Ligand-specific Conformational Changes in the α1 Glycine Receptor Ligand-binding Domain

Stephan A. Pless; Joseph W. Lynch

doi:10.1074/jbc.m809343200

Ligand-specific Conformational Changes in the α1 Glycine Receptor Ligand-binding Domain

Journal of Biological Chemistry ◽

10.1074/jbc.m809343200 ◽

2009 ◽

Vol 284 (23) ◽

pp. 15847-15856 ◽

Cited By ~ 47

Author(s):

Stephan A. Pless ◽

Joseph W. Lynch

Keyword(s):

Ligand Binding ◽

Conformational Changes ◽

Glycine Receptor ◽

Binding Domain ◽

Ligand Binding Domain ◽

Receptor Ligand

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A comparison of glycine- and ivermectin-mediated conformational changes in the glycine receptor ligand-binding domain

The International Journal of Biochemistry & Cell Biology ◽

10.1016/j.biocel.2011.11.005 ◽

2012 ◽

Vol 44 (2) ◽

pp. 335-340 ◽

Cited By ~ 9

Author(s):

Qian Wang ◽

Joseph W. Lynch

Keyword(s):

Ligand Binding ◽

Conformational Changes ◽

Glycine Receptor ◽

Binding Domain ◽

Ligand Binding Domain ◽

Receptor Ligand

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The Free Energy Landscapes Governing Conformational Changes in a Glutamate Receptor Ligand-Binding Domain

Structure ◽

10.1016/j.str.2007.07.015 ◽

2007 ◽

Vol 15 (10) ◽

pp. 1203-1214 ◽

Cited By ~ 77

Author(s):

Albert Y. Lau ◽

Benoît Roux

Keyword(s):

Free Energy ◽

Ligand Binding ◽

Glutamate Receptor ◽

Conformational Changes ◽

Binding Domain ◽

Ligand Binding Domain ◽

Energy Landscapes ◽

Receptor Ligand ◽

Free Energy Landscapes

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Homology modeling and molecular dynamics simulations of the glycine receptor ligand binding domain

Proteins Structure Function and Bioinformatics ◽

10.1002/prot.21251 ◽

2007 ◽

Vol 67 (4) ◽

pp. 950-960 ◽

Cited By ~ 19

Author(s):

Kirill Speranskiy ◽

Michael Cascio ◽

Maria Kurnikova

Keyword(s):

Molecular Dynamics ◽

Ligand Binding ◽

Homology Modeling ◽

Molecular Dynamics Simulations ◽

Glycine Receptor ◽

Binding Domain ◽

Ligand Binding Domain ◽

Receptor Ligand ◽

Dynamics Simulations

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Three-dimensional structure of homodimeric androgen receptor ligand-binding domain

Endocrine Abstracts ◽

10.1530/endoabs.42.il3 ◽

2016 ◽

Author(s):

Eva Estebanez Perpina

Keyword(s):

Androgen Receptor ◽

Ligand Binding ◽

Three Dimensional ◽

Binding Domain ◽

Ligand Binding Domain ◽

Dimensional Structure ◽

Receptor Ligand ◽

Three Dimensional Structure

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Human formyl peptide receptor ligand binding domain(s). Studies using an improved mutagenesis/expression vector reveal a novel mechanism for the regulation of receptor occupancy.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(17)31671-x ◽

1994 ◽

Vol 269 (36) ◽

pp. 22485-22487

Author(s):

H.D. Perez ◽

L. Vilander ◽

W.H. Andrews ◽

R. Holmes

Keyword(s):

Ligand Binding ◽

Expression Vector ◽

Receptor Occupancy ◽

Binding Domain ◽

Ligand Binding Domain ◽

Formyl Peptide Receptor ◽

Receptor Ligand ◽

Peptide Receptor ◽

Formyl Peptide

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Mechanism of Vitamin D Receptor Ligand-Binding Domain Regulation Studied by gREST Simulations

Journal of Chemical Information and Modeling ◽

10.1021/acs.jcim.1c00534 ◽

2021 ◽

Author(s):

Toru Ekimoto ◽

Takafumi Kudo ◽

Tsutomu Yamane ◽

Mitsunori Ikeguchi

Keyword(s):

Vitamin D ◽

Ligand Binding ◽

Vitamin D Receptor ◽

Binding Domain ◽

Ligand Binding Domain ◽

Receptor Ligand

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Application of Oestrogen Receptor Ligand Binding Domain to the Generic Isolation of Oestrogens by Receptor Affinity Chromatography

Chromatographia ◽

10.1365/s10337-003-0246-4 ◽

2004 ◽

Vol 59 (S1) ◽

pp. S123-S130 ◽

Cited By ~ 1

Author(s):

M. F. Byford ◽

M. J. Sauer

Keyword(s):

Ligand Binding ◽

Affinity Chromatography ◽

Oestrogen Receptor ◽

Binding Domain ◽

Ligand Binding Domain ◽

Receptor Ligand ◽

Receptor Affinity

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Simulations of the Estrogen Receptor Ligand-Binding Domain: Affinity of Natural Ligands and Xenoestrogens

Journal of Medicinal Chemistry ◽

10.1021/jm001045d ◽

2000 ◽

Vol 43 (24) ◽

pp. 4594-4605 ◽

Cited By ~ 72

Author(s):

B. Chris Oostenbrink ◽

Jed W. Pitera ◽

Marola M. H. van Lipzig ◽

John H. N. Meerman ◽

Wilfred F. van Gunsteren

Keyword(s):

Estrogen Receptor ◽

Ligand Binding ◽

Binding Domain ◽

Ligand Binding Domain ◽

Receptor Ligand ◽

Natural Ligands ◽

Estrogen Receptor Ligand

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Dynamic and Strucutral Effects of Ligand and Coregulator Binding on Estrogen Receptor Ligand Binding Domain Measured by Electron Paramagnetic Resonance

Biophysical Journal ◽

10.1016/j.bpj.2008.12.2966 ◽

2009 ◽

Vol 96 (3) ◽

pp. 548a

Author(s):

Stefano V. Gulla

Keyword(s):

Electron Paramagnetic Resonance ◽

Estrogen Receptor ◽

Ligand Binding ◽

Binding Domain ◽

Ligand Binding Domain ◽

Paramagnetic Resonance ◽

Receptor Ligand ◽

Estrogen Receptor Ligand ◽

Electron Paramagnetic

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Comparative analysis of interactions between aryl hydrocarbon receptor ligand binding domain with its ligands: a computational study

BMC Structural Biology ◽

10.1186/s12900-018-0095-2 ◽

2018 ◽

Vol 18 (1) ◽

Cited By ~ 6

Author(s):

Kumaraswamy Naidu Chitrala ◽

Xiaoming Yang ◽

Prakash Nagarkatti ◽

Mitzi Nagarkatti

Keyword(s):

Comparative Analysis ◽

Ligand Binding ◽

Aryl Hydrocarbon Receptor ◽

Computational Study ◽

Binding Domain ◽

Ligand Binding Domain ◽

Receptor Ligand ◽

Aryl Hydrocarbon Receptor Ligand ◽

Aryl Hydrocarbon

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