scholarly journals Circulating ‘big’ insulin in protein-energy malnutrition

1973 ◽  
Vol 30 (2) ◽  
pp. 345-350 ◽  
Author(s):  
Dorothy J. Becker ◽  
Penelope J. Murray ◽  
J. D. L. Hansen ◽  
B. L. Pimstone
Keyword(s):  
Protein Energy Malnutrition ◽  
Significant Negative Correlation ◽  
Insulin Content ◽  
Immunoreactive Insulin ◽  
Total Body Potassium ◽  
Intravenous Injections ◽  
Protein Energy ◽  
Total Body ◽  
Total Iri ◽  
Wide Fluctuation

1. The ‘big’ insulin content of the serums from ten children with protein–energy malnutrition was estimated before, during and after 3–6 weeks of treatment. The values for immunoreactive insulin (IRI) after intravenous injections of glucose were almost normal, with one exception, although tolerance was impaired. In addition, total body potassium content (TBK) was measured for three of the children on each test day.2. In nine of twenty-three estimations ‘big’ insulin content was slightly more than 20% of the total IRI. However, there was a wide fluctuation in the values and no change was noted after treatment.3. The amount of ‘big’ insulin did not correlate with either the magnitude of insulin secretion, the insulin:glucose ratio or TBK. There was a barely significant negative correlation between ‘big’ insulin content and degree of glucose intolerance, with some individual exceptions.

scholarly journals Potassium supplementation, serum immunoreactive insulin concentrations and glucose tolerance in protein-energy malnutrition

1975 ◽  
Vol 33 (1) ◽  
pp. 55-61 ◽  
Author(s):  
M. D. Mann ◽  
Dorothy J. Becker ◽  
B. L. Pimstone ◽  
J. D. L. Hansen
Keyword(s):  
Considerable Increase ◽  
Protein Energy Malnutrition ◽  
Immunoreactive Insulin ◽  
Potassium Depletion ◽  
High Potassium ◽  
Intravenous Glucose ◽  
Potassium Intake ◽  
Serum Immunoreactive Insulin ◽  
Protein Energy ◽  
Impaired Insulin

1. The serum immunoreactive insulin (IRI) concentrations, and glucose disappearance rate-constants after intravenous glucose administration were measured on admission and during recovery in children suffering from protein-energy malnutrition (PEM).2. A high potassium intake resulted in a considerable increase in the serum IRI levels early in the treatment period. There was a definite relationship between potassium depletion and many measurements of insulin secretion.3. The results are consistent with the hypothesis that impaired insulin release in children suffering from PEM is partly the result of potassium depletion.

IMPROVEMENT THE PROPERTIES OF YOGHURT USING LEGUMES TO THERAPY PROTEIN ENERGY MALNUTRITION

2018 ◽  
Vol 3 (5) ◽  
pp. 79-88
Author(s):  
Abtsam M.F. Badr ◽  
D.A.M. Amer ◽  
M.Y.A. El- Hawary ◽  
A.M.A. Naem
Keyword(s):  
Protein Energy Malnutrition ◽  
Protein Energy

scholarly journals Sarcopenic Obesity in Liver Cirrhosis: Possible Mechanism and Clinical Impact

2021 ◽  
Vol 22 (4) ◽  
pp. 1917
Author(s):  
Hiroki Nishikawa ◽  
Hirayuki Enomoto ◽  
Shuhei Nishiguchi ◽  
Hiroko Iijima
Keyword(s):  
Liver Cirrhosis ◽  
Current Knowledge ◽  
Protein Energy Malnutrition ◽  
Public Health Problem ◽  
Diagnostic Value ◽  
Sarcopenic Obesity ◽  
Important Public Health Problem ◽  
Alcoholic Fatty Liver ◽  
Protein Energy ◽  
Clinical Consequences

