Pæn, flot, dejlig, and lækker

2021 ◽  
Vol 8 (1) ◽  
Author(s):  
Carsten Levisen
Keyword(s):  
High Resolution ◽  
Aesthetic Experiences ◽  
Lexical Semantic ◽  
Shed Light

Abstract This paper examines the Danish language of aesthetics from the perspective of four untranslatable adjectives: pæn, flot, dejlig, and lækker. These words are frequent and salient in everyday discourses, and as such they shed light on Danish “folk” conceptions. From the perspective of Lexical Anthropology and NSM Semantics, each of the words are explored and explicated in order to shed light on the ways in which Danish discourse organize positive aesthetic experiences. Sensitive to polysemy, and the variety of lexicogrammatical frames in which the words occur, the paper provides a high-resolution analyses of the “something ADJ frame” which enables discourses of design, food, and art. Based on lexical semantic evidence, the paper locates two themes in Danish discourse: “aesthetic normality” and “ordinary hedonism” which seem to act as cognitive axes around which discourses revolve. The paper argues that words hold the key to understanding the diversity of aesthetic cultures, and that untranslatables in particular, allow for a deep emic understanding of how local configurations of seeing, feeling, touching, and thinking are constituted.

scholarly journals Identification of Protein Complexes Associated with the Usher Syndrome 2C and Epilepsy-Associated Protein VLGR1 Applying Affinity Proteomics

2017 ◽  
Vol 4 (1) ◽  
pp. 100051 ◽  
Author(s):  
Barbara Knapp ◽  
Deva Krupakar Kusuluri ◽  
Nicola Horn ◽  
Karsten Boldt ◽  
Marius Ueffing ◽  
...  
Keyword(s):  
High Resolution ◽  
Signaling Pathways ◽  
Protein Complexes ◽  
Usher Syndrome ◽  
Protein Networks ◽  
Cellular Compartments ◽  
Affinity Proteomics ◽  
Shed Light

Authors aimed to identify novel VLGR1-associated protein networks to shed light on its integration into signaling pathways and the cellular compartments in which VLGR1 functions using high-resolution affinity proteomics based on tandem affinity purifications (TAPs).

scholarly journals A Tale of Two Shitties

2020 ◽  
Vol 4 (2) ◽  
pp. 20-41
Author(s):  
William Robertson
Keyword(s):  
High Resolution ◽  
Data Collection ◽  
Cancer Prevention ◽  
Anal Cancer ◽  
Clinical Practices ◽  
The Everyday ◽  
Ethnographic Data ◽  
The Relationship ◽  
Shed Light ◽  
Prevention Clinic

Based on 12 months of ethnographic data collection in an anal cancer prevention clinic, this article uses the extreme examples of patients involuntarily defecating through the anoscope during the procedure to highlight the relationship between the extreme and the everyday. Despite the rarity of this occurrence, I argue that these extreme examples shed light on the ways the daily clinical routines are embodied as an expert habitus. High Resolution Anoscopy procedures are specialized, highly routinized practices that are performed hundreds of times per month at the clinic. These routines result in the development of a clinical habitus that guides physicians in deploying techniques to efficiently conduct the invasive examination. Exemplary examples of ordinary procedures certainly help explain how this expert habitus is enacted through routine clinical practices; however, this expertise becomes especially observable in moments when habituated practices are disrupted, forcing clinicians to react and respond in unscripted ways. I discuss the only two instances of patients defecating through the anoscope that occurred while conducting my research, each with a different clinician. These extreme examples provide rich opportunities to analyze how clinicians with similar procedural habits navigate extraordinary situations in expert and professional but idiosyncratic ways. Whereas exemplary examples of everyday routinized procedures can show the process of developing an expert clinical habitus, these extreme examples more clearly demonstrate how this habitus enacts expertise and professionalism by highlighting the clinicians’ abilities to deftly navigate the technical and sociocultural aspects of such extraordinary disruptions.

scholarly journals Animal remains from the Late Medieval kitchen of the Esztergom archdiocese, Hungary - the benefits of screening

