scholarly journals Post-translational Modifications near the Quinone Binding Site of Mammalian Complex I

2013 ◽  
Vol 288 (34) ◽  
pp. 24799-24808 ◽  
Author(s):  
Joe Carroll ◽  
Shujing Ding ◽  
Ian M. Fearnley ◽  
John E. Walker
Keyword(s):  
Binding Site ◽  
Complex I ◽  
Post Translational Modifications ◽  
Quinone Binding

scholarly journals Structure of the NDH-2 – HQNO inhibited complex provides molecular insight into quinone-binding site inhibitors

2018 ◽  
Vol 1859 (7) ◽  
pp. 482-490 ◽  
Author(s):  
Jessica Petri ◽  
Yosuke Shimaki ◽  
Wanting Jiao ◽  
Hannah R. Bridges ◽  
Euan R. Russell ◽  
...  
Keyword(s):  
Binding Site ◽  
Quinone Binding ◽  
Insight Into

Molecular Modelling of the Interaction of Cyanoacrylate Inhibitors with Photosystem II Part 2. The Effect of Stereochemistry of Inhibitor Binding

1993 ◽  
Vol 48 (9-10) ◽  
pp. 782-787 ◽  
Author(s):  
Simon P. Mackay ◽  
Patrick J. O’Malley
Keyword(s):  
Electron Transfer ◽  
Photosystem Ii ◽  
Binding Site ◽  
Energy Minimization ◽  
Electrostatic Interactions ◽  
D1 Protein ◽  
Spatial Arrangement ◽  
Inhibitor Binding ◽  
Protein Residues ◽  
Quinone Binding

Abstract The 2-cyanoacrylate inhibitors are a potent class of herbicides which block electron transfer in photosystem II. The spatial arrangement of different functional groups are an important factor in determining activity and a number of derivatives have been used as stereospecific probes of the secondary quinone binding site. More than one region of stereoselectivity in the binding site has been identified which influences the interaction with specific groups of the inhibitor. We have studied the interaction of various stereoisomers of the cyanoacrylates with the binding site in the D1 protein (residues Leu 210 to Val 280) by determining the nonbonded intermolecular energies between the modelled structures calculated by van der Waals and electrostatic interactions after energy minimization of the combined structures to reduce inter and intramolecular strain and have found that the results reflect the experimentally determined data

scholarly journals Electron transfer activity through the quinone-binding site of complex II (succinate: Quinone reductase)

2010 ◽  
Vol 1797 ◽  
pp. 111
Author(s):  
Gary Cecchini ◽  
Elena Maklashina ◽  
Sujata S. Shinde ◽  
Robert F. Anderson ◽  
Russ Hille
Keyword(s):  
Electron Transfer ◽  
Binding Site ◽  
Quinone Reductase ◽  
Complex Ii ◽  
Transfer Activity ◽  
Quinone Binding
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