Nannizzia persicolor. [Descriptions of Fungi and Bacteria].

1980 ◽  
Author(s):  
P. M. Stockdale
Keyword(s):  
Geographical Distribution ◽  
Deer Mouse ◽  
Common Shrew ◽  
Wood Mouse ◽  
Clethrionomys Glareolus ◽  
Tinea Unguium ◽  
Inflammatory Lesions ◽  
The Face ◽  
Nannizzia Persicolor

Abstract A description is provided for Nannizzia persicolor. Information is included on the disease caused by the organism, its transmission, geographical distribution, and hosts. HOSTS: The primary hosts of N. persicolor are various species of voles (particularly the bank vole, Clethrionomys glareolus), on which it usually occurs without visible signs of infection (RMVM 6, 927), males being somewhat more frequently infected than females (RMVM 12, 157; 14, 1479). It is also sometimes carried on the fur of other rodents (recorded from pipistrelle bat (RMVM 5, 2201), hamster (RMVM 12, 157), deer mouse (RMVM 14, 134), wood mouse (RMVM 6, 926), common shrew (RMVM 6, 926) and weasel (RMVM 7, 63)) without apparent infection, and has been isolated from a healthy pony (RMVM 8, 446). Ringworm caused by this species has also been recorded in the dog (RMVM 2, 1650; 6, 1920; 12, 1854), horse (RMVM 6, 3213) and man. The epidemic in guineapigs in Tunisia (RMVM 5, 498) was probably not due to N. persicolor (RMVM 5, 2201). The guineapig, monkey, mouse and rabbit have been infected experimentally (RMVM 1, 1739; 10, 595). It has also been isolated on a few occasions from soil (RMVM 11, 95). DISEASE: Ringworm (dermatophytosis, tinea). In the vole the most constantly infected site is the tail, which may show varying degrees of scaling and hair loss, symptoms also sometimes found on fungus-free tails (6, 927); lesions have been found only rarely on other sites. In man infection occurs mainly on exposed parts of the glabrous skin, i.e. on the face, hands (tinea manuum) and forearms and lower legs (tinea corporis). Infections of the beard area (tinea barbae), nails (tinea unguium), scalp (tinea capitis) and feet (tinea pedis) have also been recorded [see NOTES]. Lesions are scaling and usually mildly to moderately erythematous. More inflammatory lesions may occur and kerion formation has been reported in a few instances. Hair is not invaded in vivo. GEOGRAPHICAL DISTRIBUTION: Possibly worldwide; N. persicolor has been recorded widely in Europe and rarely from N. America (Canada, USA), S. America (Brazil, Uruguay), Africa (Tunisia, S. Africa) and Asia (India, Israel) [see NOTES].

scholarly journals PCR Detection of Granulocytic Ehrlichiae in Ixodes ricinus Ticks and Wild Small Mammals in Western Switzerland

2000 ◽  
Vol 38 (3) ◽  
pp. 1002-1007 ◽  
Author(s):  
Jorge S. Liz ◽  
Laurence Anderes ◽  
John W. Sumner ◽  
Robert F. Massung ◽  
Lise Gern ◽  
...  
Keyword(s):  
Ixodes Ricinus ◽  
Small Mammals ◽  
Common Shrew ◽  
Wood Mouse ◽  
Clethrionomys Glareolus ◽  
Rrna Gene ◽  
Questing Ticks ◽  
Ixodes Ricinus Ticks ◽  
High Degree ◽  
Dual Infections

