Reduces Predicted Risk of Coronary Heart Disease in High-Risk Patients with Hypertension in Spain (The CORONARIA Study)

2008 ◽  
Vol 36 (6) ◽  
pp. 1399-1417
Author(s):  
J Zamorano ◽  
L Rodriguez Padial ◽  
J Cosín ◽  
A Hernandiz ◽  
JL Gutierrez-Chico ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
High Risk ◽  
Coronary Heart Disease Risk ◽  
Disease Risk ◽  
Antihypertensive Agents ◽  
Blood Pressure Target ◽  
Open Label ◽  
Heart Disease Risk

We evaluated the efficacy and safety of amlodipine besylate alone or in combination with other antihypertensive agents in high-risk hypertensive patients in Spanish primary care. In this 1-year, open-label, prospective cohort study, 7468 patients were treated with amlodipine 5–10 mg as a monotherapy or as an add-on therapy to attain blood pressure control (target of < 140/90 mmHg or, in patients with conditions such as diabetes or chronic kidney disease, < 130/85 mmHg). At 12 months, the primary outcome (change from baseline in predicted 10-year coronary heart disease risk) was −8.6%, down from 24.7% at baseline (relative risk reduction, 31.6%). Change in blood pressure from baseline (162.5/95.3 mmHg) was −26.7/-14.6 mmHg, and 38.6% of patients achieved their blood pressure target. In summary, significant reductions in predicted coronary heart disease risk and blood pressure were observed with amlodipine both as a monotherapy and as an add-on therapy. Amlodipine was well tolerated and compliance with treatment was good.

scholarly journals Aggressive Blood Pressure Control Increases Coronary Heart Disease Risk Among Diabetic Patients

Diabetes Care ◽  
2013 ◽  
Vol 36 (10) ◽  
pp. 3287-3296 ◽  
Author(s):  
W. Zhao ◽  
P. T. Katzmarzyk ◽  
R. Horswell ◽  
Y. Wang ◽  
W. Li ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Blood Pressure Control ◽  
Coronary Heart Disease Risk ◽  
Disease Risk ◽  
Pressure Control ◽  
Diabetic Patients ◽  
Heart Disease Risk

A Randomised Controlled Trial of Counseling in a Workplace Setting for Coronary Heart Disease Risk Factor Modification: Effects on Blood Pressure

1990 ◽  
Vol 4 (1) ◽  
pp. 25-33 ◽  
Author(s):  
Michael S Frommer ◽  
John A Mandryk ◽  
Beryl V Edye ◽  
Sandra Healey ◽  
Geoffrey Berry ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Coronary Heart Disease ◽  
Risk Factor ◽  
Heart Disease ◽  
Coronary Heart Disease Risk ◽  
Disease Risk ◽  
Controlled Trial ◽  
Counseling Program ◽  
Randomised Controlled ◽  
Heart Disease Risk

This paper reviews a prospective study of occupational factors in coronary heart disease risk incorporated in a randomised controlled trial of a worksite based occupational health nurse counseling program for reducing coronary heart disease risk factors. The aim of the trial was to evaluate the longterm effectiveness of the counseling program in persons with mildly elevated risk factor levels. Of the 2, 489 Australian government employees with mildly elevated risk factor levels who entered the intervention trial, 1, 937 (78%) attended a followup examination three years later. This paper reports on changes in systolic and diastolic blood pressure. Multiple linear regression models were used with three-year blood pressure reduction as the dependent variable, intervention status as the main determinant, and sex, age, initial risk level and initial blood pressure as covariates. Although systolic and diastolic blood pressure fell in both the intervention and control groups, intervention was significantly associated with systolic blood pressure change only.

scholarly journals Does the Relation of Blood Pressure to Coronary Heart Disease Risk Change With Aging?

Circulation ◽  
2001 ◽  
Vol 103 (9) ◽  
pp. 1245-1249 ◽  
Author(s):  
Stanley S. Franklin ◽  
Martin G. Larson ◽  
Shehzad A. Khan ◽  
Nathan D. Wong ◽  
Eric P. Leip ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Coronary Heart Disease Risk ◽  
Disease Risk ◽  
Heart Disease Risk
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