The picture of chronic liver diseases (CLDs) has changed considerably in recent years. One of them is the increase of non-alcoholic fatty liver disease. More and more CLD patients, even those with liver cirrhosis (LC), tend to be presenting with obesity these days. The annual rate of muscle loss increases with worsening liver reserve, and thus LC patients are more likely to complicate with sarcopenia. LC is also characterized by protein-energy malnutrition (PEM). Since the PEM in LC can be invariable, the patients probably present with sarcopenic obesity (Sa-O), which involves both sarcopenia and obesity. Currently, there is no mention of Sa-O in the guidelines; however, the rapidly increasing prevalence and poorer clinical consequences of Sa-O are recognized as an important public health problem, and the diagnostic value of Sa-O is expected to increase in the future. Sa-O involves a complex interplay of physiological mechanisms, including increased inflammatory cytokines, oxidative stress, insulin resistance, hormonal disorders, and decline of physical activity. The pathogenesis of Sa-O in LC is diverse, with a lot of perturbations in the muscle–liver–adipose tissue axis. Here, we overview the current knowledge of Sa-O, especially focusing on LC.

scholarly journals Dynamic Oral Texture Properties of Selected Indigenous Complementary Porridges Used in African Communities

Foods ◽  
2019 ◽  
Vol 8 (6) ◽  
pp. 221 ◽  
Author(s):  
James Makame ◽  
Tanita Cronje ◽  
Naushad M. Emmambux ◽  
Henriette De Kock
Keyword(s):  
Young Children ◽  
Low Income ◽  
Nutrient Intake ◽  
Control Method ◽  
Protein Energy Malnutrition ◽  
Public Health Problem ◽  
Major Public Health Problem ◽  
Texture Properties ◽  
Protein Energy ◽  
Infants And Young Children

Child malnutrition remains a major public health problem in low-income African communities, caused by factors including the low nutritional value of indigenous/local complementary porridges (CP) fed to infants and young children. Most African children subsist on locally available starchy foods, whose oral texture is not well-characterized in relation to their sensorimotor readiness. The sensory quality of CP affects oral processing (OP) abilities in infants and young children. Unsuitable oral texture limits nutrient intake, leading to protein-energy malnutrition. The perception of the oral texture of selected African CPs (n = 13, Maize, Sorghum, Cassava, Orange-fleshed sweet potato (OFSP), Cowpea, and Bambara) was investigated by a trained temporal-check-all-that-apply (TCATA) panel (n = 10), alongside selected commercial porridges (n = 19). A simulated OP method (Up-Down mouth movements- munching) and a control method (lateral mouth movements- normal adult-like chewing) were used. TCATA results showed that Maize, Cassava, and Sorghum porridges were initially too thick, sticky, slimy, and pasty, and also at the end not easy to swallow even at low solids content—especially by the Up-Down method. These attributes make CPs difficult to ingest for infants given their limited OP abilities, thus, leading to limited nutrient intake, and this can contribute to malnutrition. Methods to improve the texture properties of indigenous CPs are needed to optimize infant nutrient intake.

scholarly journals Study of NT-pro-BNP and Hs-Troponin I biomarkers for early detection of children’s heart function of protein-energy malnutrition

2019 ◽  
Vol 11 (2) ◽  
Author(s):  
Herlina Dimiati ◽  
Abdus Samik Wahab ◽  
Mohammad Juffrie ◽  
Madarina Julia ◽  
Basri A. Gani
Keyword(s):  
Troponin I ◽  
Heart Function ◽  
Protein Energy Malnutrition ◽  
Area Under The Curve ◽  
Left Ventricular ◽  
The Body ◽  
Chromatography Method ◽  
Blood Electrolytes ◽  
Ventricular Mass ◽  
Protein Energy

The Protein Energy Malnutrition (PEM) is the condition of a lack of carbohydrate and protein stores in the body that trigger chronic failure nutrient intake and body maintenance function caused to impact the heart functions. The NT-pro-BNP and Hs- Troponin I proteins were found as the indicator of cardiac dysfunction. The sixty subjects of PEM, analyzed by standard of Indonesia Healt Ministry as well as nutritional status. The blood electrolytes examined by laboratory assay and the levels of Hs-Troponin 1 and NT-Pro-BNP were analyzed by Immune-Chromatography method. Assessing of the ventricular mass with the seeing the peak of the diastolic flow rate of left ventricular that estimated by the curve of the receiver operating characteristic and the area under the curve (P<0.05). The result has shown that the PEM decreased in the left ventricular mass for impaired heart function and systolic disorder. The Hs- Troponin I (90.9%) has better sensitivity than NT-pro-BNP (85.5%) if the merger of those markers possesses the lowest sensitivity (81.8%). These proteins have good biomarkers in heart function, mainly in cases where PEM is present.

