scholarly journals The Association of GSK3β with E2F1 Facilitates Nerve Growth Factor-induced Neural Cell Differentiation

2008 ◽  
Vol 283 (21) ◽  
pp. 14506-14515 ◽  
Author(s):  
Fangfang Zhou ◽  
Long Zhang ◽  
Aijun Wang ◽  
Bo Song ◽  
Kai Gong ◽  
...  
Keyword(s):  
Cell Differentiation ◽  
Nerve Growth Factor ◽  
Growth Factor ◽  
Neural Cell ◽  
Nerve Growth

Effect of monoclonal antibodies to bovine nerve growth factor (NGF) on NGF-induced cell differentiation in vitro

1989 ◽  
Vol 108 (5) ◽  
pp. 1648-1650
Author(s):  
E. S. Kakpakova ◽  
E. M. Malakhova ◽  
S. N. Gnedoi ◽  
T. V. Pochechueva ◽  
I. A. Filatov ◽  
...  
Keyword(s):  
Monoclonal Antibodies ◽  
Cell Differentiation ◽  
Nerve Growth Factor ◽  
Growth Factor ◽  
Nerve Growth

scholarly journals Synergistic effects of nerve growth factor and granulocyte-macrophage colony-stimulating factor on human basophilic cell differentiation

Blood ◽  
1991 ◽  
Vol 77 (5) ◽  
pp. 971-979 ◽  
Author(s):  
T Tsuda ◽  
D Wong ◽  
J Dolovich ◽  
J Bienenstock ◽  
J Marshall ◽  
...  
Keyword(s):  
Cell Differentiation ◽  
Nerve Growth Factor ◽  
Growth Factor ◽  
Colony Stimulating Factor ◽  
Nerve Growth ◽  
Basophilic Cell ◽  
Gm Csf ◽  
Macrophage Colony Stimulating Factor ◽  
Macrophage Colony ◽  
Stimulating Factor

Abstract We have recently shown that nerve growth factor (NGF) promotes human granulopoiesis, specifically augmenting basophilic cell differentiation observed in methylcellulose hematopoietic colony assays of human peripheral blood. Because the NGF effect was seen in the presence of conditioned medium derived from a human T-cell line (Mo-CM) containing granulocyte-macrophage colony-stimulating factor (GM-CSF), we examined interactions of purified NGF and recombinant human GM-CSF (rhGM-CSF) on granulocyte growth and differentiation. rhGM-CSF stimulated a dose- dependent increase in methylcellulose colony growth at concentrations between 0.1 U/mL and 10 U/mL, and in the presence of NGF at 500 ng/mL this effect was enhanced. The number of basophilic cell colony-forming units (CFU-Baso) and histamine-positive colonies increased synergistically when NGF was added to rhGM-CSF. Furthermore, because Mo- CM acts with sodium butyrate to promote basophilic differentiation of alkaline-passaged myeloid leukemia cells, HL-60, we also examined the interaction of NGF and Mo-CM or rhGM-CSF using this assay. In the presence of NGF, Mo-CM at concentrations of 0.5% to 20% vol/vol, and rhGM-CSF at concentrations of 0.1 U/mL to 100 U/mL synergistically increased histamine production by butyrate-induced, alkaline-passaged HL-60 cells; this was associated with the appearance of metachromatic, tryptase-negative, IgE receptor-positive cells. The effects of rhGM-CSF or Mo-CM were completely abrogated by a specific anti-rhGM-CSF neutralizing antibody in methylcellulose, with or without NGF; the NGF synergy with rhGM-CSF in the HL-60 assay was also inhibited by either anti-rhGM-CSF or anti-NGF antibody. These studies support the notion that differentiation in the basophilic lineage may be enhanced by NGF acting to increase the number of GM-CSF-responsive basophilic cell progenitors.

scholarly journals Magnaporthe Rab5 homologs show distinct functions in nerve growth factor (NGF)-mediated neurite outgrowth and cell differentiation

