Lumbar subcutaneous shunt: a novel technique for therapeutic decision making in normal pressure hydrocephalus (NPH) and benign intracranial hypertension (BIH)

2008 ◽  
Vol 22 (5) ◽  
pp. 678-681 ◽  
Author(s):  
S. Ushewokunze ◽  
H. N. Haja Mydin ◽  
R. Prasad ◽  
A. D. Mendelow
Keyword(s):  
Decision Making ◽  
Intracranial Hypertension ◽  
Normal Pressure Hydrocephalus ◽  
Normal Pressure ◽  
Benign Intracranial Hypertension ◽  
Therapeutic Decision ◽  
Novel Technique ◽  
Therapeutic Decision Making

Vasopressin in the cerebrospinal fluid of patients with normal pressure hydrocephalus and benign intracranial hypertension

1982 ◽  
Vol 100 (2) ◽  
pp. 211-215 ◽  
Author(s):  
Mogens Hammer ◽  
Per Soelberg Sørensen ◽  
Flemming Gjerris ◽  
Kim Larsen
Keyword(s):  
Cerebrospinal Fluid ◽  
Intracranial Hypertension ◽  
Normal Pressure Hydrocephalus ◽  
Plasma Osmolality ◽  
Normal Pressure ◽  
Lumbar Pain ◽  
Control Group ◽  
Benign Intracranial Hypertension ◽  
Severe Dementia ◽  
Pain Syndromes

Abstract. We have studied plasma and cerebrospinal fluid vasopressin (CSF-AVP) and osmolality in 28 patients with cervical or lumbar pain syndromes (control patients), 11 patients with normal pressure hydrocephalus (NPH) and in 5 patients with benign intracranial hypertension (BIH). Vasopressin concentration in lumbar CSF to a high extent reflected the actual ventricular CSF-AVP concentration. In all groups CSF-AVP was lower than plasma AVP. Mean CSF-AVP in the control group was 1.3 pg/ml ± 0.1 (sem). In the NPH patients, who all suffered from severe dementia, CSF-AVP level was not different from that found in the control group (1.4 pg/ml ± 0.2). In contrast to the findings in the two other groups CSF osmolality in BIH patients was higher than plasma osmolality (P < 0.02). CSF-AVP in the BIH patients, characterized by an elevated intracranial pressure (ICP), was higher than in the control group (2.7 pg/ml ± 0.4, P < 0.001).

The Prescription as Final Common Pathway

1995 ◽  
Vol 11 (3) ◽  
pp. 384-390 ◽  
Author(s):  
Jerry Avorn
Keyword(s):  
Decision Making ◽  
Cost Effectiveness ◽  
Health Economics ◽  
Medical Care ◽  
Clinical Medicine ◽  
Decision Science ◽  
Therapeutic Decision ◽  
Common Pathway ◽  
Final Common Pathway ◽  
Therapeutic Decision Making

AbstractThere is an informational void about Pharmaceuticals in the training of most doctors, despite the importance of the prescription in medical care. The writing of the prescription is the final common pathway in therapeutic decision making, which involves such diverse forces and disciplines as anthropology, decision science, health economics, ethics, and politics, as well as pharmacology and clinical medicine. Programs to improve the precision and cost-effectiveness of doctors' prescribing must consider all of these factors if pharmacotherapeutics are to be used optimally.

Therapeutic decision making in BMT/SCT for hemoglobinopathies

2013 ◽  
pp. 179-191
Author(s):  
Shalini Shenoy ◽  
Reinhold Munker ◽  
Kerry Atkinson
Keyword(s):  
Decision Making ◽  
Therapeutic Decision ◽  
Therapeutic Decision Making
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