scholarly journals Anaemia, iron deficiency and vitamin A status among school-aged children in rural Kazakhstan

2005 ◽  
Vol 8 (6) ◽  
pp. 564-571 ◽  
Author(s):  
Masahiro Hashizume ◽  
Momoko Chiba ◽  
Atsuko Shinohara ◽  
Shigehiro Iwabuchi ◽  
Satoshi Sasaki ◽  
...  
Keyword(s):  
Iron Deficiency ◽  
Vitamin A ◽  
Serum Iron ◽  
Binding Capacity ◽  
Transferrin Saturation ◽  
Serum Retinol ◽  
Cross Sectional ◽  
School Aged Children ◽  
Vitamin A Status ◽  
Cross Sectional Design

AbstractObjectivesTo investigate the prevalence of anaemia and iron deficiency and vitamin A status among school-aged children in rural Kazakhstan and identify factors associated with anaemia in this population.DesignA cross-sectional design.SettingSchool-aged children in rural Kazakhstan.SubjectsSocio-economic and anthropometric information was collected from 159 school-aged children living in the Kzyl-Orda region of Kazakhstan. Blood samples were collected and the concentrations of haemoglobin (Hb), serum iron, serum ferritin (SF), erythrocyte protoporphyrin (EP), serum retinol and β-carotene, total iron binding capacity (TIBC), transferrin saturation (TS) and other haematological indices were measured.ResultsAmong the 159 children, the prevalence of anaemia and iron deficiency defined by the multiple criteria model (SF, TS and EP) was 27% and 13%, respectively. Nine per cent had iron-deficiency anaemia and 21% had serum retinol value <1.05 μmol l−1. Mean SF and serum iron concentrations and TS were significantly lower in anaemic children than in their non-anaemic peers, while TIBC and EP were significantly higher in children with anaemia. Hb was significantly correlated with serum iron and retinol concentrations. Serum retinol and SF concentrations and mean corpuscular volume were significantly correlated with Hb by multiple regression analysis.ConclusionsAnaemia among school-aged children in rural Kazakhstan appears to be related to iron indices and vitamin A status.

scholarly journals Hubungan Kadar Komponen Besi Darah Pendonor terhadap Kualitas Packed Red Cells (PRC) di UDD PMI Provinsi Sumatera Selatan

2021 ◽  
Vol 7 (1) ◽  
pp. 66-71
Author(s):  
Rahmi Widiyawati ◽  
Zen Hafy ◽  
Phey Liana
Keyword(s):  
Iron Deficiency ◽  
Serum Iron ◽  
Transferrin Saturation ◽  
Red Cells ◽  
Component Level ◽  
Cross Sectional ◽  
Second Stage ◽  
Cross Sectional Design ◽  
The Relationship

Iron is the essential component of our body especially used to make Hemoglobin. If the intake of iron enters from our food less than issued, it makes our reserve iron will be used, and it can cause iron deficiency. There are three pathogenesis stages of iron deficiency, first marked by reduced iron reserve or the absence of iron reserved, ferritin levels decreased, while other parameters to determinate the presence of iron deficiency( Serum Iron, TIBC, Hb, Transferrin Saturation) are still normal. The purpose of this study was to analyze the relationship level of donor iron components and quality of Packed Red Cells (PRC) in UDD PMI Provinsi Sumatera Selatan. This research is an analytic observational study with a cross-sectional design. The result of the research was conducted in April 2021, using 86 blood samples from donors. It showed there were 15 samples with iron deficiency. Consisted of 9 samples with iron deficiency in the first stage and 6 samples in the second stage. It is known that there are 6 samples with poor PRC quality; all of them are iron deficiency in the second stage. In conclusion, there is a significant relationship iron component level of the donor and the quality of PRC p<0,05.

Serum iron and total iron-binding capacity compared with serum ferritin in assessment of iron deficiency.

