Mitochondrial Hexokinase II Promotes Neuronal Survival and Acts Downstream of Glycogen Synthase Kinase-3

Alfredo Gimenez-Cassina; Filip Lim; Toñi Cerrato; Gloria M. Palomo; Javier Diaz-Nido

doi:10.1074/jbc.m808698200

Mitochondrial Hexokinase II Promotes Neuronal Survival and Acts Downstream of Glycogen Synthase Kinase-3

Journal of Biological Chemistry ◽

10.1074/jbc.m808698200 ◽

2008 ◽

Vol 284 (5) ◽

pp. 3001-3011 ◽

Cited By ~ 43

Author(s):

Alfredo Gimenez-Cassina ◽

Filip Lim ◽

Toñi Cerrato ◽

Gloria M. Palomo ◽

Javier Diaz-Nido

Keyword(s):

Glycogen Synthase ◽

Neuronal Survival ◽

Glycogen Synthase Kinase ◽

Glycogen Synthase Kinase 3 ◽

Hexokinase Ii

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Regulation and Function of Glycogen Synthase Kinase-3 Isoforms in Neuronal Survival

Journal of Biological Chemistry ◽

10.1074/jbc.m605178200 ◽

2007 ◽

Vol 282 (6) ◽

pp. 3904-3917 ◽

Cited By ~ 91

Author(s):

Min-Huei Liang ◽

De-Maw Chuang

Keyword(s):

Glycogen Synthase ◽

Neuronal Survival ◽

Glycogen Synthase Kinase ◽

Glycogen Synthase Kinase 3 ◽

And Function

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Glycogen synthase kinase-3 alpha

Targeted Protein Database ◽

10.2970/tpdb.2008.169 ◽

2008 ◽

Author(s):

Richard Jope

Keyword(s):

Glycogen Synthase ◽

Glycogen Synthase Kinase ◽

Glycogen Synthase Kinase 3

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Faculty Opinions recommendation of A role for glycogen synthase kinase-3 in mitotic spindle dynamics and chromosome alignment.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1009885.183176 ◽

2003 ◽

Author(s):

Inke Nathke

Keyword(s):

Mitotic Spindle ◽

Glycogen Synthase ◽

Glycogen Synthase Kinase ◽

Glycogen Synthase Kinase 3 ◽

Spindle Dynamics ◽

Chromosome Alignment

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Faculty Opinions recommendation of Unrestrained glycogen synthase kinase-3 beta activity leads to activated T cell death and can be inhibited by natural adjuvant.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1088692.542807 ◽

2007 ◽

Author(s):

E Charles Snow

Keyword(s):

Cell Death ◽

T Cell ◽

Glycogen Synthase ◽

Glycogen Synthase Kinase ◽

Glycogen Synthase Kinase 3 ◽

Beta Activity ◽

Activated T Cell

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Faculty Opinions recommendation of Glycogen synthase kinase 3 in MLL leukaemia maintenance and targeted therapy.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1124909.602412 ◽

2009 ◽

Author(s):

Ron Prywes ◽

Susanne Muehlich

Keyword(s):

Targeted Therapy ◽

Glycogen Synthase ◽

Glycogen Synthase Kinase ◽

Glycogen Synthase Kinase 3

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Faculty Opinions recommendation of Erythropoietin affords additional cardioprotection to preconditioned hearts by enhanced phosphorylation of glycogen synthase kinase-3 beta.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.12581.470066 ◽

2006 ◽

Author(s):

Yukio Hayashi

Keyword(s):

Glycogen Synthase ◽

Glycogen Synthase Kinase ◽

Glycogen Synthase Kinase 3

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Faculty Opinions recommendation of Glycogen synthase kinase-3 is an in vivo regulator of hematopoietic stem cell repopulation.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.9082.466571 ◽

2006 ◽

Author(s):

Dan Kaufman

Keyword(s):

Stem Cell ◽

Hematopoietic Stem Cell ◽

Glycogen Synthase ◽

Glycogen Synthase Kinase ◽

Glycogen Synthase Kinase 3 ◽

Hematopoietic Stem ◽

Cell Repopulation

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N-(4-bromophenethyl) Caffeamide Inhibits Melanogenesis by Regulating AKT/Glycogen Synthase Kinase 3 Beta/Microphthalmia-associated Transcription Factor and Tyrosinase-related Protein 1/Tyrosinase

Current Pharmaceutical Biotechnology ◽

10.2174/1389201016666150817094258 ◽

2015 ◽

Vol 16 (12) ◽

pp. 1111-1119 ◽

Cited By ~ 10

Author(s):

Yueh-Hsiung Kuo ◽

Chien-Chia Chen ◽

Ping Lin ◽

Ya-Jhen You ◽

Hsiu-Mei Chiang

Keyword(s):

Transcription Factor ◽

Glycogen Synthase ◽

Glycogen Synthase Kinase ◽

Glycogen Synthase Kinase 3 ◽

Related Protein ◽

Tyrosinase Related Protein

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Multiple Roles for Glycogen Synthase Kinase-3 as a Drug Target in Alzheimers Disease

Current Drug Targets ◽

10.2174/1389450110607011389 ◽

2006 ◽

Vol 7 (11) ◽

pp. 1389-1397 ◽

Cited By ~ 54

Author(s):

Hui-Chuan Huang ◽

Peter Klein

Keyword(s):

Drug Target ◽

Glycogen Synthase ◽

Multiple Roles ◽

Glycogen Synthase Kinase ◽

Glycogen Synthase Kinase 3 ◽

Alzheimers Disease

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QSAR Studies for the Pharmacological Inhibition of Glycogen Synthase Kinase-3

Medicinal Chemistry ◽

10.2174/157340607781024375 ◽

2007 ◽

Vol 3 (4) ◽

pp. 393-417 ◽

Cited By ~ 5

Author(s):

Pablo R. Duchowicz ◽

Eduardo A. Castro

Keyword(s):

Glycogen Synthase ◽

Glycogen Synthase Kinase ◽

Glycogen Synthase Kinase 3 ◽

Qsar Studies ◽

Pharmacological Inhibition

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