AKAP79-mediated Targeting of the Cyclic AMP-dependent Protein Kinase to the β1-Adrenergic Receptor Promotes Recycling and Functional Resensitization of the Receptor

Lidia A. Gardner; Steven J. Tavalin; April S. Goehring; John D. Scott; Suleiman W. Bahouth

doi:10.1074/jbc.m601809200

AKAP79-mediated Targeting of the Cyclic AMP-dependent Protein Kinase to the β1-Adrenergic Receptor Promotes Recycling and Functional Resensitization of the Receptor

Journal of Biological Chemistry ◽

10.1074/jbc.m601809200 ◽

2006 ◽

Vol 281 (44) ◽

pp. 33537-33553 ◽

Cited By ~ 55

Author(s):

Lidia A. Gardner ◽

Steven J. Tavalin ◽

April S. Goehring ◽

John D. Scott ◽

Suleiman W. Bahouth

Keyword(s):

Protein Kinase ◽

Cyclic Amp ◽

Adrenergic Receptor ◽

Dependent Protein Kinase ◽

Dependent Protein

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The palmitoylation state of the β2-adrenergic receptor regulates the synergistic action of cyclic AMP-dependent protein kinase and β-adrenergic receptor kinase involved in its phosphorylation and desensitization

Journal of Neurochemistry ◽

10.1046/j.1471-4159.2001.00005.x ◽

2008 ◽

Vol 76 (1) ◽

pp. 269-279 ◽

Cited By ~ 39

Author(s):

Serge Moffett ◽

Guy Rousseau ◽

Monique Lagacé ◽

Michel Bouvier

Keyword(s):

Protein Kinase ◽

Cyclic Amp ◽

Adrenergic Receptor ◽

Synergistic Action ◽

Receptor Kinase ◽

Dependent Protein Kinase ◽

Dependent Protein ◽

Β2 Adrenergic Receptor

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Role of the Cyclic AMP-dependent Protein Kinase in Homologous Resensitization of the β1-Adrenergic Receptor

Journal of Biological Chemistry ◽

10.1074/jbc.m313652200 ◽

2004 ◽

Vol 279 (20) ◽

pp. 21135-21143 ◽

Cited By ~ 28

Author(s):

Lidia A. Gardner ◽

Noel M. Delos Santos ◽

Shannon G. Matta ◽

Michael A. Whitt ◽

Suleiman W. Bahouth

Keyword(s):

Protein Kinase ◽

Cyclic Amp ◽

Adrenergic Receptor ◽

Dependent Protein Kinase ◽

Dependent Protein

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β2-Adrenergic Receptor Lacking the Cyclic AMP-Dependent Protein Kinase Consensus Sites Fully Activates Extracellular Signal-Regulated Kinase 1/2 in Human Embryonic Kidney 293 Cells: Lack of Evidence for Gs/GiSwitching.

Molecular Pharmacology ◽

10.1124/mol.62.5.1094 ◽

2002 ◽

Vol 62 (5) ◽

pp. 1094-1102 ◽

Cited By ~ 55

Author(s):

Jacqueline Friedman ◽

Bonita Babu ◽

Richard B. Clark

Keyword(s):

Protein Kinase ◽

Cyclic Amp ◽

Adrenergic Receptor ◽

Human Embryonic Kidney ◽

Dependent Protein Kinase ◽

Extracellular Signal Regulated Kinase ◽

293 Cells ◽

Extracellular Signal ◽

Dependent Protein ◽

Β2 Adrenergic Receptor

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Role of the cyclic AMP-dependent protein kinase in homologous resensitization of the ß1-adrenergic receptor. VOLUME 279 (2004) PAGES 21135-21143

Journal of Biological Chemistry ◽

10.1016/s0021-9258(20)87396-7 ◽

2007 ◽

Vol 282 (26) ◽

pp. 19272

Author(s):

Lidia A. Gardner ◽

Noel M. Delos Santos ◽

Shannon G. Matta ◽

Michael A. Whitt ◽

Suleiman W. Bahouth

Keyword(s):

Protein Kinase ◽

Cyclic Amp ◽

Adrenergic Receptor ◽

Dependent Protein Kinase ◽

Dependent Protein

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Phosphorylation of the mammalian beta-adrenergic receptor by cyclic AMP-dependent protein kinase. Regulation of the rate of receptor phosphorylation and dephosphorylation by agonist occupancy and effects on coupling of the receptor to the stimulatory guanine nucleotide regulatory protein.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)88892-5 ◽

1985 ◽

Vol 260 (11) ◽

pp. 7094-7101 ◽

Cited By ~ 11

Author(s):

J L Benovic ◽

L J Pike ◽

R A Cerione ◽

C Staniszewski ◽

T Yoshimasa ◽

...