1981 ◽  
Vol 27 (2) ◽  
pp. 276-279 ◽  
Author(s):  
F Peter ◽  
S Wang
Keyword(s):  
Iron Deficiency ◽  
Serum Ferritin ◽  
Serum Iron ◽  
Binding Capacity ◽  
Transferrin Saturation ◽  
Total Iron ◽  
Iron Binding ◽  
Total Iron Binding Capacity ◽  
Iron Deficient ◽  
Iron Binding Capacity

Abstract Ferritin values for 250 selected sera were compared with values for iron, total iron-binding capacity (TIBC), and transferrin saturation, to assess the potential of the ferritin assay for the detection of latent iron deficiency. The specimens were grouped (50 in each group) according to their values for iron and TIBC. In Group 1 (low iron, high TIBC) the saturation and ferritin values both indicated iron deficiency in all but one. In the 100 specimens of Groups 2 (normal iron, high TIBC) and 4 (normal iron, high normal TIBC), the saturation values revealed 16 iron-deficient cases, the ferritin test 55. For Groups 3 (low iron, normal TIBC) and 5 (low iron, low TIBC), the ferritin test revealed fewer cases of iron deficiency than did the saturation values (37 cases vs 51 cases, in the 100 specimens). Evidently the ferritin test detects iron deficiency in many cases for whom the serum iron and TIBC tests are not positively indicative. The correlation of serum ferritin with iron, TIBC, and transferrin saturation in the five groups was good only in the case of specimens for which the TIBC was normal; if it was abnormal the correlation was very poor.

scholarly journals Vitamin A and Nutritional Anaemia

1996 ◽  
Vol 17 (1) ◽  
pp. 1-3 ◽  
Author(s):  
Djoko Suharno ◽  
Muhilal
Keyword(s):  
Placebo Group ◽  
Iron Deficiency ◽  
Vitamin A ◽  
Pregnant Women ◽  
Iron Supplementation ◽  
Ferrous Sulphate ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Vitamin A Status

A cross-sectional study of the prevalence of iron and vitamin A deficiencies in 318 pregnant women revealed that 50.7% had iron deficiency and 21.3% had marginally deficient or deficient vitamin A status. Based on results, the influence of vitamin A and iron supplementation was studied in 305 anaemic pregnant women in west Java, in a randomized, doubleblind, placebo-controlled field trial. The women with a haemoglobin between 80 and 109 g/L were randomly allocated to four groups: vitamin A (2.4 mg retinol) and placebo iron tablets; iron (60 mg elemental iron as ferrous sulphate) and placebo vitamin A; vitamin A and iron; and both placebos, all daily for eight weeks. Maximum haemoglobin was achieved with both vitamin A and iron supplementation (12. 78 g/L, 95% Cl 10.86 to 14.70), with one-third of the response attributable to vitamin A (3.68 g/L, 2.03 to 5.33) and two-thirds to iron (771 g/L, 5.97 to 9.45). After supplementation, the proportion of women who became non-anaemic was 35 % in the vitamin Asupplemented group, 68% in the ironsupplemented group, 97% in the group supplemented with both, and 16% in the placebo group. We conclude that improvement in vitamin A status may contribute to the control of anaemia in pregnant women.

Subclinical Iron Deficiency in Non-Anemic Individuals: A Retrospective Analysis of Korean Health Examinees

2019 ◽  
Vol 143 (1) ◽  
pp. 26-32
Author(s):  
Eun-Hee Nah ◽  
Han-Ik Cho ◽  
Seon Cho ◽  
Suyoung Kim
Keyword(s):  
Iron Deficiency ◽  
Blood Cell ◽  
Serum Iron ◽  
Binding Capacity ◽  
Transferrin Saturation ◽  
Reproductive Age ◽  
Iron Level ◽  
Distribution Width ◽  
Elderly Males ◽  
Males And Females