The presence of granulocytic ehrlichiae was demonstrated by PCR inIxodes ricinus ticks and wild small mammals in Switzerland in two areas of endemicity for bovine ehrlichiosis. Six ticks (three females and three nymphs) (1.4%) of 417 I. ricinus ticks collected by flagging vegetation contained ehrlichial DNA. A total of 201 small mammals from five species, wood mouse (Apodemus sylvaticus), yellow-necked mouse (Apodemus flavicollis), earth vole (Pitymys subterraneus), bank vole (Clethrionomys glareolus), and common shrew (Sorex araneus), were trapped. The analysis of I. ricinus mammals collected on 116 small mammals showed that nine C. glareolus voles and two A. sylvaticus mice hosted infected tick larvae. In these rodents, granulocytic ehrlichia infection was also detected in blood, spleen, liver, and ear samples. Further examinations of 190 small mammals without ticks or with noninfected ticks showed the presence of ehrlichial DNA in spleen and other tissues from six additional C. glareolus, three A. flavicollis, and one S. araneus mammals. This study suggests thatA. sylvaticus, A. flavicollis, S. araneus, and particularly C. glareolus are likely to be natural reservoirs for granulocytic ehrlichiae. Partial 16S rRNA gene sequences of granulocytic ehrlichiae from ticks and rodents showed a high degree of homology (99 to 100%) with granulocytic ehrlichiae isolated from humans. In contrast, groESL heat shock operon sequence analysis showed a strong divergence (approximately 5%) between the sequences in samples derived from rodents and those derived from samples from questing ticks or from other published ehrlichia sequences. Dual infections with granulocytic ehrlichia andBorrelia burgdorferi were found in ticks and small mammals.

Trichophyton violaceum. [Descriptions of Fungi and Bacteria].

1980 ◽  
Author(s):  
P. M. Stockdale
Keyword(s):  
Middle East ◽  
Lymph Nodes ◽  
Geographical Distribution ◽  
Tinea Capitis ◽  
Tinea Corporis ◽  
Tinea Unguium ◽  
Inflammatory Lesions ◽  
Trichophyton Violaceum ◽  
Tinea Barbae ◽  
Subcutaneous Tissues

Abstract A description is provided for Trichophyton violaceum. Information is included on the disease caused by the organism, its transmission, geographical distribution, and hosts. HOSTS: Primarily a pathogen of man (causing mycoses). Also recorded from buffalo, cat, cattle, dog and mouse (RMVM 6, 3187; 10, 505). The cat, dog, guineapig, monkey and mouse have been infected experimentally. The horse, fowl and pigeon have been implicated as hosts of T. violaceum. DISEASE: Ringworm (dermatophytosis, tinea). The scalp (tinea capitis), beard (tinea barbae), body (tinea corporis) and nails (tinea unguium, onychomycosis) may be infected. Infected hairs show an endothrix type of invasion and do not fluoresce under Wood's light. The hairs may break and curl producing 'black dots' on the scalp (also sometimes produced by other endothrix Trichophyton species). Inflammatory lesions (occasionally with the development of kerion), scarring and alopecia and, occasionally, favus-like lesions may occur. Infections of the subcutaneous tissues, lymph nodes, brain, bones and other internal tissues have been reported (RMVM 3, 1441; 4, 716; 9, 677; 11, 708; 12, 1847; 13, 961, 1572). GEOGRAPHICAL DISTRIBUTION: Worldwide. A dominant cause of scalp ringworm in S. and E. Europe, the Middle East, N. Africa, parts of Central and E. Africa, S. Africa and Asia (RMVM 10, 602; 13, 1558).

Epidermophyton floccosum. [Descriptions of Fungi and Bacteria].

1980 ◽  
Author(s):  
P. M. Stockdale
Keyword(s):  
Geographical Distribution ◽  
Tinea Pedis ◽  
Tinea Capitis ◽  
Skin Lesions ◽  
The Body ◽  
Epidermophyton Floccosum ◽  
Tinea Unguium ◽  
Tinea Cruris ◽  
Hen’S Egg

Abstract A description is provided for Epidermophyton floccosum. Information is included on the disease caused by the organism, its transmission, geographical distribution, and hosts. HOSTS: Primarily a pathogen of man (causing mycoses). Also recorded from dog (RMVM 6, 1920) and mouse (RMVM 6, 639). Animal inoculation is rarely successful; the guineapig (RMVM 14, 804), monkey (RMVM 1, 182) and the chorio-allantoic membrane of the hen's egg (RMVM 2, 1676; 4, 82) have been infected experimentally. DISEASE: Ringworm (dermatophytosis, tinea). The groin (tinea cruris, eczema marginatum, dobie itch) and feet (tinea pedis) are most frequently infected. The body (tinea corporis), hands (tinea manuum) and nails (onychomycosis, tinea unguium) may also be infected. Infections of the scalp (tinea capitis) are rare and the hair is never invaded in vivo. Skin lesions are scaling and erythematous, well-marginated with minute vesicopapules in the border. GEOGRAPHICAL DISTRIBUTION: Worldwide.