scholarly journals Faulty Breast Feeding Practice : A Risk Factor in Malnourished Children

2015 ◽  
Vol 14 (2) ◽  
pp. 43-47
Author(s):  
Sukhendu Shekhar Sen ◽  
Jhulan Das Sharma ◽  
Dhananjoy Das ◽  
Shahed Iqbal ◽  
Md Badruddoza
Keyword(s):  
Breast Feeding ◽  
Protein Energy Malnutrition ◽  
Control Group ◽  
Case Group ◽  
Feeding Practice ◽  
Prelacteal Feeding ◽  
College Hospital ◽  
Major Health Problem ◽  
Protein Energy ◽  
Breast Fed

Background: The predominant form of malnutrition is commonly called proteincalorie malnutrition. Protein Energy Malnutrition (PEM) is still a major health problem in children of developing countries including Bangladesh. The causes of malnutrition are multifactorial including nutritional factors, socioeconomic factors, health status of the mothers and repeated infections in children.Objective: To explore the information regarding the breast feeding practices of children suffering from Protein-Energy Malnutrition.Methods: This case control study was conducted in Chittagong Medical College Hospital from November 2006 to April 2007. A total of 65 controls and 65 cases were selected consecutively for the purpose of the study. Their mothers were interviewed with help of structured questionnaire containing all the variables of interest to attain the study objectives. The test statistics used to analyze the data were descriptive statistics and Chi-square (c2) or Fisher’s Exact Probability Test.Results: A significantly higher frequency of cases (67.7%) were given pre-lacteal feed, predominantly honey and sugar-water compared to control group (41.5%) (p = 0.008). Nearly 100% of controls were given colostrums compared to 75% of the cases. About one-third (31.3%) of the cases was exclusively breast-fed in comparison to 58.5% of the control group (p = 0.003). Over onequarter (27.7%) of the control were breast-fed upto 6 months of age, as opposed to only 1.5% cases (p < 0.001). Duration of predominant breast feeding for more than 6 months of age was also significantly higher in control group than that in case group (p = 0.001). Breast milk substitutes demonstrate their significant presence in cases (38.5%) than that in controls (9%) (p = 0.003).Conclusion: The study showed that rejection of colostrums, practice of prelacteal feeding, delayed initiation of breast feeding, early cessation of exclusive breast feeding and use of formula milk all were significantly higher in the malnourished group of children than those in their normal counterpart.Chatt Maa Shi Hosp Med Coll J; Vol.14 (2); Jul 2015; Page 43-47

Nutritional Status of Patients Undergoing Continuous Ambulatory Peritoneal Dialysis (CAPD)

1983 ◽  
Vol 3 (3) ◽  
pp. 138-141 ◽  
Author(s):  
Brigitte Heide ◽  
Andreas Pierratos ◽  
Ramesh Khanna ◽  
Jean Pettit ◽  
Raymond Ogilvie ◽  
...  
Keyword(s):  
Body Weight ◽  
Peritoneal Dialysis ◽  
Nutritional Status ◽  
Continuous Ambulatory Peritoneal Dialysis ◽  
Protein Intake ◽  
Biochemical Parameters ◽  
Total Body Potassium ◽  
Total Body ◽  
Over Time

Nutritional follow-up of 20 CAPD patients for 18–24 months showed a decrease in total body nitrogen, increase in total body potassium and body weight, and a decrease in protein intake over time. There was no correlation between changes in TBN and the biochemical parameters measured. Serial dietetic assessments and measurements of total body nitrogen as well as adherence to an adequate protein intake will assist in the prevention of malnutrition in CAPD patients.

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