Src Kinase Mediates Phosphatidylinositol 3-Kinase/Akt-dependent Rapid Endothelial Nitric-oxide Synthase Activation by Estrogen

M. Page Haynes; Lei Li; Diviya Sinha; Kerry S. Russell; Koji Hisamoto; Roland Baron; Mark Collinge; William C. Sessa; Jeffrey R. Bender

doi:10.1074/jbc.m210828200

Src Kinase Mediates Phosphatidylinositol 3-Kinase/Akt-dependent Rapid Endothelial Nitric-oxide Synthase Activation by Estrogen

Journal of Biological Chemistry ◽

10.1074/jbc.m210828200 ◽

2002 ◽

Vol 278 (4) ◽

pp. 2118-2123 ◽

Cited By ~ 216

Author(s):

M. Page Haynes ◽

Lei Li ◽

Diviya Sinha ◽

Kerry S. Russell ◽

Koji Hisamoto ◽

...

Keyword(s):

Nitric Oxide ◽

Nitric Oxide Synthase ◽

Endothelial Nitric Oxide Synthase ◽

Src Kinase ◽

Phosphatidylinositol 3 Kinase ◽

Oxide Synthase ◽

Endothelial Nitric Oxide ◽

Phosphatidylinositol 3

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Up-regulation of Endothelial Nitric-oxide Synthase Promoter by the Phosphatidylinositol 3-Kinase γ/Janus Kinase 2/MEK-1-dependent Pathway

Journal of Biological Chemistry ◽

10.1074/jbc.m005305200 ◽

2000 ◽

Vol 276 (2) ◽

pp. 1211-1219 ◽

Cited By ~ 51

Author(s):

Katarzyna Cieslik ◽

Charles S. Abrams ◽

Kenneth K. Wu

Keyword(s):

Nitric Oxide ◽

Nitric Oxide Synthase ◽

Endothelial Nitric Oxide Synthase ◽

Janus Kinase ◽

Janus Kinase 2 ◽

Phosphatidylinositol 3 Kinase ◽

Oxide Synthase ◽

Endothelial Nitric Oxide ◽

Dependent Pathway ◽

Phosphatidylinositol 3

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Carbon monoxide releasing molecule induces endothelial nitric oxide synthase activation through a calcium and phosphatidylinositol 3-kinase/Akt mechanism

Vascular Pharmacology ◽

10.1016/j.vph.2016.09.010 ◽

2016 ◽

Vol 87 ◽

pp. 209-218 ◽

Cited By ~ 9

Author(s):

Po-Min Yang ◽

Yu-Ting Huang ◽

Yu-Qi Zhang ◽

Chia-Wen Hsieh ◽

Being-Sun Wung

Keyword(s):

Nitric Oxide ◽

Carbon Monoxide ◽

Nitric Oxide Synthase ◽

Endothelial Nitric Oxide Synthase ◽

Phosphatidylinositol 3 Kinase ◽

Oxide Synthase ◽

Endothelial Nitric Oxide ◽

Phosphatidylinositol 3

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Hyperglycemia Inhibits Anesthetic-induced Postconditioning in the Rabbit Heart via Modulation of Phosphatidylinositol-3-kinase/Akt and Endothelial Nitric Oxide Synthase Signaling

Journal of Cardiovascular Pharmacology ◽

10.1097/fjc.0b013e3181d26583 ◽

2010 ◽

Vol 55 (4) ◽

pp. 348-357 ◽

Cited By ~ 40

Author(s):

Jacob Raphael ◽

Yaacov Gozal ◽

Nachum Navot ◽

Zhiyi Zuo

Keyword(s):

Nitric Oxide ◽

Nitric Oxide Synthase ◽

Endothelial Nitric Oxide Synthase ◽

Rabbit Heart ◽

Phosphatidylinositol 3 Kinase ◽

Oxide Synthase ◽

Endothelial Nitric Oxide ◽

Phosphatidylinositol 3

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Dietary Salt Activates an Endothelial Proline-Rich Tyrosine Kinase 2/c-Src/Phosphatidylinositol 3-Kinase Complex to Promote Endothelial Nitric Oxide Synthase Phosphorylation

Hypertension ◽

10.1161/hypertensionaha.108.121582 ◽

2008 ◽

Vol 52 (6) ◽

pp. 1134-1141 ◽

Cited By ~ 13

Author(s):

Wei-Zhong Ying ◽

Kristal Aaron ◽

Paul W. Sanders

Keyword(s):

Nitric Oxide ◽

Nitric Oxide Synthase ◽

Tyrosine Kinase ◽

Endothelial Nitric Oxide Synthase ◽

Dietary Salt ◽

Phosphatidylinositol 3 Kinase ◽

Tyrosine Kinase 2 ◽

Oxide Synthase ◽

Endothelial Nitric Oxide ◽

Phosphatidylinositol 3

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Phosphorylation of Endothelial Nitric-Oxide Synthase Is Diminished in Mesenteric Arteries from Septic Rabbits Depending on the Altered Phosphatidylinositol 3-Kinase/Akt Pathway: Reversal Effect of Fluvastatin Therapy