Objectives: Non-anemic individuals may have undetected subclinical iron deficiency (SID). The aims of this study were to determine the prevalence of SID and identify the associated factors for SID. In addition, the screening performance of red blood cell (RBC) indices for SID in health check-ups was assessed. Methods: This study was conducted with 16,485 non-anemic health examinees (3,567 males and 12,918 females) who underwent tests for iron variables (serum iron, total iron-binding capacity, ferritin, and iron saturation) at 16 health-promotion centers in 13 cities in Korea between January 2017 and June 2018. SID was defined as a decreased ferritin level (<24 µg/L in males and <15 µg/L in females) and either a decreased serum iron level (<44 µg/dL in males and <29 µg/dL in females) or a transferrin saturation of <20%. Results: The prevalence rates of SID were 0.6 and 3.3% in males and females, respectively. In terms of age and sex, SID was most prevalent in males aged ≥70 years (7.8%) and females aged 15–49 years (7.6%). There were significant differences in the hemoglobin (Hb) level, white blood cell count, platelet count, mean corpuscular volume, mean corpuscular Hb (MCH), and RBC distribution width (RDW) between the SID and non-SID groups (p < 0.001). The factors associated with SID in males were older age (odds ratio, OR, 1.069, 95% confidence interval, CI, 1.03–1.109, p = 0.004), lower Hb (OR 0.58, 95% CI 0.345–0.976, p = 0.04), lower MCH (OR 0.433, 95% CI 0.298–0.629, p < 0.001), and higher RDW (OR 1.374, 95% CI 1.001–1.887, p = 0.049), while in females they were lower body mass index (BMI; OR 0.929, 95% CI 0.895–0.963, p < 0.001) and younger age (OR 0.954, 95% CI 0.945–0.963, p < 0.001), as well as lower Hb, lower MCH, and higher RDW. The AUC for the MCH (0.877, 95% CI 0.793–0.960 in males; 0.872, 95% CI 0.853–0.890 in females) indicates that the MCH at cut-offs of 29.2 and 29.3 pg are the best discriminators of SID in males and females, respectively (p < 0.001). Conclusions: Reproductive-age females with a lower BMI and elderly males are high-risk groups for SID. MCH is a reliable RBC index for the screening of SID. For the population with defined risk factors, including females with lower BMI and elderly males, screening for SID is needed to prevent the development of anemia.

scholarly journals Prevalence and associated risk factors of iron deficiency without anemia among school adolescents in Mbouda, Western Cameroon

2022 ◽  
Author(s):  
Odile Tadzong Mamokem ◽  
Wiliane Jean Takougoum Marbou ◽  
Marie Modestine Kana Sop ◽  
Bruno Phélix Telefo
Keyword(s):  
Risk Factors ◽  
Iron Deficiency ◽  
Serum Iron ◽  
Binding Capacity ◽  
Transferrin Saturation ◽  
School Site ◽  
Mean Values ◽  
Significant Difference ◽  
Associated Risk Factors ◽  
Iron Binding Capacity

Background: Adolescents are a particularly vulnerable age group to iron deficiency without anemia (IDWA). This study aimed at determining the prevalence and associated risks factors of IDWA among apparently healthy school teenagers in Mbouda, West-Cameroon.Methods: The 778 blood samples were randomly collected from adolescents aged 10-19 years of four schools in Mbouda. Appropriate indicators including haemoglobin and haematocrit, serum iron, ferritin, transferrin, and total iron binding capacity, transferrin saturation were determined using standard methods.Results: The overall prevalence of IDWA was 40.4%. High significant difference in the mean values of serum iron (p≤0.001), serum ferritin (p≤0.001), TIBC (p=0.007), CST (p≤0.001) were observed in participants with IDWA compared to those without IDWA. The sociodemographic risk factors of IDWA in school adolescents were school site (p=0.022; 0.14 (0.90-1.43) and period of menstruation (p=0.015; 1.48 (1.083-2.03). Consumption of roots-tubers [OR: 0.92 (0.48-1.77)] legumes [OR: 2.65 (1.91-3.67)], cereals [OR: 0.90 (0.67-1.22)], increased the risk of IDWA while consumption of vegetables [OR: 0.29 (0.22-0.39)], eggs [OR: 0.66 (0.49-0.90)], and fish-shrimp [OR: 0.172 (0.10-0.295)] decreased the risk of IDWA. Meal consumption frequency had a statistically significant association with IDWA (p≤0.001).Conclusions: This study identified that IDWA was a major public health in adolescents. This study will help in planning and implementation of the policy for prevention of IDWA in adolescents.

scholarly journals Reducing iron deficiency anaemia due to heavy menstural blood loss in Nigerian rural adolescents. Reprinted from Public Health Nutrition Volume 1 (4), 249–257, 1998

2005 ◽  
Vol 8 (5) ◽  
pp. 451-460
Author(s):  
Fiona Barr ◽  
Loretta Brabin ◽  
Shola Agbaje ◽  
Feikumo Buseri ◽  
John Ikimalo ◽  
...  
Keyword(s):  
Iron Deficiency ◽  
Serum Iron ◽  
Iron Deficiency Anaemia ◽  
Iron Status ◽  
Transferrin Saturation ◽  
Cultural Barriers ◽  
Menstrual Disorders ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Deficiency Anaemia