Microsporum canis. [Descriptions of Fungi and Bacteria].

1965 ◽  
Author(s):  
P. M. Stockdale
Keyword(s):  
Geographical Distribution ◽  
Tinea Capitis ◽  
Skin Lesions ◽  
The Body ◽  
Microsporum Canis ◽  
Seasonal Incidence ◽  
Tinea Unguium ◽  
The Face ◽  
Infection Disease ◽  
Bright Green

Abstract A description is provided for Microsporum canis. Information is included on the disease caused by the organism, its transmission, geographical distribution, and hosts. HOSTS: Primarily a pathogen of the cat and dog, frequently transmitted to man. Also recorded from the chimpanzee, chinchilla, fox, lion, monkey, pig, rabbit, sheep and tiger. Experimental animals are susceptible to infection. DISEASE: Ringworm (dermatophytosis, tinea). Infected hairs and animal claws usually fluoresce bright green under Wood's light and hairs are surrounded by ectothrix sheaths of small spores in a mosaic arrangement. In cats the lesions are usually inconspicuous. They may occur on any part of the body, but particularly the face and paws, and the whiskers and claws may be involved. In dogs infection is more noticeable, and is characterized by small circular areas of scaling and alopecia, sometimes with oedema and crust formation, on any part of the body. The claws may also be infected. Infections in dogs have a well defined seasonal incidence with a peak in Oct. -Feb., but the incidence in cats is poorly defined (Kaplan & Ivens, Sabouraudia 1: 91-102, 1961). In man the scalp (tinea capitis), glabrous skin (tinea corporis), and rarely the beard (tinea barbae), foot (tinea pedis) and nails (tinea unguium, onychomycosis) may be infected (mycoses). Children are most susceptible, particularly to scalp infection which is very rare in adults. Scalp lesions are scaling, inflammatory areas containing broken hairs or with total hair loss. Pustulation and kerion formation are not uncommon. Skin lesions are circinate, with a scaling centre and vesicular border. Kligman (RMVM 1, 2510; 2, 2484) studied the pathogenesis of tinea capitis caused by M. canis. GEOGRAPHICAL DISTRIBUTION: Africa (Algeria, Angola, Cape Verde Islands, Egypt, French W. Africa, Sahara, Tunisia, Union of S. Africa); Asia (Ceylon, India, Philippines, Turkey); Australasia & Oceania (Australia (N.S.W.), New Zealand); Europe, North America, Central America and West Indies (Costa Rica, Cuba, Guatemala, Mexico, Panama, Puerto Rico); South America (Argentina, Brazil (south of Pernambuco), Chile, Colombia, Ecuador, Peru, Uruguay, Venezuela).

Molecular basis of adaptive evolution of sperm motility involved in in vivo fertilization of terrestrial animals

Impact ◽  
2020 ◽  
Vol 2020 (6) ◽  
pp. 73-75
Author(s):  
Akihiko Watanabe
Keyword(s):  
Sexual Reproduction ◽  
Sperm Motility ◽  
Asexual Reproduction ◽  
Acrosome Reaction ◽  
Sperm Morphology ◽  
Adaptive Potential ◽  
Selective Pressures ◽  
The Face ◽  
Genetic Profiles

One of the unifying traits of life on this planet is reproduction, or life's ability to make copies of itself. The mode of reproduction has evolved over time, having almost certainly begun with simple asexual reproduction when the ancestral single celled organism divided into two. Since these beginnings' life has tried out numerous strategies, and perhaps one of the most important and successful has been sexual reproduction. This form of reproduction relies on the union of gametes, otherwise known as sperm and egg. Evolutionarily, sexual reproduction allows for greater adaptive potential because the genes of two unique individuals have a chance to recombine and mix in order to produce a new individual. Unlike asexual reproduction which produces genetically-identical clones of the parent individual, sex produces offspring with novel genes and combinations of genes. Therefore, in the face of new selective pressures there is a higher chance that one of these novel genetic profiles will produce an adaptation that is advantageous in the new circumstances. Dr Akihiko Watanabe is a reproductive biologist based in the Department of Biology, Faculty of Science Yamagata University in Japan, he is currently working on three research projects; a comparative study on the signalling pathways for inducing sperm motility and acrosome reaction in amphibians, the mechanism behind the adaptive modification of sperm morphology and motility, and the origin of sperm motility initiating substance (SMIS).