Starinar ◽  
2021 ◽  
pp. 231-251
Author(s):  
Erika Gál ◽  
László Bartosiewicz
Keyword(s):  
High Resolution ◽  
Fish Farming ◽  
Taxonomic Diversity ◽  
Local Production ◽  
Resolution Recovery ◽  
Documentary Sources ◽  
15Th Century ◽  
Animal Remains ◽  
Animal Bone ◽  
Shed Light

Medieval animal remains from the Esztergom archbishopric (Hungary) were screened using 5 mm and 2 mm mesh sizes, aimed at the high-resolution study of fish and bird remains and helping to achieve better comparisons with documentary sources. This is the first medieval assemblage in Hungary recovered using screening. A total of 7,294 animal remains are studied here, representing the 14th and 15th century. The screening resulted in quantities of fish and bird bones. The large find numbers also multiplied the taxonomic diversity. In addition to the remains of new, small-bodied species, bones of young fish showed a diachronic increase in the contribution of carp and young pike to the diet. This seems consonant with the expansion of medieval fish farming. Remains of juvenile birds could also be identified. Some worked bones recovered by screening indicate the manufacturing or reparation of crossbows at the site. Thanks to these details, our material stands out among other contemporaneous animal bone assemblages from the Carpathian Basin. Comparisons between sites, however, must be done with caution, as our data are qualitatively different from others. Large bones of livestock and the near absence of those from large game may be interpreted in the light of other hand-collected samples, while fish and bird remains and even the abundance of brown hare need to be seen in part as a product of high-resolution recovery. The newly discovered spectrum of animal remains could be profitably interpreted in the light of late 15th century accounting books of the archbishop. Although these documentary sources slightly post-date our material, they shed light on the complexities of meat procurement between possibly local production and trade.

A lexical-semantic analysis of anglicisms in sports terminology

Babel ◽  
2019 ◽  
Vol 65 (6) ◽  
pp. 752-768
Author(s):  
Milisav Ilinčić
Keyword(s):  
English Language ◽  
Semantic Analysis ◽  
Daily Basis ◽  
General Classification ◽  
Lexical Semantic ◽  
Complete Answer ◽  
Shed Light ◽  
Linguistic Means

Abstract Anglicisms are words borrowed from the English language that are customarily used in the Serbian language; they are frequently used in the Serbian media and in everyday speech. Trying to shed light on the role and importance of anglicisms in the Serbian language, this paper places a special emphasis on the influence of anglicisms in the sphere of sports terminology. The reasons for conducting an all-encompassing analysis of sports terms are quite obvious. First of all, if we exclude the growing vocabulary pertaining to informatics, we could say that it is precisely in the sphere of sports terminology that the greatest number of anglicisms is to be found. Taking into consideration separate functions of the English language (English for special purposes, English for academic and professional purposes), the paper introduces a general classification of anglicisms, following which, providing numerous examples, it analyses the adaptation of sports terminology within the framework of the Serbian language – on the level of phonology, morphology and semantics. Finally, in order to provide a complete answer to this question, the final research encompasses the broader context of the use of linguistic means. Naturally, the broadening of lexis makes it increasingly diverse and rich on a daily basis, with new syntagms being coined in English, giving surprising results. At this moment, we do not know fully what can be accomplished with them, as their use is still being developed.

scholarly journals Searching for chemical relics of first stars with LAMOST and Subaru

2015 ◽  
Vol 11 (S317) ◽  
pp. 51-56
Author(s):  
Haining Li ◽  
Wako Aoki ◽  
Gang Zhao ◽  
Satoshi Honda ◽  
Norbert Christlieb ◽  
...  
Keyword(s):  
High Resolution ◽  
Galactic Halo ◽  
Heavy Elements ◽  
Red Giants ◽  
Halo Formation ◽  
First Stars ◽  
Joint Project ◽  
Large Sample ◽  
Shed Light

