scholarly journals PhyscomitrellaPpORS, Basal to Plant Type III Polyketide Synthases in Phylogenetic Trees, Is a Very Long Chain 2′-Oxoalkylresorcinol Synthase

2012 ◽  
Vol 288 (4) ◽  
pp. 2767-2777 ◽  
Author(s):  
Sun Young Kim ◽  
Che C. Colpitts ◽  
Gertrud Wiedemann ◽  
Christina Jepson ◽  
Mehrieh Rahimi ◽  
...  
Keyword(s):  
Phylogenetic Trees ◽  
Polyketide Synthases ◽  
Plant Type ◽  
Type Iii ◽  
Long Chain

Enzymatic formation of long-chain polyketide pyrones by plant type III polyketide synthases

2004 ◽  
Vol 65 (17) ◽  
pp. 2447-2453 ◽  
Author(s):  
Ikuro Abe ◽  
Tatsuya Watanabe ◽  
Hiroshi Noguchi
Keyword(s):  
Polyketide Synthases ◽  
Plant Type ◽  
Type Iii ◽  
Enzymatic Formation ◽  
Long Chain

Optimisation of a fungal bioluminescence system by plant type III polyketide synthases

2019 ◽  
Vol 305 ◽  
pp. S50
Author(s):  
K.A. Palkina ◽  
N.M. Markina ◽  
K.S. Sarkisyan ◽  
I.V. Yampolsky
Keyword(s):  
Polyketide Synthases ◽  
Plant Type ◽  
Type Iii

Covalent binding of chloroacetamide herbicides to the active site cysteine of plant type III polyketide synthases

2003 ◽  
Vol 64 (6) ◽  
pp. 1045-1054 ◽  
Author(s):  
Christian Eckermann ◽  
Bernd Matthes ◽  
Manfred Nimtz ◽  
Verena Reiser ◽  
Barbara Lederer ◽  
...  
Keyword(s):  
Active Site ◽  
Covalent Binding ◽  
Polyketide Synthases ◽  
Plant Type ◽  
Type Iii ◽  
Active Site Cysteine

scholarly journals An Overview of the Medicinally Important Plant Type III PKS Derived Polyketides

2021 ◽  
Vol 12 ◽  
Author(s):  
Renu Bisht ◽  
Aniket Bhattacharyya ◽  
Ankita Shrivastava ◽  
Priti Saxena
Keyword(s):  
Secondary Metabolites ◽  
Industrial Applications ◽  
Polyketide Synthases ◽  
Instrumental Effects ◽  
Growth Phases ◽  
Plant Type ◽  
Type Iii ◽  
Broad Array ◽  
Human Use ◽  
Structural Simplicity

Plants produce interesting secondary metabolites that are a valuable source of both medicines for human use, along with significant advantages for the manufacturer species. The active compounds which lead to these instrumental effects are generally secondary metabolites produced during various plant growth phases, which provide the host survival advantages while affecting human health inadvertently. Different chemical classes of secondary metabolites are biosynthesized by the plant type III polyketide synthases (PKSs). They are simple homodimeric proteins with the unique mechanistic potential to produce a broad array of secondary metabolites by utilizing simpler starter and extender units. These PKS derived products are majorly the precursors of some important secondary metabolite pathways leading to products such as flavonoids, stilbenes, benzalacetones, chromones, acridones, xanthones, cannabinoids, aliphatic waxes, alkaloids, anthrones, and pyrones. These secondary metabolites have various pharmaceutical, medicinal and industrial applications which make biosynthesizing type III PKSs an important tool for bioengineering purposes. Because of their structural simplicity and ease of manipulation, these enzymes have garnered interest in recent years due to their application in the generation of unnatural natural polyketides and modified products in the search for newer drugs for a variety of health problems. The following review covers the biosynthesis of a variety of type III PKS-derived secondary metabolites, their biological relevance, the associated enzymes, and recent research.

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