Insulin Growth Factor-2 Binding Protein 3 (IGF2BP3) Is a Glioblastoma-specific Marker That Activates Phosphatidylinositol 3-Kinase/Mitogen-activated Protein Kinase (PI3K/MAPK) Pathways by Modulating IGF-2

Ramaswamy Suvasini; Bhargava Shruti; Balaram Thota; Sridevi Vijay Shinde; Dinorah Friedmann-Morvinski; Zahid Nawaz; Krishnarao Venkatesh Prasanna; Kandavel Thennarasu; Alangar Sathyaranjandas Hegde; Arimappamagan Arivazhagan; Bangalore Ashwathnarayanarao Chandramouli; Vani Santosh; Kumaravel Somasundaram

doi:10.1074/jbc.m110.178012

Insulin Growth Factor-2 Binding Protein 3 (IGF2BP3) Is a Glioblastoma-specific Marker That Activates Phosphatidylinositol 3-Kinase/Mitogen-activated Protein Kinase (PI3K/MAPK) Pathways by Modulating IGF-2

Journal of Biological Chemistry ◽

10.1074/jbc.m110.178012 ◽

2011 ◽

Vol 286 (29) ◽

pp. 25882-25890 ◽

Cited By ~ 81

Author(s):

Ramaswamy Suvasini ◽

Bhargava Shruti ◽

Balaram Thota ◽

Sridevi Vijay Shinde ◽

Dinorah Friedmann-Morvinski ◽

...

Keyword(s):

Growth Factor ◽

Protein Kinase ◽

Binding Protein ◽

Mitogen Activated Protein Kinase ◽

Specific Marker ◽

Phosphatidylinositol 3 Kinase ◽

Insulin Growth Factor ◽

Mapk Pathways ◽

Mitogen Activated Protein ◽

Phosphatidylinositol 3

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Basic fibroblast growth factor enhances proliferation of human rhabdosphincter cells via mitogen-activated protein kinase and phosphatidylinositol 3-kinase

European Urology Supplements ◽

10.1016/s1569-9056(03)80362-7 ◽

2003 ◽

Vol 2 (1) ◽

pp. 91

Author(s):

H. Mimata ◽

Y. Hirata ◽

A. Emoto ◽

T. Shin ◽

T. Matsubara ◽

...

Keyword(s):

Growth Factor ◽

Protein Kinase ◽

Fibroblast Growth Factor ◽

Basic Fibroblast Growth Factor ◽

Mitogen Activated Protein Kinase ◽

Fibroblast Growth ◽

Phosphatidylinositol 3 Kinase ◽

Mitogen Activated Protein ◽

Phosphatidylinositol 3

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Anti-apoptotic signaling by hepatocyte growth factor/Met via the phosphatidylinositol 3-kinase/Akt and mitogen-activated protein kinase pathways

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.98.1.247 ◽

2001 ◽

Vol 98 (1) ◽

pp. 247-252 ◽

Cited By ~ 215

Author(s):

G.-H. Xiao ◽

M. Jeffers ◽

A. Bellacosa ◽

Y. Mitsuuchi ◽

G. F. Vande Woude ◽

...

Keyword(s):

Growth Factor ◽

Protein Kinase ◽

Hepatocyte Growth Factor ◽

Mitogen Activated Protein Kinase ◽

Phosphatidylinositol 3 Kinase ◽

Apoptotic Signaling ◽

Mitogen Activated Protein ◽

Hepatocyte Growth ◽

Phosphatidylinositol 3

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Mitogen-Activated Protein Kinase and Phosphatidylinositol 3-Kinase Pathways Are Not Sufficient for Insulin-Like Growth Factor I-Induced Mitogenesis and Tumorigenesis

Endocrinology ◽

10.1210/endo.138.6.5215 ◽

1997 ◽

Vol 138 (6) ◽

pp. 2552-2558 ◽

Cited By ~ 15

Author(s):

Angus G. Scrimgeour ◽

Vicky A. Blakesley ◽

Bethel S. Stannard ◽

Derek LeRoith

Keyword(s):

Growth Factor ◽

Protein Kinase ◽

Mitogen Activated Protein Kinase ◽

Insulin Like Growth Factor ◽

Phosphatidylinositol 3 Kinase ◽

Factor I ◽

Mitogen Activated Protein ◽

Growth Factor I ◽

Phosphatidylinositol 3

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CAAX Peptidomimetic FTI-244 Decreases Platelet-Derived Growth Factor Receptor Tyrosine Phosphorylation Levels and Inhibits Stimulation of Phosphatidylinositol 3-Kinase but Not Mitogen-Activated Protein Kinase

Biochemical and Biophysical Research Communications ◽

10.1006/bbrc.1995.2287 ◽

1995 ◽

Vol 214 (1) ◽

pp. 295-303 ◽

Cited By ~ 13

Author(s):

T.F. Mcguire ◽

Y.M. Qian ◽

M.A. Blaskovich ◽

R.D. Fossum ◽

J.Z. Sun ◽

...