AbstractWe report progresses of a joint project on searching for extremely metal-poor (EMP) stars based on LAMOST survey and Subaru follow-up observation. Follow-up high-resolution snapshot spectra have been obtained for 70 objects, resulting in 42 EMP stars. A number of chemically interesting objects have already been identified, including (1) Two UMP (ultra metal-poor) stars with [Fe/H] ~ −4.0. One of them is the second UMP turnoff star with Li detection. (2) A super Li-rich (A(Li) ~ 3.1) EMP giant. This is the most metal-poor and extreme example of Li enhancement in giants known to date, and will shed light on Li production during the evolution of red giants. (3) A few EMP stars showing extreme overabundance in heavy elements. Detailed abundances of these extreme objects and statistics obtained by the large sample of EMP stars will provide important constraints on the Galactic halo formation.

scholarly journals Radio Emission from Low-Luminosity Active Galactic Nuclei

1998 ◽  
Vol 164 ◽  
pp. 205-206
Author(s):  
Schuyler D. Van Dyk ◽  
Luis C. Ho
Keyword(s):  
High Resolution ◽  
Radio Emission ◽  
Active Galactic Nuclei ◽  
Galactic Nuclei ◽  
Seyfert Galaxies ◽  
Physical Origin ◽  
Common Variety ◽  
Nearby Galaxies ◽  
Optical Evidence ◽  
Shed Light

AbstractMany nearby galaxies show optical evidence for low-luminosity AGNs that are far less luminous than classical Seyfert nuclei and QSOs. LINERs, the most common variety of such emission-line objects, comprise ~ 1/3 of nearby galaxies, and may serve as an important “missing link“ between normal and Seyfert galaxies. To shed light on the physical origin of LINERs, which remains controversial, we are conducting a high-resolution continuum survey of a representative sample of galaxies using the VLA to search for compact radio cores. We additionally discuss the dramatic radio variability in the LINER nucleus of M81.

scholarly journals Molecular Determinants of Selectivity in Disordered Complexes May Shed Light on Specificity in Protein Condensates

Biomolecules ◽  
2022 ◽  
Vol 12 (1) ◽  
pp. 92
Author(s):  
Alexander Miguel Monzon ◽  
Damiano Piovesan ◽  
Monika Fuxreiter
Keyword(s):  
High Resolution ◽  
Selective Recognition ◽  
Conformational Heterogeneity ◽  
Structural Studies ◽  
Sequence Motifs ◽  
Conformational Ensembles ◽  
Wide Range ◽  
Molecular Determinants ◽  
High Degree ◽  
Shed Light

Biomolecular condensates challenge the classical concepts of molecular recognition. The variable composition and heterogeneous conformations of liquid-like protein droplets are bottlenecks for high-resolution structural studies. To obtain atomistic insights into the organization of these assemblies, here we have characterized the conformational ensembles of specific disordered complexes, including those of droplet-driving proteins. First, we found that these specific complexes exhibit a high degree of conformational heterogeneity. Second, we found that residues forming contacts at the interface also sample many conformations. Third, we found that different patterns of contacting residues form the specific interface. In addition, we observed a wide range of sequence motifs mediating disordered interactions, including charged, hydrophobic and polar contacts. These results demonstrate that selective recognition can be realized by variable patterns of weakly defined interaction motifs in many different binding configurations. We propose that these principles also play roles in determining the selectivity of biomolecular condensates.

scholarly journals A plant-like mechanism coupling m6A reading to polyadenylation safeguards transcriptome integrity and developmental genes partitioning in Toxoplasma

2021 ◽  
Author(s):  
Dayana C. Farhat ◽  
Matthew Bowler ◽  
Guillaume Communie ◽  
Dominique Pontier ◽  
Lucid Belmudes ◽  
...  
Keyword(s):  
High Resolution ◽  
Regulatory Mechanism ◽  
List Type ◽  
Regulatory Requirements ◽  
Apicomplexan Parasites ◽  
Transcriptional Termination ◽  
C Terminus ◽  
Cleavage And Polyadenylation ◽  
Host Life ◽  
Shed Light

