scholarly journals “The bloodiness and horror of it”

2021 ◽  
Vol 11 (1) ◽  
pp. 1-22
Author(s):  
Stella Bullo
Keyword(s):  
Diagnosis Delay ◽  
Comprehensive Understanding ◽  
Online Forum ◽  
Metaphor Analysis ◽  
Conceptual Integration ◽  
Pain Experience ◽  
Naturally Occurring ◽  
Holistic Assessment ◽  
Gynaecological Disease ◽  
Popular Texts

Abstract In this work, I explore pain descriptions by women who live with the life-altering gynaecological disease of endometriosis. This condition causes incapacitating pain, which tends to be dismissed and normalised as part of the female condition (Cumberbatch, 2019). My aim is to explore the general patterns of pain conceptualisation by women with endometriosis and outline how an in-depth examination of salient elements of narrative scenarios may contribute towards providing a comprehensive understanding of the pain experience. I first examine patterns of metaphorical pain collocates from a corpus generated from online forum contributions. Following this, I explore metaphorical scenarios of pain, focusing on stories that reference popular texts or genres from a conceptual integration perspective. I argue that the combination of metaphor analysis of naturally-occurring data and conceptual intertextuality and interdiscursivity analysis in the metaphorical scenarios of elicited data constitute a methodological niche that allows a holistic assessment of the pain that can potentially be used in consultations and may help tackle the alarming diagnosis delay of endometriosis, which is currently 7.5 years.

Metaphorical propositions: a rationale

2002 ◽  
Vol 11 (1) ◽  
pp. 7-16 ◽  
Author(s):  
Peter Crisp
Keyword(s):  
Cognitive Processes ◽  
Conceptual Metaphor ◽  
Metaphor Analysis ◽  
Metaphorical Language ◽  
Cross Domain ◽  
Naturally Occurring ◽  
Domain Mapping ◽  
Work Done ◽  
Discourse Psychology ◽  
Linguistic Basis

This article is an overview of the approach to metaphor analysis expounded in the following three articles. Until now the study of conceptual metaphor has been based mainly on the evidence of invented linguistic examples. Although the great value of the work done within this framework is clear, a more empirically oriented approach will need to engage with metaphorical language in naturally occurring discourse. To study this an explicit analytic procedure is required. Although such a procedure should ultimately provide a new source of evidence for underlying cognitive processes, it will not provide a direct path from linguistic to cognitive reality. When our group classifies an instance of language as metaphorical we thus do not claim that it realizes a psychologically real conceptual metaphor, but only that it provides the linguistic basis for such a realization. In specifying the conceptual metaphorical potential of this linguistic basis, we have found the tools of propositional analysis, as developed by discourse psychology, as well as the concept of cross-domain mapping familiar in cognitive semantics, to be extremely useful. Our approach to metaphor analysis thus has three levels: that of metaphorical language; that of the metaphorical proposition; and that of the cross-domain mapping.

scholarly journals A National Online Forum on Ethnic Differences in Cancer Pain Experience

2009 ◽  
Vol 58 (2) ◽  
pp. 86-94 ◽  
Author(s):  
Eun-Ok Im ◽  
Seung Hee Lee ◽  
Yi Liu ◽  
Hyun-Ju Lim ◽  
Enrique Guevara ◽  
...  
Keyword(s):  
Cancer Pain ◽  
Ethnic Differences ◽  
Online Forum ◽  
Pain Experience

Formalizing contemporary conceptual metaphor theory

2016 ◽  
Vol 8 (2) ◽  
pp. 166-213 ◽  
Author(s):  
Elise Stickles ◽  
Oana David ◽  
Ellen K. Dodge ◽  
Jisup Hong
Keyword(s):  
Internal Structure ◽  
Conceptual Metaphor ◽  
Construction Grammar ◽  
Data Driven ◽  
Metaphor Analysis ◽  
Conceptual Metaphor Theory ◽  
Naturally Occurring ◽  
Metaphor Theory ◽  
Data Driven Approach ◽  
Hierarchical Nature

This paper describes an innovative formalization of Conceptual Metaphor Theory and its implementation in a structured metaphor repository. Central to metaphor analysis is the development of an internal structure of frames and relations between frames, based on an Embodied Construction Grammar framework, which then informs the structure of metaphors and relationships between metaphors. The hierarchical nature of metaphors and frames is made explicit, such that inferential information originating in embodied conceptual primitives is inherited throughout the network. The present analysis takes a data-driven approach, where lexical differences in linguistic expressions attested in naturally-occurring discourse lead to a continued refinement and expansion of our analyses.

