Emotional trauma and childhood amnesia

2003 ◽  
Vol 4 (2) ◽  
pp. 151-179
Author(s):  
Rhawn Joseph

It has been reported that, on average, most adults recall first memories formed around age 3.5. In general, most first memories are positive. However, whether these first memories tend to be visual or verbal and whether the period for childhood amnesia (CA) is greater for visual or verbal or for positive versus negative memories has not been determined. Because negative, stressful experiences disrupt memory and can injure memory centers such as the hippocampus and amygdala, and since adults who were traumatized or abused during childhood (TA) reportedly suffer memory disturbances, it was hypothesized that those with a history of early trauma might suffer from a lengthier childhood amnesia and form their first recallable memories at a later age as compared to the general population (GP). Because the right hemisphere matures earlier than the language-dominant left hemisphere, and is dominant for visual and emotional memory, as well as the stress reponse, it was hypothesized that first recallable memories would be visual rather than verbal. Lastly, since stress can injure the brain and disrupt memory, it was hypothesized that the traumatized group would demonstrate memory and intellectual disturbances associated with right hemisphere injury as based on WAIS-R, Wechsler Memory Scale, and facial-memory testing. All hypotheses were supported. Positive and visual memories are formed before negative and verbal memories. TA CA offset, on average, is at age 6.1 versus 3.5 for GPs. TA PIQ (performance IQ), short-term visual memory, and facial memory were significantly reduced.

Author(s):  
Selma Lugtmeijer ◽  
◽  
Linda Geerligs ◽  
Frank Erik de Leeuw ◽  
Edward H. F. de Haan ◽  
...  

AbstractWorking memory and episodic memory are two different processes, although the nature of their interrelationship is debated. As these processes are predominantly studied in isolation, it is unclear whether they crucially rely on different neural substrates. To obtain more insight in this, 81 adults with sub-acute ischemic stroke and 29 elderly controls were assessed on a visual working memory task, followed by a surprise subsequent memory test for the same stimuli. Multivariate, atlas- and track-based lesion-symptom mapping (LSM) analyses were performed to identify anatomical correlates of visual memory. Behavioral results gave moderate evidence for independence between discriminability in working memory and subsequent memory, and strong evidence for a correlation in response bias on the two tasks in stroke patients. LSM analyses suggested there might be independent regions associated with working memory and episodic memory. Lesions in the right arcuate fasciculus were more strongly associated with discriminability in working memory than in subsequent memory, while lesions in the frontal operculum in the right hemisphere were more strongly associated with criterion setting in subsequent memory. These findings support the view that some processes involved in working memory and episodic memory rely on separate mechanisms, while acknowledging that there might also be shared processes.


2012 ◽  
Vol 10 (2) ◽  
pp. 126-129 ◽  
Author(s):  
Kiyoshi Gomi ◽  
Mio Tanaka ◽  
Mariko Yoshida ◽  
Susumu Ito ◽  
Masaki Sonoda ◽  
...  

The authors report on a case of histiocytic sarcoma (HS) in a pediatric patient presenting with a solitary tumor in the cerebellum, with the aim of providing insight into primary HS in the CNS, which is especially rare. A 17-month-old Japanese girl presented with a 2-week history of progressive gait disturbance. Brain MRI revealed a 4.7 × 4.3 × 4.3–cm well-demarcated solitary mass in the right hemisphere of the cerebellum, initially suggestive of medulloblastoma, ependymoma, or anaplastic astrocytoma. On intraoperative inspection the cerebellar tumor showed intensive dural attachment and was subtotally removed. Histological and immunohistochemical findings were consistent with HS. The patient subsequently received chemotherapy, and her preoperative neurological symptoms improved. Primary HS in the CNS usually demonstrates an aggressive clinical course and is currently considered to have a poor prognosis. The possibility of this rare tumor should be included in the differential diagnosis of localized cerebellar tumors in the pediatric age group.


2022 ◽  
Vol 15 ◽  
Author(s):  
Yu Tian ◽  
Jiaming Wang ◽  
Xin Shi ◽  
Zhaohai Feng ◽  
Lei Jiang ◽  
...  

Patients requiring deep brain stimulation due to intracerebral metallic foreign substances have not been reported elsewhere in the world. Additionally, the long-term effects of metallic foreign bodies on deep brain stimulation (DBS) are unknown. A 79-year-old man with a 5-year history of Parkinson's disease (PD) reported that, 40 years ago, while playing with a pistol, a metallic bullet was accidentally discharged into the left brain through the edge of the left eye, causing no discomfort other than blurry vision in the left eye. DBS was performed due to the short duration of efficacy for oral medication. Because the bullet was on the left subthalamic nucleus (STN) electrode trajectory and the patient's right limb was primarily stiff, the patient received globus pallidus interna (GPi)-DBS implantation in the left hemisphere and STN-DBS implantation in the right hemisphere. During a 6-month postoperative follow-up, the patient's PD symptoms were effectively managed with no noticeable discomfort.