Keyword(s):

Growth Factor ◽

Protein Kinase ◽

Tyrosine Phosphorylation ◽

Growth Factor Receptor ◽

Mitogen Activated Protein Kinase ◽

Platelet Derived Growth Factor ◽

Phosphatidylinositol 3 Kinase ◽

Mitogen Activated Protein ◽

Stimulation Of ◽

Phosphatidylinositol 3

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Epidermal Growth Factor Induces Vasoconstriction Through the Phosphatidylinositol 3-Kinase-Mediated Mitogen-Activated Protein Kinase Pathway in Hypertensive Rats

Journal of Pharmacological Sciences ◽

10.1254/jphs.fp0060021 ◽

2006 ◽

Vol 101 (2) ◽

pp. 135-143 ◽

Cited By ~ 33

Author(s):

Junghwan Kim ◽

Chang-Kwon Lee ◽

Hyo-Jun Park ◽

Hyo Jin Kim ◽

Hyun Ha So ◽

...

Keyword(s):

Growth Factor ◽

Protein Kinase ◽

Epidermal Growth Factor ◽

Mitogen Activated Protein Kinase ◽

Phosphatidylinositol 3 Kinase ◽

Hypertensive Rats ◽

Mitogen Activated Protein ◽

Epidermal Growth ◽

Kinase Pathway ◽

Phosphatidylinositol 3

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Insulin-like Growth Factor 1 Inhibits Apoptosis Using the Phosphatidylinositol 3′-Kinase and Mitogen-activated Protein Kinase Pathways

Journal of Biological Chemistry ◽

10.1074/jbc.272.1.154 ◽

1997 ◽

Vol 272 (1) ◽

pp. 154-161 ◽

Cited By ~ 449

Author(s):

Marcelina Párrizas ◽

Alan R. Saltiel ◽

Derek LeRoith

Keyword(s):

Growth Factor ◽

Protein Kinase ◽

Mitogen Activated Protein Kinase ◽

Insulin Like Growth Factor ◽

Phosphatidylinositol 3 Kinase ◽

Mitogen Activated Protein ◽

Phosphatidylinositol 3

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Both mitogen-activated protein kinase and phosphatidylinositol 3-kinase signalling are required in epidermal growth factor-induced human trophoblast migration

MHR Basic science of reproductive medicine ◽

10.1093/molehr/gah088 ◽

2004 ◽

Vol 10 (9) ◽

pp. 677-684 ◽

Cited By ~ 86

Author(s):

Q. Qiu

Keyword(s):

Growth Factor ◽

Protein Kinase ◽

Epidermal Growth Factor ◽

Mitogen Activated Protein Kinase ◽

Phosphatidylinositol 3 Kinase ◽

Human Trophoblast ◽

Mitogen Activated Protein ◽

Epidermal Growth ◽

Trophoblast Migration ◽

Phosphatidylinositol 3

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Activation of Rac1 by phosphatidylinositol 3-kinase in vivo: role in activation of mitogen-activated protein kinase (MAPK) pathways and retinoic acid-induced neuronal differentiation of SH-SY5Y cells

Journal of Neurochemistry ◽

10.1111/j.1471-4159.2005.03106.x ◽

2005 ◽

Vol 93 (3) ◽

pp. 571-583 ◽

Cited By ~ 70

Author(s):

Jing Pan ◽

Yu-Lin Kao ◽

Suchitra Joshi ◽

Seena Jeetendran ◽

Donald DiPette ◽

...

Keyword(s):

Retinoic Acid ◽

Protein Kinase ◽

Neuronal Differentiation ◽

Mitogen Activated Protein Kinase ◽

Phosphatidylinositol 3 Kinase ◽

Mapk Pathways ◽

Mitogen Activated Protein ◽

Phosphatidylinositol 3

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Response of Subcutaneous Xenografts of Endometrial Cancer in Nude Mice to Inhibitors of Phosphatidylinositol 3-Kinase/Akt and Mitogen-Activated Protein Kinase (MAPK) Pathways: An Effective Therapeutic Strategy for Endometrial Cancer

Journal of Cancer Therapy ◽

10.4236/jct.2015.612118 ◽

2015 ◽

Vol 06 (12) ◽

pp. 1083-1092

Author(s):

Ruixia Guo ◽

Xinyan Wang ◽

Ruifang Zhang ◽

Huirong Shi ◽

Yuhuan Qiao ◽

...

Keyword(s):

Endometrial Cancer ◽

Protein Kinase ◽

Nude Mice ◽

Therapeutic Strategy ◽

Mitogen Activated Protein Kinase ◽

Phosphatidylinositol 3 Kinase ◽

Mapk Pathways ◽

Mitogen Activated Protein ◽

Effective Therapeutic Strategy ◽

Phosphatidylinositol 3

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Anchorage-Independent Activation of Mitogen-Activated Protein Kinase through Phosphatidylinositol-3 Kinase by Insulin-like Growth Factor I

Biochemical and Biophysical Research Communications ◽

10.1006/bbrc.2000.2737 ◽

2000 ◽

Vol 272 (1) ◽

pp. 111-115 ◽

Cited By ~ 14

Author(s):

Katsuo Suzuki ◽

Kazuhide Takahashi

Keyword(s):

Growth Factor ◽

Protein Kinase ◽

Mitogen Activated Protein Kinase ◽

Insulin Like Growth Factor ◽

Phosphatidylinositol 3 Kinase ◽

Factor I ◽

Mitogen Activated Protein ◽

Growth Factor I ◽

Phosphatidylinositol 3

Download Full-text