scholarly journals Exploring disempowerment in women’s accounts of endometriosis experiences

2018 ◽  
Vol 12 (6) ◽  
pp. 569-586 ◽  
Author(s):  
Stella Bullo
Keyword(s):  
Coping Strategies ◽  
Social Environment ◽  
Corpus Analysis ◽  
Macro Level ◽  
Online Forum ◽  
Language Choices ◽  
Micro Level ◽  
Communication Practices ◽  
Analytical Tools ◽  
Gynaecological Disease

This work explores disempowerment caused by discourses surrounding the life-altering gynaecological disease of endometriosis. Despite affecting one in 10 women, the worldwide average diagnosis time is 7.5 years, and it is mainly diagnosed when exploring infertility rather than complaints about incapacitating pain and other associated manifestations. The aim of this article is to identify dis/empowerment caused by discourses in the healthcare and social environment of women as manifested in their accounts of endometriosis experiences. Having been informed and shaped by a corpus analysis of online forum data, this work explores accounts collected through interviews with women who have endometriosis using discourse analytical tools. Through an examination of the dialectics between micro-level language choices inscribing agency, or lack of, and macro-level discourses in the contexts in which women interact, the findings indicate that disempowerment is mostly a consequence of the perceived lack of agency over achieving diagnosis and knowledge of the condition in order to understand and learn coping strategies. The article concludes with implications for endometriosis communication practices and suggestions for broader enquiries in the field.

Pathology of Bone Cells in Pigs with Experimental Turbinate Osteoporosis (Atrophic Rhinitis)

1971 ◽  
Vol 29 ◽  
pp. 304-305
Author(s):  
A. W. Fetter ◽  
C. C. Capen
Keyword(s):  
Mucous Membrane ◽  
Bone Cells ◽  
Atrophic Rhinitis ◽  
Infectious Agents ◽  
Metabolic Disturbances ◽  
Progressive Reduction ◽  
Naturally Occurring ◽  
Fundamental Cause ◽  
Osteocytic Osteolysis ◽  
Uncertain Etiology

Atrophic rhinitis in swine is a disease of uncertain etiology in which infectious agents, hereditary predisposition, and metabolic disturbances have been reported to be of primary etiologic importance. It shares many similarities, both clinically and pathologically, with ozena in man. The disease is characterized by deformity and reduction in volume of the nasal turbinates. The fundamental cause for the localized lesion of bone in the nasal turbinates has not been established. Reduced osteogenesis, increased resorption related to inflammation of the nasal mucous membrane, and excessive resorption due to osteocytic osteolysis stimulated by hyperparathyroidism have been suggested as possible pathogenetic mechanisms.The objectives of this investigation were to evaluate ultrastructurally bone cells in the nasal turbinates of pigs with experimentally induced atrophic rhinitis, and to compare these findings to those in control pigs of the same age and pigs with the naturally occurring disease, in order to define the fundamental lesion responsible for the progressive reduction in volume of the osseous core.

High Resolution Replication of Organoclay Surfaces

1982 ◽  
Vol 40 ◽  
pp. 576-577
Author(s):  
W. W. Barker ◽  
W. E. Rigsby ◽  
V. J. Hurst ◽  
W. J. Humphreys
Keyword(s):  
Clay Mineral ◽  
Organic Molecule ◽  
Organic Molecules ◽  
X Ray Diffraction ◽  
Xrd Pattern ◽  
X Ray ◽  
Naturally Occurring ◽  
Silicate Layers ◽  
Mineral Identification

Experimental clay mineral-organic molecule complexes long have been known and some of them have been extensively studied by X-ray diffraction methods. The organic molecules are adsorbed onto the surfaces of the clay minerals, or intercalated between the silicate layers. Natural organo-clays also are widely recognized but generally have not been well characterized. Widely used techniques for clay mineral identification involve treatment of the sample with H2 O2 or other oxidant to destroy any associated organics. This generally simplifies and intensifies the XRD pattern of the clay residue, but helps little with the characterization of the original organoclay. Adequate techniques for the direct observation of synthetic and naturally occurring organoclays are yet to be developed.

