Computer-aided translation as a distributed cognitive task

Author(s):  
Barbara Dragsted
1986 ◽  
Vol 30 (5) ◽  
pp. 492-496 ◽  
Author(s):  
R. Koubek ◽  
G. Salvendy ◽  
H. Dunsmore

A current bottleneck In the automation of software Is the lack of available, standardized, reliable and valid methods for extracting knowledge from expert programmers. This paper discusses the development of Computer Aided Protocol (CAP) to automatically collect the general and specific cognitive task components of a programmer. Results Indicate that CAP was able to collect lower level goals while protocol analysis collected only 56 percent of these lower level goals. However, protocol analysis was able to obtain significantly more procedural knowledge relating to cognitive states of the subject and more high level goals than CAP (F(1,8)=11.23; p<.004). This work suggests that the integration of the information derived from both protocol and CAP for knowledge extraction would provide more effective information for the development of expert systems than is feasible with either system alone.


Author(s):  
Mark Ellisman ◽  
Maryann Martone ◽  
Gabriel Soto ◽  
Eleizer Masliah ◽  
David Hessler ◽  
...  

Structurally-oriented biologists examine cells, tissues, organelles and macromolecules in order to gain insight into cellular and molecular physiology by relating structure to function. The understanding of these structures can be greatly enhanced by the use of techniques for the visualization and quantitative analysis of three-dimensional structure. Three projects from current research activities will be presented in order to illustrate both the present capabilities of computer aided techniques as well as their limitations and future possibilities.The first project concerns the three-dimensional reconstruction of the neuritic plaques found in the brains of patients with Alzheimer's disease. We have developed a software package “Synu” for investigation of 3D data sets which has been used in conjunction with laser confocal light microscopy to study the structure of the neuritic plaque. Tissue sections of autopsy samples from patients with Alzheimer's disease were double-labeled for tau, a cytoskeletal marker for abnormal neurites, and synaptophysin, a marker of presynaptic terminals.


Author(s):  
Greg V. Martin ◽  
Ann L. Hubbard

The microtubule (MT) cytoskeleton is necessary for many of the polarized functions of hepatocytes. Among the functions dependent on the MT-based cytoskeleton are polarized secretion of proteins, delivery of endocytosed material to lysosomes, and transcytosis of integral plasma membrane (PM) proteins. Although microtubules have been shown to be crucial to the establishment and maintenance of functional and structural polarization in the hepatocyte, little is known about the architecture of the hepatocyte MT cytoskeleton in vivo, particularly with regard to its relationship to PM domains and membranous organelles. Using an in situ extraction technique that preserves both microtubules and cellular membranes, we have developed a protocol for immunofluorescent co-localization of cytoskeletal elements and integral membrane proteins within 20 µm cryosections of fixed rat liver. Computer-aided 3D reconstruction of multi-spectral confocal microscope images was used to visualize the spatial relationships among the MT cytoskeleton, PM domains and intracellular organelles.


2001 ◽  
Vol 6 (1) ◽  
pp. 15-25 ◽  
Author(s):  
Harald Walach ◽  
Stefan Schmidt ◽  
Yvonne-Michelle Bihr ◽  
Susanne Wiesch

We studied the effect of experimenter expectations and different instructions in a balanced placebo design. 157 subjects were randomized into a 2 × 4 factorial design. Two experimenters were led to expect placebos either to produce physiological effects or not (pro- vs. antiplacebo). All subjects except a control group received a caffeine placebo. They were either made to expect coffee, no coffee, or were in a double-blind condition. Dependent measures were blood pressure, heart rate, well-being, and a cognitive task. There was one main effect on the instruction factor (p = 0.03) with the group “told no caffeine” reporting significantly better well-being. There was one main effect on the experimenter factor with subjects instructed by experimenter “proplacebo” having higher systolic blood pressure (p = 0.008). There was one interaction with subjects instructed by experimenter “proplacebo” to receive coffee doing worse in the cognitive task than the rest. Subjects instructed by experimenter “antiplacebo” were significantly less likely to believe the experimental instruction, and that mostly if they had been instructed to receive coffee. Contrary to the literature we could not show an effect of instruction, but there was an effect of experimenters. It is likely, however, that these experimenter effects were not due to experimental manipulations, but to the difference in personalities.


2019 ◽  
Vol 35 (6) ◽  
pp. 878-890 ◽  
Author(s):  
David Marcusson-Clavertz ◽  
Oscar N. E. Kjell

Abstract. Thinking about task-unrelated matters (mind wandering) is related to cognition and well-being. However, the relations between mind wandering and other psychological variables may depend on whether the former commence spontaneously or deliberately. The current two studies investigated the psychometric properties of the Spontaneous and Deliberate Mind Wandering Scales (SDMWS; Carriere, Seli, & Smilek, 2013 ). Study 1 evaluated the stability of the scales over 2 weeks ( N = 284 at Time 1), whereas Study 2 ( N = 323) evaluated their relations to Generalized anxiety disorder symptoms, Openness, Social desirability, and experience-sampling reports of intentional and unintentional mind wandering during an online cognitive task. The results indicated that the SDMWS were better fitted with a two-factor than a one-factor solution, although the fit was improved with the exclusion of one item. The scales exhibited strong measurement invariance across gender and time, and moderately high test-retest reliability. Spontaneous mind wandering predicted Generalized anxiety disorder and experience-sampling reports of unintentional mind wandering, whereas Deliberate mind wandering predicted Openness and experience-sampling reports of intentional mind wandering. Furthermore, Spontaneous mind wandering showed a negative association with social desirability of weak-to-medium strength. In sum, the scales generally showed favorable psychometric properties.


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