AbstractObjectiveMenstrual disorders are common in young women, and heavy menstrual blood losses (MBL) are an important cause of anaemia. Menstrual morbidity normally goes untreated in developing countries where cultural barriers also serve to make the problems. We investigated the prevelance of menstrual morbidity, and measured MBL and its relationship to iron deficiency in a rural adolescent population. The rationale was to assess whether or not reducing heavy MBL could be part of a strategy to reduce iron deficiency anaemia.SettingRural village in south-east Nigeria.DesignCross-sectional survey.SubjectsThe studdy included all non-pregnant, unmarried nulliparous girls (< 20 years) who had menstruated, and who lived in K'Dere village.MethodsA field worker allocated to each girl completed a questionnaire, and supervised recovery and collection of soiled pads and ensured blood sampling. MBL was measured using the standard alkaline haematin method. Haemoglobin (HB), serum iron, transferin saturation and protoporphyrin levels (ZPP) were also measured.Results307 girls completed MBL measurements; 11.9% refused to participate. 12.1% had menorrhagia (> 80 ml);. median MBL was 33.1 ml. Menorrhagia was more frequent in girls who had menstruated for > 2 years (p = 0.048), and had longer duration of meneses (p < 0.001). Iron status as measured by haematocrit, serum iron, transferrin saturation and ZPP values was inversely related to MBL. Neither height nor body mass index for age was associated with current iron status.ConclusionsThe level of menorrhagia detected (12%) may be an ‘expected’ level for a condition which often has no underlying pathology. Heavy MBL is one of the most important factors contributing to iron deficiency anaemia. Measures are needed to alleviate menstrual disorders and improve iron status. Oral contraceptives can be part of a strategy to reduce anaemia, particularly for adolescents at high risk of unwanted pregnancies.

scholarly journals Profil zat besi (Fe) pada ibu hamil dengan anemia di Puskesmas Bahu Manado

e-CliniC ◽  
2016 ◽  
Vol 4 (1) ◽  
Author(s):  
Florencia T. Paendong ◽  
Eddy Suparman ◽  
Hermie M. M. Tendean
Keyword(s):  
Health Care ◽  
Iron Deficiency ◽  
Pregnant Women ◽  
Serum Iron ◽  
Sampling Method ◽  
Iron Level ◽  
Cross Sectional ◽  
Developed Country ◽  
Primary Health ◽  
Cross Sectional Design

Abstract: Anemia due to iron deficiency is one of the major causes of anemia among Indonesian pregnant women. In developed country, the deaths of mothers and infants are relate to anemia caused by iron deficiency. This study aimed to obtain the profile of maternal anemia at the primary health care Bahu Manado. This was a descriptive prospective study with a cross sectional design. Samples were sobtained by using total sampling method consisted of 40 pregnant women. Serum iron (SI) was examined among anemic pregnant women. The results showed that of the 40 pregnant women, 13 (32.5%) had anemia. Of the 13 anemic pregnant women, 8 (61.5%) had decreased SI. The analysis found that there was a relation between age, age of pregnancy, parity, education, and job with anemia and decreased SI. It is recommended to consume enough iron during pregnancy and have a regular check up, and treatment in case that the iron level is not optimal.Keywords: anemia, pregnant woman, iron deficiency Abstrak: Anemia defisiensi besi merupakan penyebab utama terjadinya anemia pada ibu hamil di Indonesia dengan prevalensi yang cukup tinggi sehingga masih menjadi masalah kesehatan masyarakat. Di negara berkembang kematian ibu dan janin berkaitan dengan anemia pada kehamilan dan kebanyakan anemia pada kehamilan disebabkan oleh defisiensi besi. Penelitian ini bertujuan untuk mengetahui profil zat besi (Fe) pada ibu hamil dengan anemia di Puskesmas Bahu Manado. Jenis penelitian deskriptif prospektif dengan desain potong lintang. Pemilihan sampel menggunakan metode total sampling yaitu dengan menggunakan seluruh populasi berjumlah 40 orang. Serum iron (SI) diperiksa pada ibu hamil dengan anemia. Hasil penelitian menunjukkan dari 40 ibu hamil yang berkunjung ke Puskesmas Bahu Manado, didapatkan 13 (32,5%) ibu hamil mengalami anemia. Dari 13 ibu hamil yang anemia, didapatkan 8 (61,5%) ibu hamil mengalami penurunan kadar SI . Hasil analisis mendapatkan hubungan antara usia, usia kehamilan, paritas, pendidikan dan pekerjaan dengan anemia dan penurunan kadar SI pada ibu hamil. Disarankan kepada ibu hamil untuk memenuhi asupan zat besi saat hamil dan melakukan kontrol pemeriksaan serta mendapatkan pengobatan bila kadar zat besi (Fe) tidak berada pada nilai optimal. Kata kunci: anemia, ibu hamil, defisiensi besi

