The regulatory role of nerve growth factor and its receptor system in fibroblast‐like synovial cells

2009 ◽  
Vol 38 (3) ◽  
pp. 207-215 ◽  
Author(s):  
S. P. Raychaudhuri ◽  
S. K. Raychaudhuri
Keyword(s):  
Nerve Growth Factor ◽  
Growth Factor ◽  
Regulatory Role ◽  
Synovial Cells ◽  
Receptor System ◽  
Nerve Growth

scholarly journals Role of Nerve Growth Factor in Development and Persistence of Experimental Pulmonary Hypertension

2015 ◽  
Vol 192 (3) ◽  
pp. 342-355 ◽  
Author(s):  
Véronique Freund-Michel ◽  
Marcelina Cardoso Dos Santos ◽  
Christophe Guignabert ◽  
David Montani ◽  
Carole Phan ◽  
...  
Keyword(s):  
Pulmonary Hypertension ◽  
Nerve Growth Factor ◽  
Growth Factor ◽  
Nerve Growth

trkC, a receptor for neurotrophin-3, is widely expressed in the developing nervous system and in non-neuronal tissues

Development ◽  
1993 ◽  
Vol 118 (2) ◽  
pp. 463-475 ◽  
Author(s):  
L. Tessarollo ◽  
P. Tsoulfas ◽  
D. Martin-Zanca ◽  
D.J. Gilbert ◽  
N.A. Jenkins ◽  
...  
Keyword(s):  
Nerve Growth Factor ◽  
Growth Factor ◽  
Tyrosine Kinases ◽  
Expression Patterns ◽  
Developmental Expression ◽  
Receptor System ◽  
Nerve Growth ◽  
Trk Receptor ◽  
Neurotrophin 3 ◽  
Neuronal Tissues

The Trk family of tyrosine kinases encodes receptors for nerve growth factor-related neurotrophins. Here we present a developmental expression study of trkC, which encodes a receptor for neurotrophin-3 (NT-3). Like the related genes, trk and trkB, trkC is expressed primarily in neural lineages although the pattern is complex and includes non-neuronal cells. Direct comparison with trk and trkB developmental expression patterns permits the following observations. (1) trkC is expressed in novel neural tissues where other Trk genes are silent. (2) Some tissues appear to coexpress trkB and trkC receptors in the embryo and in the adult. (3) trkC expression can be detected in the gastrulating embryo. These data provide insights into the role of Trk-family receptors and nerve growth factor-related neurotrophins during development and suggest that, in addition to regulating neuronal survival and differentiation, the neurotrophin/Trk receptor system may have broader physiological effects. Finally, interspecific mouse backcrosses have been used to map the location of each of the Trk genes on mouse chromosomes. Alignment with available chromosomal maps identify possible linkage between the Trk genes and known neurological mutations.

scholarly journals Role of Connexin 43 increased expression in pulmonary arterial hyperreactivity induced by the nerve growth factor NGF

2019 ◽  
Vol 11 (2) ◽  
pp. 203
Author(s):  
G. Cardouat ◽  
M. Douard ◽  
P. Robillard ◽  
M. Dubois ◽  
R. Marthan ◽  
...  
Keyword(s):  
Nerve Growth Factor ◽  
Growth Factor ◽  
Connexin 43 ◽  
Nerve Growth ◽  
Pulmonary Arterial
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