scholarly journals Effects of altered sialic acid biosynthesis onN-linked glycan branching and cell surface interactions

2017 ◽  
Vol 292 (23) ◽  
pp. 9637-9651 ◽  
Author(s):  
Nam D. Pham ◽  
Poh-Choo Pang ◽  
Soumya Krishnamurthy ◽  
Amberlyn M. Wands ◽  
Paola Grassi ◽  
...  
2012 ◽  
Vol 8 ◽  
pp. 1601-1609 ◽  
Author(s):  
Davide Esposito ◽  
Mattan Hurevich ◽  
Bastien Castagner ◽  
Cheng-Chung Wang ◽  
Peter H Seeberger

Sialic acid-containing glycans play a major role in cell-surface interactions with external partners such as cells and viruses. Straightforward access to sialosides is required in order to study their biological functions on a molecular level. Here, automated oligosaccharide synthesis was used to facilitate the preparation of this class of biomolecules. Our strategy relies on novel sialyl α-(2→3) and α-(2→6) galactosyl imidates, which, used in combination with the automated platform, provided rapid access to a small library of conjugation-ready sialosides of biological relevance.


1984 ◽  
Vol 259 (15) ◽  
pp. 9440-9446
Author(s):  
R L Goldberg ◽  
J D Seidman ◽  
G Chi-Rosso ◽  
B P Toole

Biomaterials ◽  
2009 ◽  
Vol 30 (9) ◽  
pp. 1827-1850 ◽  
Author(s):  
Martin A. Cole ◽  
Nicolas H. Voelcker ◽  
Helmut Thissen ◽  
Hans J. Griesser

Perfusion ◽  
2013 ◽  
Vol 28 (3) ◽  
pp. 263-271 ◽  
Author(s):  
G Johnson ◽  
B Curry ◽  
L Cahalan ◽  
R Prater ◽  
J Biggerstaff ◽  
...  

2021 ◽  
Vol 153 ◽  
pp. 106120
Author(s):  
Marcia Domínguez ◽  
Rafael Zarzuela ◽  
Ignacio Moreno-Garrido ◽  
María Carbú ◽  
Jesús M. Cantoral ◽  
...  

1984 ◽  
Vol 4 (4) ◽  
pp. 681-687
Author(s):  
B Love ◽  
M B Rotheim

Tetrahymena ciliary membrane vesicles are shown to interact with preconjugant cells in a mating type-specific way. When cells are treated with vesicles of a different mating type before mixing for conjugation, cell pairing is enhanced, and the normal prepairing period is partially eliminated. This enhancement is mating type specific since it is not observed after pretreatment of cells with vesicles of their own mating type. In contrast, when vesicles are added at the time of mixing of two starved cultures, cell pairing is delayed in a concentration-dependent manner. By varying the conditions, we demonstrated enhancement or inhibition, or both. These results are interpreted in terms of two independent interactions of cells with vesicles. We suggest that first, vesicles substitute for another cell in cell-cell prepairing interaction and second, vesicles compete for adhesion sites produced during the prepairing period. Finally, the data presented are summarized within a speculative framework that calls attention to potential analogies with hormone-receptor signaling in mammalian cells.


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