2018 ◽  
Vol 20 (2) ◽  
pp. 166-170
Author(s):  
A A Kisina ◽  
E B Filippova

Abstact. Psychophysiological parameters (short-term visual memory, speed of successive addition of numbers in visual perception, indicators in the Raven progressive matrices test and the Stroop test) were investigated among left-handed and right- handed men (aged 19-25 years). It was found that the verbal stimuli perception in competition with the corresponding sensory perception of right-handers are more pronounced. At the same time, sense perception of the image and its indicating verbal stimuli associated to a greater extent for left-handed persons. The advantage of the left-handers in the test of the Raven progressive matrices test and the advantage of the right-handers in the sequential addition of single-valued numbers were noticed. All indicators of short-term visual memory demonstrated the advantage of left-handers. The use of factor analysis showed that right-handers have greater productivity in performing the proposed tests. This is mainly due to the functions of the left hemisphere - verbal thinking and consistent processing of information. The second important factor is visual spatial thinking. Productivity of left-handers is largely determined by the function of the right hemisphere: sensory perception and spatial thinking. The third most important factor is the interaction between figurative and verbal thinking and the attentional set-shifting. Thus, right-handers in a greater extent than left-handed people, have more success in intellectual activity because of the development of the functions of the dominant hemisphere.


2021 ◽  
Vol 36 (6) ◽  
pp. 1093-1094
Author(s):  
Shelby Ming ◽  
John B O'Hara ◽  
Carolina Posada

Abstract Objective Arteriovenous malformations (AVMs) are tangled masses of arteries and veins of congenital origin. AVMs are rare (~4.3% in the general population) and symptomatic cases are rarer still (0.1–1%). AVMs account for strokes in 1–2% of cases. We present the case of a 59-year-old, right-handed, Caucasian male, with nine years of formal education, who was evaluated as an inpatient following a ruptured AVM. Method Patient with known history of AVM (Figure 1) presented with headache and new onset seizure. Computerized tomography (CT) revealed rupture of an AVM at the right temporal-occipital junction, with resulting intraparenchymal hemorrhage within the right parieto-occipital lobe and the right ventricular system and 0.8 cm left midline shift (Figure 2). The patient underwent emergency craniotomy for evacuation of intracerebral hematoma, resection of AVM, and placement of right external ventricular drain (EVD). Electroencephalograom (EEG) revealed focal cortical dysfunction over the right hemisphere and moderate encephalopathy. Results (Table 1). Neuropsychological evaluation six days following emergency craniotomy revealed primary impairment in visuoperceptual and visuoconstructional skills (including left neglect; Figures 3 & 4), impairments in working memory, learning/memory of verbal information (with intact recognition), as well as impairment in aspects of language (semantic fluency). These were accompanied by dense anosagnosia pertaining to cognitive deficits, but intact insight related to his hospitalization. Conclusions This is a rare case of symptomatic AVM with neuropsychological evaluation data highlighting the associated evolving cognitive (e.g., left neglect and visuoperceptual disturbance) and neuropsychiatric deficits (e.g., dense anosagnosia) in the context of recent neurosurgical interventions (e.g., evacuation of hemorrhage, placement of EVD, etc.).


Author(s):  
Andrew Kirk ◽  
L.C. Ang

Abstract:A 64-year-old man presented with a three day history of progressive Broca’s aphasia, followed within 3 weeks by exclusively right-sided myoclonus, rigidity, and dystonia. Within 4 weeks he was globally aphasie. He died within 7 weeks of onset. In the final week, rigidity and myoclonus became bilateral. CT and MRI were normal. SPECT showed diminished perfusion of the left hemisphere. EEG showed periodic discharges on the left. At autopsy, there were marked cortical spongiform change, neuronal loss, and gliosis throughout the left hemisphere and in the right occipital cortex. Elsewhere in the right hemisphere, spongiform change was non-existent to minimal. There was moderate spongiform change in the molecular layer of the cerebellar cortex, much more marked on the left. Clinical and pathological unilateral cerebral predominance extended to the ipsilateral cerebellum. Creutzfeldt-Jakob disease is an important consideration in patients with rapidly progressive unilateral cerebral signs associated with a movement disorder.