Journal of Pharmacology and Experimental Therapeutics ◽

10.1124/jpet.106.109785 ◽

2006 ◽

Vol 319 (3) ◽

pp. 1348-1354 ◽

Cited By ~ 41

Author(s):

Naoyuki Matsuda ◽

Yukio Hayashi ◽

Yoshika Takahashi ◽

Yuichi Hattori

Keyword(s):

Nitric Oxide ◽

Nitric Oxide Synthase ◽

Endothelial Nitric Oxide Synthase ◽

Mesenteric Arteries ◽

Akt Pathway ◽

Phosphatidylinositol 3 Kinase ◽

Reversal Effect ◽

Oxide Synthase ◽

Endothelial Nitric Oxide ◽

Phosphatidylinositol 3

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Nitroglycerin drives endothelial nitric oxide synthase activation via the phosphatidylinositol 3-kinase/protein kinase B pathway

Free Radical Biology and Medicine ◽

10.1016/j.freeradbiomed.2011.09.020 ◽

2012 ◽

Vol 52 (2) ◽

pp. 427-435 ◽

Cited By ~ 18

Author(s):

Mao Mao ◽

Varadarajan Sudhahar ◽

Kristine Ansenberger-Fricano ◽

Denise C. Fernandes ◽

Leonardo Y. Tanaka ◽

...

Keyword(s):

Nitric Oxide ◽

Protein Kinase ◽

Nitric Oxide Synthase ◽

Endothelial Nitric Oxide Synthase ◽

Protein Kinase B ◽

Phosphatidylinositol 3 Kinase ◽

Oxide Synthase ◽

Endothelial Nitric Oxide ◽

Phosphatidylinositol 3

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dl-3n-Butylphthalide Promotes Angiogenesis Via the Extracellular Signal-regulated Kinase 1/2 and Phosphatidylinositol 3-Kinase/Akt-endothelial Nitric Oxide Synthase Signaling Pathways

Journal of Cardiovascular Pharmacology ◽

10.1097/fjc.0b013e3182443e74 ◽

2012 ◽

Vol 59 (4) ◽

pp. 352-362 ◽

Cited By ~ 20

Author(s):

Xi-lin Lu ◽

Dan Luo ◽

Xiao-li Yao ◽

Guang-lei Wang ◽

Zhi-yong Liu ◽

...

Keyword(s):

Nitric Oxide ◽

Nitric Oxide Synthase ◽

Signaling Pathways ◽

Endothelial Nitric Oxide Synthase ◽

Phosphatidylinositol 3 Kinase ◽

Extracellular Signal Regulated Kinase ◽

Extracellular Signal ◽

Oxide Synthase ◽

Endothelial Nitric Oxide ◽

Phosphatidylinositol 3

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HYPERINSULINAEMIA INCREASES THE GENE EXPRESSION OF ENDOTHELIAL NITRIC OXIDE SYNTHASE AND THE PHOSPHATIDYLINOSITOL 3-KINASE/AKT PATHWAY IN RAT AORTA

Clinical and Experimental Pharmacology and Physiology ◽

10.1111/j.1440-1681.2006.04385.x ◽

2006 ◽

Vol 33 (5-6) ◽

pp. 440-447 ◽

Cited By ~ 10

Author(s):

Hiroe Toba ◽

Eriko Gomyo ◽

Shunsuke Miki ◽

Takahiro Shimizu ◽

Akiko Yoshimura ◽

...

Keyword(s):

Gene Expression ◽

Nitric Oxide ◽

Nitric Oxide Synthase ◽

Endothelial Nitric Oxide Synthase ◽

Rat Aorta ◽

Akt Pathway ◽

Phosphatidylinositol 3 Kinase ◽

Oxide Synthase ◽

Endothelial Nitric Oxide ◽

Phosphatidylinositol 3

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Calcium- and phosphatidylinositol 3-kinase/Akt-dependent activation of endothelial nitric oxide synthase by apigenin

Life Sciences ◽

10.1016/j.lfs.2010.10.014 ◽

2010 ◽

Vol 87 (23-26) ◽

pp. 743-749 ◽

Cited By ~ 19

Author(s):

Chien-Chung Chen ◽

Wen-Hsing Ke ◽

Li-Han Ceng ◽

Chia-Wen Hsieh ◽

Being-Sun Wung

Keyword(s):

Nitric Oxide ◽

Nitric Oxide Synthase ◽

Endothelial Nitric Oxide Synthase ◽

Phosphatidylinositol 3 Kinase ◽

Oxide Synthase ◽

Endothelial Nitric Oxide ◽

Phosphatidylinositol 3

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Faculty Opinions recommendation of Hyperglycemia inhibits anesthetic-induced postconditioning in the rabbit heart via modulation of phosphatidylinositol-3-kinase/Akt and endothelial nitric oxide synthase signaling.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.3435961.3129060 ◽

2010 ◽

Author(s):

Yukio Hayashi

Keyword(s):

Nitric Oxide ◽

Nitric Oxide Synthase ◽

Endothelial Nitric Oxide Synthase ◽

Rabbit Heart ◽

Phosphatidylinositol 3 Kinase ◽

Oxide Synthase ◽

Endothelial Nitric Oxide ◽

Phosphatidylinositol 3

Download Full-text