scholarly journals Antibacterial and In Vivo Studies of a Green, One-Pot Preparation of Copper/Zinc Oxide Nanoparticle-Coated Bandages

Membranes ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 462
Author(s):  
Archana R. Deokar ◽  
Ilana Perelshtein ◽  
Melissa Saibene ◽  
Nina Perkas ◽  
Paride Mantecca ◽  
...  
Keyword(s):  
Zinc Oxide ◽  
Metal Oxide ◽  
Ultrasound Irradiation ◽  
Face Mask ◽  
In Vivo Studies ◽  
One Pot ◽  
The Face ◽  
Bulk Scale ◽  
Particle Size And Shape

Simultaneous water and ethanol-based synthesis and coating of copper and zinc oxide (CuO/ZnO) nanoparticles (NPs) on bandages was carried out by ultrasound irradiation. High resolution-transmission electron microscopy demonstrated the effects of the solvent on the particle size and shape of metal oxide NPs. An antibacterial activity study of metal-oxide-coated bandages was carried out against Staphylococcus aureus (Gram-positive) and Escherichia coli (Gram-negative). CuO NP-coated bandages made from both water and ethanol demonstrated complete killing of S. aureus and E. coli bacteria within 30 min., whereas ZnO NP-coated bandages demonstrated five-log reductions in viability for both kinds of bacteria after 60 min of interaction. Further, the antibacterial mechanism of CuO/ZnO NP-coated bandages is proposed here based on electron spin resonance studies. Nanotoxicology investigations were conducted via in vivo examinations of the effect of the metal-oxide bandages on frog embryos (teratogenesis assay—Xenopus). The results show that water-based coatings resulted in lesser impacts on embryo development than the ethanol-based ones. These bandages should therefore be considered safer than the ethanol-based ones. The comparison between the toxicity of the metal oxide NPs prepared in water and ethanol is of great importance, because water will replace ethanol for bulk scale synthesis of metal oxide NPs in commercial companies to avoid further ignition problems. The novelty and importance of this manuscript is avoiding the ethanol in the typical water:ethanol mixture as the solvent for the preparation of metal oxide NPs. Ethanol is ignitable, and commercial companies are trying the evade its use. This is especially important these days, as the face mask produced by sonochemistry (SONOMASK) is being sold all over the world by SONOVIA, and it is coated with ZnO.

CD200 is a novel p53-target gene involved in apoptosis-associated immune tolerance

Blood ◽  
2004 ◽  
Vol 103 (7) ◽  
pp. 2691-2698 ◽  
Author(s):  
Michael D. Rosenblum ◽  
Edit Olasz ◽  
Jeffery E. Woodliff ◽  
Bryon D. Johnson ◽  
Marja C. Konkol ◽  
...  
Keyword(s):  
Target Gene ◽  
Molecular Mechanisms ◽  
Apoptotic Cell ◽  
Immune Reactivity ◽  
Biochemical Processes ◽  
The Face ◽  
P53 Target Gene ◽  
Self Antigens

Abstract During apoptotic cell death, biochemical processes modify self-proteins and create potential autoantigens. To maintain self-tolerance in the face of natural cell turnover, the immune system must prevent or control responses to apoptosis-associated autoantigens or risk autoimmunity. The molecular mechanisms governing this process remain largely unknown. Here, we show that expression of the immunoregulatory protein CD200 increases as murine dendritic cells (DCs) undergo apoptosis. We define CD200 as a p53-target gene and identify both p53- and caspase-dependent pathways that control CD200 expression during apoptosis. CD200 expression on apoptotic DCs diminishes proinflammatory cytokine production in response to self-antigens in vitro and is required for UVB-mediated tolerance to haptenated self-proteins in vivo. Up-regulation of CD200 may represent a novel mechanism, whereby immune reactivity to apoptosis-associated self-antigens is suppressed under steady state conditions. (Blood. 2004;103: 2691-2698)