SEM study of the morphological effects of kinetin and zeatin on the growth and development of the apical meristem in wheat

1995 ◽  
Vol 53 ◽  
pp. 978-979
Author(s):  
G. M. Hutchins ◽  
J. S. Gardner
Keyword(s):  
Growth And Development ◽  
Furfuryl Alcohol ◽  
Apical Meristem ◽  
Plant Cells ◽  
Triticum Aestivum L ◽  
Morphological Development ◽  
Naturally Occurring ◽  
Chinese Spring Wheat ◽  
Sem Study ◽  
Moist Environment

Cytokinins are plant hormones that play a large and incompletely understood role in the life-cycle of plants. The goal of this study was to determine what roles cytokinins play in the morphological development of wheat. To achieve any real success in altering the development and growth of wheat, the cytokinins must be applied directly to the apical meristem, or spike of the plant. It is in this region that the plant cells are actively undergoing mitosis. Kinetin and Zeatin were the two cytokinins chosen for this experiment. Kinetin is an artificial hormone that was originally extracted from old or heated DNA. Kinetin is easily made from the reaction of adenine and furfuryl alcohol. Zeatin is a naturally occurring hormone found in corn, wheat, and many other plants.Chinese Spring Wheat (Triticum aestivum L.) was used for this experiment. Prior to planting, the seeds were germinated in a moist environment for 72 hours.

Fine structure and properties of defects in naturally occurring silicates and oxides

1990 ◽  
Vol 48 (4) ◽  
pp. 460-461
Author(s):  
David R. Veblen
Keyword(s):  
Chemical Reactions ◽  
High Resolution Electron Microscopy ◽  
Extended Defects ◽  
Single Chain ◽  
Naturally Occurring ◽  
Resolution Electron ◽  
Fine Structures ◽  
Image Simulations ◽  
Similar Crystal Structure

Extended defects and interfaces control many processes in rock-forming minerals, from chemical reactions to rock deformation. In many cases, it is not the average structure of a defect or interface that is most important, but rather the structure of defect terminations or offsets in an interface. One of the major thrusts of high-resolution electron microscopy in the earth sciences has been to identify the role of defect fine structures in reactions and to determine the structures of such features. This paper will review studies using HREM and image simulations to determine the structures of defects in silicate and oxide minerals and present several examples of the role of defects in mineral chemical reactions. In some cases, the geological occurrence can be used to constrain the diffusional properties of defects.The simplest reactions in minerals involve exsolution (precipitation) of one mineral from another with a similar crystal structure, and pyroxenes (single-chain silicates) provide a good example. Although conventional TEM studies have led to a basic understanding of this sort of phase separation in pyroxenes via spinodal decomposition or nucleation and growth, HREM has provided a much more detailed appreciation of the processes involved.

Flavonoids in adipose tissue inflammation and atherosclerosis: one arrow, two targets

2020 ◽  
Vol 134 (12) ◽  
pp. 1403-1432 ◽  
Author(s):  
Manal Muin Fardoun ◽  
Dina Maaliki ◽  
Nabil Halabi ◽  
Rabah Iratni ◽  
Alessandra Bitto ◽  
...  
Keyword(s):  
Adipose Tissue ◽  
Fruits And Vegetables ◽  
Metabolic Diseases ◽  
Therapeutic Agents ◽  
Adipose Tissue Inflammation ◽  
Cellular Mechanisms ◽  
Tissue Inflammation ◽  
Cholesterol Levels ◽  
Naturally Occurring ◽  
Pro Inflammatory Cytokines

Abstract Flavonoids are polyphenolic compounds naturally occurring in fruits and vegetables, in addition to beverages such as tea and coffee. Flavonoids are emerging as potent therapeutic agents for cardiovascular as well as metabolic diseases. Several studies corroborated an inverse relationship between flavonoid consumption and cardiovascular disease (CVD) or adipose tissue inflammation (ATI). Flavonoids exert their anti-atherogenic effects by increasing nitric oxide (NO), reducing reactive oxygen species (ROS), and decreasing pro-inflammatory cytokines. In addition, flavonoids alleviate ATI by decreasing triglyceride and cholesterol levels, as well as by attenuating inflammatory mediators. Furthermore, flavonoids inhibit synthesis of fatty acids and promote their oxidation. In this review, we discuss the effect of the main classes of flavonoids, namely flavones, flavonols, flavanols, flavanones, anthocyanins, and isoflavones, on atherosclerosis and ATI. In addition, we dissect the underlying molecular and cellular mechanisms of action for these flavonoids. We conclude by supporting the potential benefit for flavonoids in the management or treatment of CVD; yet, we call for more robust clinical studies for safety and pharmacokinetic values.

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