scholarly journals Prospective evaluation of lactose malabsorption by lactose hydrogen breath test in individuals infected with and passing cystsEntamoeba histolytica

2004 ◽  
Vol 92 (2) ◽  
pp. 207-208 ◽  
Author(s):  
Satya Vati Rana ◽  
Deepak Kumar Bhasin ◽  
Virender Kumar Vinayak

The aim of the present prospective study was to detect lactose malabsorption in subjects in northern India infected with Entamoeba histolytica and passing cysts. The study group included forty-one patients with E. histolytica cysts in at least one of three consecutive faecal samples. Lactose malabsorption was detected by a lactose H2 breath test. The results were compared with those of forty controls subjects. Thirty-two of forty-one (78·0%) subjects passing E. histolytica cysts had lactose malabsorbtion compared with seventeen of forty (42·5%) control subjects (P>0·01). In conclusion, the present study shows that lactose malabsorption is significantly more common in individuals infected with E. histolytica and passing cysts compared with control subjects.

2004 ◽  
Vol 144 (6) ◽  
pp. 313-318 ◽  
Author(s):  
Michele Di Stefano ◽  
Antonio Missanelli ◽  
Emanuela Miceli ◽  
Alessandra Strocchi ◽  
Gino Roberto Corazza

2006 ◽  
Vol 20 (4) ◽  
pp. 265-268 ◽  
Author(s):  
Mauro Di Camillo ◽  
Vanessa Marinaro ◽  
Fiorenza Argnani ◽  
Tiziana Foglietta ◽  
Piero Vernia

BACKGROUND: The hydrogen breath test (H2BT) is the most widely used procedure in the diagnostic workup of lactose malabsorption and lactose intolerance.AIM: To establish whether a simplified two-or three-sample test may reduce time, costs and staff resources without reducing the sensitivity of the procedure.PATIENTS AND METHODS: Data from 1112 patients (292 men, 820 women) with a positive 4 h, nine-sample H2BT were retrospectively analyzed. Patients were stratified according to the degree of lactose malabsorption, the occurrence and type of symptoms. Loss of sensitivity in the procedure was evaluated taking into account two-sample tests (0 min and 120 min or 0 min and 210 min) or three-sample tests (0 min, 120 min and 180 min or 0 min, 120 min and 210 min).RESULTS: Using a two-sample test (0 min and 120 min or 0 min and 210 min) the false-negative rate was 33.4% and 22.7%, respectively. With a three-sample test (0 min, 120 min and 180 min or 0 min, 120 min or 210 min), lactose malabsorption was diagnosed in 91.2% (1014 of 1112) patients and in 96.1% (1068 of 1112) patients, respectively. Of 594 patients with abdominal symptoms, 158 (26.6%) and 73 (12.2%) would have false-negative results with 0 min and 120 min or 0 min and 210 min two-sample tests, respectively. The three-sample tests, 0 min, 120 min and 180 min or 0 min, 120 min and 210 min, have a false-negative rate of 5.9% and 2.1%, respectively.CONCLUSIONS: A three-sample H2BT is time-and cost-sparing without significant loss of sensitivity for the diagnosis both of lactose malabsorption and lactose intolerance.


2009 ◽  
Vol 41 (7) ◽  
pp. 474-479 ◽  
Author(s):  
M. Di Stefano ◽  
V. Terulla ◽  
P. Tana ◽  
S. Mazzocchi ◽  
E. Romero ◽  
...  

2003 ◽  
Vol 124 (4) ◽  
pp. A191-A192
Author(s):  
Juergen R.A. Barnert ◽  
Jochen Weymayer ◽  
Jeannette Fischer ◽  
Jochen Pischel ◽  
Helmut Messmann

Sign in / Sign up

Export Citation Format

Share Document