2015 ◽  
Vol 14 (5) ◽  
pp. 823-829
Author(s):  
Yao-yao QI ◽  
Zhi-min LIANG ◽  
Jie ZHOU ◽  
Zong-hua WANG ◽  
Guo-dong LU ◽  
...  
Keyword(s):  
Cell Differentiation ◽  
Nerve Growth Factor ◽  
Growth Factor ◽  
Neurite Outgrowth ◽  
Nerve Growth

Role of nerve growth factor in the regulation of parotid cell differentiation induced by rat serum

2003 ◽  
Vol 65 (9) ◽  
pp. 1507-1513 ◽  
Author(s):  
Takashi Takeuchi ◽  
John M Aletta ◽  
Suzanne G Laychock ◽  
Yingrao Tian ◽  
Ronald P Rubin
Keyword(s):  
Cell Differentiation ◽  
Nerve Growth Factor ◽  
Growth Factor ◽  
Rat Serum ◽  
Nerve Growth

scholarly journals The Mixture of Gotu Kola, Cnidium Fruit, and Goji Berry Enhances Memory Functions by Inducing Nerve-Growth-Factor-Mediated Actions Both In Vitro and In Vivo

Nutrients ◽  
2020 ◽  
Vol 12 (5) ◽  
pp. 1372
Author(s):  
Jin Gyu Choi ◽  
Zahra Khan ◽  
Seong Min Hong ◽  
Young Choong Kim ◽  
Myung Sook Oh ◽  
...  
Keyword(s):  
Cell Differentiation ◽  
Nerve Growth Factor ◽  
Growth Factor ◽  
Neuronal Cell ◽  
Main Role ◽  
Memory Functions ◽  
Nerve Growth ◽  
Goji Berry

Nerve growth factor (NGF), a typical neurotrophin, has been characterized by the regulation of neuronal cell differentiation and survival involved in learning and memory functions. NGF has a main role in neurite extension and synapse formation by activating the cyclic adenosine monophosphate-response-element-binding protein (CREB) in the hippocampus. The purpose of this study was to determine whether a mixture of Gotu Kola, Cnidium fruit, and Goji berry (KYJ) enhances memory function by inducing NGF-mediated actions both in vitro and in vivo. The KYJ combination increased NGF concentration and neurite length in C6 glioma and N2a neuronal cells, respectively. Additionally, we discovered memory-enhancing effects of KYJ through increased NGF-mediated synapse maturation, CREB phosphorylation, and cell differentiation in the mouse hippocampus. These findings suggest that this combination may be a potential nootropic cognitive enhancer via the induction of NGF and NGF-dependent activities.

Human Basophilic Cell Differentiation Promoted by 2.5S Nerve Growth Factor

1988 ◽  
Vol 86 (4) ◽  
pp. 453-457 ◽  
Author(s):  
Hiroshi Matsuda ◽  
Jan Switzer ◽  
Michael D. Coughlin ◽  
John Bienenstock ◽  
Judah A. Denburg
Keyword(s):  
Cell Differentiation ◽  
Nerve Growth Factor ◽  
Growth Factor ◽  
Nerve Growth ◽  
Basophilic Cell

Enhancement of neural cell lines proliferation using nano-structured chitosan/poly(vinyl alcohol) scaffolds conjugated with nerve growth factor

2011 ◽  
Vol 86 (2) ◽  
pp. 526-535 ◽  
Author(s):  
Fatemeh Mottaghitalab ◽  
Mehdi Farokhi ◽  
Vahid Mottaghitalab ◽  
Mohammad Ziabari ◽  
Adeleh Divsalar ◽  
...  
Keyword(s):  
Nerve Growth Factor ◽  
Growth Factor ◽  
Cell Lines ◽  
Vinyl Alcohol ◽  
Neural Cell ◽  
Poly Vinyl Alcohol ◽  
Nerve Growth ◽  
Neural Cell Lines
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