scholarly journals Vitamin A status among children in China

2006 ◽  
Vol 9 (8) ◽  
pp. 955-960 ◽  
Author(s):  
Jiang Jingxiong ◽  
André Michael Toschke ◽  
Rüdiger von Kries ◽  
Berthold Koletzko ◽  
Lin Liangming
Keyword(s):  
Vitamin A ◽  
Vitamin A Deficiency ◽  
Risk Groups ◽  
Serum Retinol ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Entire Study ◽  
The Poor ◽  
Vitamin A Status ◽  
Western Area

AbstractObjectiveThe objective of this study was to assess the prevalence of vitamin A deficiency (VAD) in children under 6 years old in China and to identify risk groups for VAD.DesignA cross-sectional survey was conducted in 14 provinces from coastal, inland and western geographic areas in China.SettingOne city (urban) and two counties (rural) were randomly selected from each province as survey areas.SubjectsAbout 200 children aged 0–6 years were randomly selected in each survey area. A blood sample was collected from each child. Data on sociodemographics and nutrition were obtained by interview of the mother or principal caregiver. Fluorescence microanalysis was used to analyse serum retinol concentration.ResultsVAD (serum retinol < 0.7 μmol l− 1) was observed in 957 out of 7826 children aged 0–6 years (12.2% of the entire study population), whereas severe VAD (serum retinol < 0.35 μmol l− 1) was found in 39 children (0.5%). The highest prevalences of VAD at >1 year of age were observed among children of mothers with minority ethnicity (22.7%) or poor education (19.8%) and in the poor western area (17.4%).ConclusionsVAD is a nutritional problem in children in China. Children living in the poor western area, having a mother with minority ethnicity or a mother with poor education have a high risk of VAD.

Anaemia, iron status and vitamin A deficiency among adolescent refugees in Kenya and Nepal

2006 ◽  
Vol 9 (1) ◽  
pp. 26-34 ◽  
Author(s):  
Bradley A Woodruff ◽  
Heidi Michels Blanck ◽  
Laurence Slutsker ◽  
Susan T Cookson ◽  
Mary Kay Larson ◽  
...  
Keyword(s):  
Iron Deficiency ◽  
Vitamin A ◽  
Vitamin A Deficiency ◽  
Iron Status ◽  
Risk Groups ◽  
Refugee Camps ◽  
Serum Retinol ◽  
Cross Sectional ◽  
Displaced Populations ◽  
Adolescent Refugees

AbstractObjectiveTo investigate the prevalence of anaemia (haemoglobin < 11.0 to 13.0 g dl−1depending on age and sex group), iron deficiency (transferrin receptor concentration > 8.3 μg ml−1) and vitamin A deficiency (serum retinol < 0.7 μmoll−1) in adolescent refugees.DesignCross-sectional surveys.SettingKakuma refugee camp in Kenya and seven refugee camps in Nepal.SubjectsAdolescent refugee residents in these camps.ResultsAnaemia was present in 46% (95% confidence interval (CI): 42–51) of adolescents in Kenya and in 24% (95% CI: 20–28) of adolescents in Nepal. The sensitivity of palmar pallor in detecting anaemia was 21%. In addition, 43% (95% CI: 36–50) and 53% (95% CI: 46–61) of adolescents in Kenya and Nepal, respectively, had iron deficiency. In both surveys, anaemia occurred more commonly among adolescents with iron deficiency. Vitamin A deficiency was found in 15% (95% CI: 10–20) of adolescents in Kenya and 30% (95% CI: 24–37) of adolescents in Nepal. Night blindness was not more common in adolescents with vitamin A deficiency than in those without vitamin A deficiency. In Kenya, one of the seven adolescents with Bitot's spots had vitamin A deficiency.ConclusionsAnaemia, iron deficiency and vitamin A deficiency are common among adolescents in refugee populations. Such adolescents need to increase intakes of these nutrients; however, the lack of routine access makes programmes targeting adolescents difficult. Adolescent refugees should be considered for assessment along with other at-risk groups in displaced populations.

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