scholarly journals The Orphan G Protein-coupled Receptors GPR41 and GPR43 Are Activated by Propionate and Other Short Chain Carboxylic Acids

2002 ◽  
Vol 278 (13) ◽  
pp. 11312-11319 ◽  
Author(s):  
Andrew J. Brown ◽  
Susan M. Goldsworthy ◽  
Ashley A. Barnes ◽  
Michelle M. Eilert ◽  
Lili Tcheang ◽  
...  
Keyword(s):  
G Protein ◽  
Carboxylic Acids ◽  
G Protein Coupled Receptors ◽  
Short Chain ◽  
G Protein Coupled

scholarly journals Peran mikrobiota usus dalam perkembangan obesitas

2019 ◽  
Vol 42 (1) ◽  
pp. 41
Author(s):  
Susmiati Susmiati
Keyword(s):  
Fatty Acid ◽  
G Protein ◽  
Short Chain Fatty Acid ◽  
Peptide Yy ◽  
Chain Fatty Acid ◽  
G Protein Coupled Receptors ◽  
Short Chain ◽  
G Protein Coupled

Sampai sekarang etiologi  obesitas masih belum jelas dan masih diperdebatkan. Baru-baru ini mikrobiota usus dianggap sebagai salah satu faktor yang berperan terhadap kejadian obesitas. Tujuan: Untuk membahas tentang peran mikrobiota usus terhadap kejadian obesitas. Metode: Artikel ini disusun berdasarkan review beberapa literature yang berhubungan dengan peran mikrobiota usus baik pada hewan coba maupun pada manusia dengan berbagai metode penelitian. Hasil: Pada penelusuran literature didapatkan  peran mikrobiota usus terhadap kejadian obesitas dapat melalui beberapa mekanisme yaitu melalui jalur metabolik, inflamasi dan hormonal. Jalur metabolik dengan peningkatan produksi Short-Chain Fatty Acid (SCFA), perubahan metabolisme asam empedu dan FXR/TGR5 signaling, jalur inflamasi dengan peningkatan lipopolisakarida (LPS) dan endocannabinoid (eCB) system yang mengatur metabolisme dan rasa lapar melalui microbiota-gut-brain axis serta jalur hormonal yaitu penekanan fiaf, peningkatan Peptide YY (PYY), dan ekspresi dari G protein coupled receptors (GPCRs). Simpulan: Beberapa penelitian menunjukkan mekanisme utama peran mikrobiota terhadap perkembangan obesitas dapat melalui jalur metabolik, inflamasi, maupun hormonal.

scholarly journals Author Correction: Bidirectional regulatory potentials of short-chain fatty acids and their G-protein-coupled receptors in autoimmune neuroinflammation

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Jeongho Park ◽  
Qin Wang ◽  
Qi Wu ◽  
Yang Mao-Draayer ◽  
Chang H. Kim
Keyword(s):  
Fatty Acids ◽  
G Protein ◽  
Short Chain Fatty Acids ◽  
G Protein Coupled Receptors ◽  
Short Chain ◽  
G Protein Coupled ◽  
Chain Fatty Acids

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

Short-Chain Fatty Acids, G Protein-Coupled Receptors, and Immune Cells

2017 ◽  
pp. 279-294
Author(s):  
José Luís Fachi ◽  
Renan O. Corrêa ◽  
Fabio T. Sato ◽  
Angélica T. Vieira ◽  
Hosana G. Rodrigues ◽  
...  
Keyword(s):  
Fatty Acids ◽  
G Protein ◽  
Immune Cells ◽  
Short Chain Fatty Acids ◽  
G Protein Coupled Receptors ◽  
Short Chain ◽  
G Protein Coupled ◽  
Chain Fatty Acids

scholarly journals How Do Short Chain Nonionic Detergents Destabilize G-Protein-Coupled Receptors?

2016 ◽  
Vol 138 (47) ◽  
pp. 15425-15433 ◽  
Author(s):  
Sangbae Lee ◽  
Allen Mao ◽  
Supriyo Bhattacharya ◽  
Nathan Robertson ◽  
Reinhard Grisshammer ◽  
...  
Keyword(s):  
G Protein ◽  
G Protein Coupled Receptors ◽  
Short Chain ◽  
G Protein Coupled ◽  
Nonionic Detergents
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