2021 ◽  
Vol 11 (12) ◽  
pp. 1584
Author(s):  
Yann Cojan ◽  
Arnaud Saj ◽  
Patrik Vuilleumier

Several cortical and sub-cortical regions in the right hemisphere, particularly in the parietal and frontal lobes, but also in the temporal lobe and thalamus, are part of neural networks critically implicated in spatial and attentional functions. Damage to different sites within these networks can cause hemispatial neglect. The aim of this study was to identify the neural substrates of different spatial processing components that are known to contribute to neglect symptoms. Firstly, three different spatial tasks (visual search, bisection, and visual memory) were tested in 26 healthy controls. The fMRI results showed a differential activation of regions in the parietal and frontal lobes during bisection and visual search, respectively. Secondly, fMRI was used in 27 patients with focal right brain damage. Voxel-based lesion–symptom mapping was used to determine the relationships between specific sites of damage and the severity of deficits in these three spatial tasks. In the patients, we confirmed a critical role of the right lateral parietal cortex in bisection, but lesions in the frontal and temporal lobes were critical for visual search. These data support the existence of distinct components in spatial attentional processes that might be damaged to different degrees in neglect patients.


2021 ◽  
Author(s):  
Matías Baldoncini ◽  
Alvaro Campero ◽  
Sabino Luzzi ◽  
Juan F Villalonga

Abstract Neurovascular procedures along the interhemispheric fissure harbor unique features differentiating them from those arteriovenous malformations (AVMs) located at the lateral surface of the brain.1-4  The aim of this 3-dimensional operative video is to present a microsurgical resection of an AVM in a subparacentral location, operated through an interhemispheric contralateral transfalcine approach.1,3,5  This is a case of a 29-yr-old female, with headaches and history of seizures. The patient presented an interhemispheric bleeding 6 mo before the surgery. The magnetic resonance imaging (MRI) showed a vascular lesion located on the medial surface of the right hemisphere at the confluence between the cingulate sulcus and its ascending sulcus. In the cerebral angiography, a right medial AVM was observed, receiving afference from the right anterior cerebral artery and draining to the superior longitudinal sinus. The patient signed an informed consent for the procedure and agreed with the use of her images and surgical video for research and academic purposes.  The patient was in a supine position, and a left interhemispheric contralateral transfalcine approach was performed,1-3 a circumferential dissection of the nidus, and, finally, the AVM was resected in one piece.  The patient evolved without neurological deficits after the surgery. The postoperative MRI and angiography showed a complete resection of the AVM.  In the case presented, to avoid exposing the drainage vein first and to use the gravity of the exposure, the contralateral transfalcine interhemispheric approach was used,1,2 which finally accomplished the proposed objectives.


2017 ◽  
Vol 9 (1) ◽  
pp. 98-105 ◽  
Author(s):  
Charlotte Lützhøft Rath ◽  
Jun He ◽  
Mette Maria Nordling ◽  
Troels Wienecke

Stroke mimics, like attacks of hemiplegic migraine, are challenging in acute stroke evaluation. We present a 28-year-old woman with a suspected hemiplegic migraine attack with left-sided hemiparalysis. Brain CT with perfusion imaging 1 h 54 min after symptom onset revealed hypoperfusion in the right hemisphere. The patient was treated with intravenous recombinant tissue plasminogen activator (rtPA) with no effect. After a subsequent intravenous verapamil infusion, the patient gained full motor function within 10 min. Brain magnetic resonance imaging (MRI) performed 5 h 46 min after symptom onset revealed diffusion restriction in the same area as the hypoperfusion on CT. There were no notable changes on T2 images. The patient stayed clinically in remission, except for reduced sensation for all modalities on the extremities on the left side. Although brain CT 24 h after symptom onset revealed an edema in the same area, an MRI performed 17 days later showed no new infarctions. Young patients with a history of migraine with aura admitted with symptoms of acute ischemic stroke are at risk of insufficient treatment. Calcium antagonists might be considered if there is no effect of first-line treatment with rtPA.


2008 ◽  
Vol 14 (5) ◽  
pp. 902-911 ◽  
Author(s):  
MARINA GASPARINI ◽  
ANNE MARIE HUFTY ◽  
GIOVANNI MASCIARELLI ◽  
DONATELLA OTTAVIANI ◽  
UGO ANGELONI ◽  
...  

Visual Imagery is the ability to generate mental images in the absence of perception, that is, “seeing with the mind's eye.” We describe a patient, IM, who suffered from an acute ischemic stroke in the right anterior choroidal artery who appeared to demonstrate relatively isolated impairment in visual imagery. Her cognitive function, including her performance on tests of semantic function, was at ceiling, apart from a deficit in visual memory. IM failed in tasks involving degraded stimuli, object decision involving reality judgments on normal animals, and drawings from memory. By contrast, she was able to match objects seen from an unfamiliar viewpoint and to perform tasks of semantic and visual association. We hypothesize that IM has a visual working memory deficit that impairs her ability to generate full visual representations of objects given their names, individual feature, or partial representations. The deficit appears to be the result of damage to connections between the right thalamus and the right temporal lobe. Our findings may help to clarify the role of the thalamus in the cortical selective engagement processes that underlie working memory. (JINS, 2008, 14, 902–911.)


Sign in / Sign up

Export Citation Format

Share Document