Individualised Homeopathic Treatment of Acne—An Analysis of 83 Patients

Homeopathy ◽  
2021 ◽  
Author(s):  
Lawrence Chukwudi Nwabudike
Keyword(s):  
Inflammatory Lesions ◽  
Severe Acne ◽  
Homeopathic Medicine ◽  
Results Of Treatment ◽  
Therapeutic Guidelines ◽  
Acne Therapy ◽  
The Face ◽  
Pre Treatment ◽  
Lost To Follow Up

Abstract Background Acne is a common disorder of the pilosebaceous follicle. The face, back and chest are usually involved. It leads to significant diminution in quality of life. Numerous treatments are documented in therapeutic guidelines. Naturopathic approaches have been proposed in some, but the role of homeopathy is not examined. Methods In this study, 83 patients treated for acne with individualised homeopathic medicine alone were reviewed. Most had received conventional acne treatment, with limited success prior to presentation for homeopathy. Each patient was prescribed a single homeopathic medicine and followed up at 6- to 8-week intervals. The individualisation process resulted in 17 different medicines being used in this group. Photographic documentation was obtained per patient, with informed consent. Patients were classified as mild (comedonal acne with no papules or pustules), moderate (inflammatory and non-inflammatory lesions) and severe (predominantly inflammatory lesions: pustules, cysts, nodules). Results of treatment were recorded as remission (decrease in new lesion number, duration and intensity), failure to respond, and lost to follow-up (LTF). Results The average age of patients was 21.5 years (range 11–45 years). The F:M ratio was 55 (66.3%):28 (33.7%). Average pre-treatment duration was 5.5 years (0.25–22 years). Seven (8.4%) patients had mild acne, 37 (44.6%) moderate, and 39 (47%) severe acne. There were 13 (15.7%) LTFs, two (2.4%) failed to respond, and 68 (81.9%) went into remission. Average time to remission was 1.9 months (range 1.5–6 months), with no relapses or side-effects. The most commonly prescribed medicines were Lycopodium (38.6%), Palladium (15.7%) and Platinum (12.1%). Conclusion Individualised homeopathy may be useful for acne therapy. The most useful medicines appeared to be Lycopodium, Palladium and Platinum, though 17 different medicines were used in this study, underscoring the value of individualisation of therapy, a key characteristic of homeopathy.

scholarly journals Development and Characterization of a Sin Nombre Virus Transmission Model in Peromyscus maniculatus

Viruses ◽  
2019 ◽  
Vol 11 (2) ◽  
pp. 183 ◽  
Author(s):  
Bryce Warner ◽  
Derek Stein ◽  
Bryan Griffin ◽  
Kevin Tierney ◽  
Anders Leung ◽  
...  
Keyword(s):  
Peromyscus Maniculatus ◽  
Deer Mouse ◽  
Virus Transmission ◽  
Transmission Model ◽  
Deer Mice ◽  
Sin Nombre Virus ◽  
Infection Model ◽  
Main Driver ◽  
Heat Shock Responses

In North America, Sin Nombre virus (SNV) is the main cause of hantavirus cardiopulmonary syndrome (HCPS), a severe respiratory disease with a fatality rate of 35–40%. SNV is a zoonotic pathogen carried by deer mice (Peromyscus maniculatus), and few studies have been performed examining its transmission in deer mouse populations. Studying SNV and other hantaviruses can be difficult due to the need to propagate the virus in vivo for subsequent experiments. We show that when compared with standard intramuscular infection, the intraperitoneal infection of deer mice can be as effective in producing SNV stocks with a high viral RNA copy number, and this method of infection provides a more reproducible infection model. Furthermore, the age and sex of the infected deer mice have little effect on viral replication and shedding. We also describe a reliable model of direct experimental SNV transmission. We examined the transmission of SNV between deer mice and found that direct contact between deer mice is the main driver of SNV transmission rather than exposure to contaminated excreta/secreta, which is thought to be the main driver of transmission of the virus to humans. Furthermore, increases in heat shock responses or testosterone levels in SNV-infected deer mice do not increase the replication, shedding, or rate of transmission. Here, we have demonstrated a model for the transmission of SNV between deer mice, the natural rodent reservoir for the virus. The use of this model will have important implications for further examining SNV transmission and in developing strategies for the prevention of SNV infection in deer mouse populations.

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