scholarly journals Structural and Functional Characterization of a Novel T Cell Receptor Co-regulatory Protein Complex, CD97-CD55

2007 ◽  
Vol 282 (30) ◽  
pp. 22023-22032 ◽  
Author(s):  
Rachel J. M. Abbott ◽  
Ian Spendlove ◽  
Pietro Roversi ◽  
Hannah Fitzgibbon ◽  
Vroni Knott ◽  
...  
Keyword(s):  
T Cell ◽  
T Cell Receptor ◽  
Protein Complex ◽  
Functional Characterization ◽  
Regulatory Protein ◽  
Cell Receptor

scholarly journals Functional characterization of a T-cell receptor BV6+T-cell clone derived from a leprosy lesion

Immunology ◽  
2007 ◽  
Vol 120 (3) ◽  
pp. 354-361 ◽  
Author(s):  
Shereen Sabet ◽  
Maria-Teresa Ochoa ◽  
Peter A. Sieling ◽  
Thomas H. Rea ◽  
Robert L. Modlin
Keyword(s):  
T Cell ◽  
T Cell Receptor ◽  
Cell Clone ◽  
Functional Characterization ◽  
Cell Receptor ◽  
T Cell Clone

Functional Characterization of T-cell Clones Using Related T-Cell Receptor V Gene Segments

1989 ◽  
pp. 550-551
Author(s):  
Edward J. Ball ◽  
Kay Black ◽  
Marie Hoover ◽  
J. Donald Capra ◽  
Peter Stastny
Keyword(s):  
T Cell ◽  
T Cell Receptor ◽  
Functional Characterization ◽  
Cell Receptor ◽  
T Cell Clones ◽  
Cell Clones ◽  
V Gene

Morphologic and functional characterization of human peripheral blood T cells expressing the T cell receptor γ/δ*

1989 ◽  
Vol 19 (7) ◽  
pp. 1183-1188 ◽  
Author(s):  
Silvano Ferrini ◽  
Daniela Zarcone ◽  
Maurizio Viale ◽  
Giannamaria Cerruti ◽  
Romano Millo ◽  
...  
Keyword(s):  
T Cells ◽  
T Cell ◽  
T Cell Receptor ◽  
Peripheral Blood ◽  
Human Peripheral Blood ◽  
Functional Characterization ◽  
Cell Receptor

scholarly journals Characterization of human T cells reactive with the Mycoplasma arthritidis-derived superantigen (MAM): generation of a monoclonal antibody against V beta 17, the T cell receptor gene product expressed by a large fraction of MAM-reactive human T cells.

1991 ◽  
Vol 174 (4) ◽  
pp. 891-900 ◽  
Author(s):  
S M Friedman ◽  
M K Crow ◽  
J R Tumang ◽  
M Tumang ◽  
Y Q Xu ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
T Cells ◽  
T Cell ◽  
T Cell Receptor ◽  
Cell Activity ◽  
Cell Receptor ◽  
Cytotoxic T Cell ◽  
Mycoplasma Arthritidis ◽  
Human T Cells

While all known microbial superantigens are mitogenic for human peripheral blood lymphocytes (PBL), the functional response induced by Mycoplasma arthritidis-derived superantigen (MAM) is unique in that MAM stimulation of PBL consistently results in T cell-dependent B cell activation characterized by polyclonal IgM and IgG production. These immunostimulatory effects of MAM on the humoral arm of the human immune system warranted a more precise characterization of MAM-reactive human T cells. Using an uncloned MAM reactive human T cell line as immunogen, we have generated a monoclonal antibody (mAb) (termed C1) specific for the T cell receptor V beta gene expressed by the major fraction of MAM-reactive human T cells, V beta 17. In addition, a V beta 17- MAM-reactive T cell population exists, assessed by MAM, induced T cell proliferation and cytotoxic T cell activity. mAb C1 will be useful in characterizing the functional properties of V beta 17+ T cells and their potential role in autoimmune disease.

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