Keyword(s):

Protein Kinase ◽

Cyclic Amp ◽

Adrenergic Receptor ◽

Regulatory Protein ◽

Guanine Nucleotide ◽

Beta Adrenergic Receptor ◽

Dependent Protein Kinase ◽

Receptor Phosphorylation ◽

Dependent Protein ◽

Guanine Nucleotide Regulatory Protein

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Comparative rates of desensitization of beta-adrenergic receptors by the beta-adrenergic receptor kinase and the cyclic AMP-dependent protein kinase.

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.88.14.6201 ◽

1991 ◽

Vol 88 (14) ◽

pp. 6201-6204 ◽

Cited By ~ 130

Author(s):

N. S. Roth ◽

P. T. Campbell ◽

M. G. Caron ◽

R. J. Lefkowitz ◽

M. J. Lohse

Keyword(s):

Protein Kinase ◽

Cyclic Amp ◽

Adrenergic Receptors ◽

Adrenergic Receptor ◽

Receptor Kinase ◽

Beta Adrenergic Receptors ◽

Beta Adrenergic Receptor ◽

Dependent Protein Kinase ◽

Beta Adrenergic ◽

Dependent Protein

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Regulation of adrenergic receptor function by phosphorylation. II. Effects of agonist occupancy on phosphorylation of alpha 1- and beta 2-adrenergic receptors by protein kinase C and the cyclic AMP-dependent protein kinase.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)61475-9 ◽

1987 ◽

Vol 262 (7) ◽

pp. 3106-3113 ◽

Cited By ~ 15

Author(s):

M. Bouvier ◽

L.M. Leeb-Lundberg ◽

J.L. Benovic ◽

M.G. Caron ◽

R.J. Lefkowitz

Keyword(s):

Protein Kinase C ◽

Protein Kinase ◽

Cyclic Amp ◽

Adrenergic Receptors ◽

Adrenergic Receptor ◽

Receptor Function ◽

Dependent Protein Kinase ◽

Kinase C ◽

Dependent Protein ◽

Beta 2

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Alterations in activities of cyclic nucleotide systems and in β-adrenergic receptor-mediated activation of cyclic amp-dependent protein kinase during progression and regression of isoproterenol-induced cardiac hypertrophy

Biochimica et Biophysica Acta (BBA) - General Subjects ◽

10.1016/0304-4165(78)90371-9 ◽

1978 ◽

Vol 542 (3) ◽

pp. 399-411 ◽

Cited By ~ 25

Author(s):

James Tse ◽

Nancy L. Brackett ◽

J.F. Kuo

Keyword(s):

Protein Kinase ◽

Cyclic Amp ◽

Cardiac Hypertrophy ◽

Cyclic Nucleotide ◽

Adrenergic Receptor ◽

Dependent Protein Kinase ◽

Dependent Protein

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The ß-adrenergic receptor system in human glioma-derived cell lines: The mode of phosphodiesterase induction and the macromolecules phosphorylated by cyclic AMP-dependent protein kinase

Brain Research ◽

10.1016/0006-8993(84)90511-0 ◽

1984 ◽

Vol 296 (1) ◽

pp. 67-74 ◽

Cited By ~ 7

Author(s):

N. Shitara ◽

T.D. Reisine ◽

H. Nakamura ◽

M. Fujiwara ◽

B.H. Smith ◽

...

Keyword(s):

Protein Kinase ◽

Cyclic Amp ◽

Cell Lines ◽

Adrenergic Receptor ◽

Human Glioma ◽

Dependent Protein Kinase ◽

Receptor System ◽

Dependent Protein

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Cyclic AMP-dependent protein kinase in canine pancreatic rough endoplasmic reticulum

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)84796-8 ◽

1989 ◽

Vol 264 (28) ◽

pp. 16927-16932

Author(s):

S K Nigam ◽

G Blobel

Keyword(s):

Endoplasmic Reticulum ◽

Protein Kinase ◽

Cyclic Amp ◽

Rough Endoplasmic Reticulum ◽

Dependent Protein Kinase ◽

Dependent Protein

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