AbstractCorrect 3’end processing of mRNAs is regarded as one of the regulatory cornerstones of gene expression. In a parasite that must answer to the high regulatory requirements of its multi-host life style, there is a great need to adopt additional means to partition the distinct transcriptional signatures of the closely and tandemly-arranged stage specific genes. In this study, we report on our findings in T. gondii of an m6A-dependent 3’end polyadenylation serving as a transcriptional barrier at these loci. We identify the core polyadenylation complex within T. gondii and establish CPSF4 as a reader for m6A-modified mRNAs, via a YTH domain within its C-terminus, a feature which is shared with plants. We bring evidence of the specificity of this interaction both biochemically, and by determining the crystal structure at high resolution of the T. gondii CPSF4-YTH in complex with an m6A modified RNA. We show that the loss of m6A, both at the level of its deposition or its recognition was associated with an increase in aberrantly elongated chimeric mRNAs emanating from impaired transcriptional termination, a phenotype previously noticed in the plant model Arabidopsis thaliana. We bring Nanopore direct RNA sequencing-based evidence of the occurrence of transcriptional read-through breaching into downstream repressed stage-specific genes, in the absence of either CPSF4 or the m6A RNA methylase components in both T. gondii and A. thaliana. Taken together, our results shed light on an essential regulatory mechanism coupling the pathways of m6A metabolism directly to the cleavage and polyadenylation processes, one that interestingly seem to serve, in both T. gondii and A. thaliana, as a guardian against aberrant transcriptional read-throughs.Highlightsm6A is recognized in apicomplexan and plants by CPSF4, a member of the cleavage and polyadenylation complex machinery.The structural insight behind the specificity of the binding of m6A by the CPSF4 YTH subunit are solved by high resolution crystal structures.The m6A-driven 3’end polyadenylation pathway protects transcriptome integrity by restricting transcriptional read-throughs and RNA chimera formation in apicomplexan parasites and plants.

scholarly journals High-Resolution Infection Kinetics of Entomopathogenic Nematodes Entering Drosophila melanogaster

Insects ◽  
2020 ◽  
Vol 11 (1) ◽  
pp. 60 ◽  
Author(s):  
Alexis Dziedziech ◽  
Sai Shivankar ◽  
Ulrich Theopold
Keyword(s):  
Wound Healing ◽  
High Resolution ◽  
Entomopathogenic Nematodes ◽  
Symbiotic Bacteria ◽  
Spatiotemporal Resolution ◽  
Host Behavior ◽  
Natural Mechanism ◽  
Kinetics Of ◽  
High Resolution Microscopy ◽  
Shed Light

Entomopathogenic nematodes (EPNs) have been a useful model for studying wound healing in insects due to their natural mechanism of entering an insect host either through the cuticle or an orifice. While many experiments have shed light on nematode and host behavior, as well as the host immune response, details regarding early nematode entry and proliferative events have been limited. Using high-resolution microscopy, we provide data on the early infection kinetics of Heterorhabditis bacteriophora and its symbiotic bacteria, Photorhabdus luminescens. EPNs appendage themselves to the host and enter through the host cuticle with a drill-like mechanism while leaving their outer sheath behind. EPNs immediately release their symbiotic bacteria in the host which leads to changes in host behavior and septicemia within 6 h while EPNs travel through the host in a predictable manner, congregating in the anterior end of the host. This paper sheds light on the entry and proliferative events of EPN infection, which will further aid in our understanding of wound healing and host immune activation at a high spatiotemporal resolution.

scholarly journals Explicating verbs for “laughing with other people” in French and English (and why it matters for humour studies)

2020 ◽  
Vol 33 (1) ◽  
pp. 55-77 ◽  
Author(s):  
Cliff Goddard ◽  
Kerry Mullan
Keyword(s):  
Semantic Analysis ◽  
Lexical Semantic ◽  
Cultural Orientations ◽  
Humor Studies ◽  
French And English ◽  
Shed Light

AbstractThis study undertakes a contrastive lexical-semantic analysis of a set of related verbs in English and French (English to joke and to kid, French rigoler and plaisanter), using the Natural Semantic Metalanguage (NSM) approach to semantic analysis. We show that the semantic and conceptual differences between French and English are greater than commonly assumed. These differences, we argue, have significant implications for humor studies: first, they shed light on different cultural orientations towards “laughter talk” in Anglo and French linguacultures; second; they highlight the danger of conceptual Anglocentrism in relying on English-specific words as a theoretical vocabulary for humor studies.

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