Hypochlorite-modified Low Density Lipoprotein Inhibits Nitric Oxide Synthesis in Endothelial Cells via an Intracellular Dislocalization of Endothelial Nitric-oxide Synthase

Alexander Nuszkowski; Rolf Gräbner; Gunther Marsche; Anett Unbehaun; Ernst Malle; Regine Heller

doi:10.1074/jbc.m007659200

Hypochlorite-modified Low Density Lipoprotein Inhibits Nitric Oxide Synthesis in Endothelial Cells via an Intracellular Dislocalization of Endothelial Nitric-oxide Synthase

Journal of Biological Chemistry ◽

10.1074/jbc.m007659200 ◽

2001 ◽

Vol 276 (17) ◽

pp. 14212-14221 ◽

Cited By ~ 82

Author(s):

Alexander Nuszkowski ◽

Rolf Gräbner ◽

Gunther Marsche ◽

Anett Unbehaun ◽

Ernst Malle ◽

...

Keyword(s):

Nitric Oxide ◽

Endothelial Cells ◽

Nitric Oxide Synthase ◽

Endothelial Nitric Oxide Synthase ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Nitric Oxide Synthesis ◽

Oxide Synthase ◽

Endothelial Nitric Oxide

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Oxidized Low-density Lipoprotein Decreases the Expression of Endothelial Nitric Oxide Synthase

Journal of Biological Chemistry ◽

10.1074/jbc.270.1.319 ◽

1995 ◽

Vol 270 (1) ◽

pp. 319-324 ◽

Cited By ~ 371

Author(s):

James K. Liao ◽

Wee Soo Shin ◽

Wen Yee Lee ◽

Stephen L. Clark

Keyword(s):

Nitric Oxide ◽

Nitric Oxide Synthase ◽

Endothelial Nitric Oxide Synthase ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Oxidized Low Density Lipoprotein ◽

Oxide Synthase ◽

Endothelial Nitric Oxide

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Heterogeneity in hand veins responses to acetylcholine is not associated with polymorphisms in the G-protein ß3-subunit (C825T) and endothelial nitric oxide synthase (G894T) genes but with serum low density lipoprotein cholesterol

Pharmacogenetics ◽

10.1097/00008571-200106000-00005 ◽

2001 ◽

Vol 11 (4) ◽

pp. 307-316 ◽

Cited By ~ 12

Author(s):

Matthias Grossmann ◽

Dobromir Dobrev ◽

Winfried Siffert ◽

Wilhelm Kirch

Keyword(s):

Nitric Oxide ◽

Nitric Oxide Synthase ◽

G Protein ◽

Endothelial Nitric Oxide Synthase ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Low Density Lipoprotein Cholesterol ◽

Oxide Synthase ◽

Endothelial Nitric Oxide

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Oxidized low density lipoprotein impairs endothelial progenitor cells by regulation of endothelial nitric oxide synthase

The Journal of Lipid Research ◽

10.1194/jlr.m500507-jlr200 ◽

2006 ◽

Vol 47 (6) ◽

pp. 1227-1237 ◽

Cited By ~ 111

Author(s):

Feng Xia Ma ◽

Bin Zhou ◽

Zhong Chen ◽

Qian Ren ◽

Shi Hong Lu ◽

...

Keyword(s):

Nitric Oxide ◽

Nitric Oxide Synthase ◽

Progenitor Cells ◽

Endothelial Nitric Oxide Synthase ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Oxidized Low Density Lipoprotein ◽

Oxide Synthase ◽

Endothelial Nitric Oxide

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Oxidized low-density lipoprotein increases superoxide production by endothelial nitric oxide synthase by inhibiting PKC?

Cardiovascular Research ◽

10.1016/j.cardiores.2004.11.003 ◽

2005 ◽

Vol 65 (4) ◽

pp. 897-906 ◽

Cited By ~ 82

Author(s):

I FLEMING ◽

A MOHAMED ◽

J GALLE ◽

L TURCHANOWA ◽

R BRANDES ◽

...

Keyword(s):

Nitric Oxide ◽

Nitric Oxide Synthase ◽

Endothelial Nitric Oxide Synthase ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Superoxide Production ◽

Low Density ◽

Oxidized Low Density Lipoprotein ◽

Oxide Synthase ◽

Endothelial Nitric Oxide

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Oxidized Low Density Lipoprotein Displaces Endothelial Nitric-oxide Synthase (eNOS) from Plasmalemmal Caveolae and Impairs eNOS Activation

Journal of Biological Chemistry ◽

10.1074/jbc.274.45.32512 ◽

1999 ◽

Vol 274 (45) ◽

pp. 32512-32519 ◽

Cited By ~ 247

Author(s):

Alison Blair ◽

Philip W. Shaul ◽

Ivan S. Yuhanna ◽

Patricia A. Conrad ◽

Eric J. Smart

Keyword(s):

Nitric Oxide ◽

Nitric Oxide Synthase ◽

Endothelial Nitric Oxide Synthase ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Oxidized Low Density Lipoprotein ◽

Oxide Synthase ◽

Endothelial Nitric Oxide

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Mulberry and its main components protect against oxidized low-density lipoprotein-induced endothelial nitric oxide synthase uncoupling

Journal of Functional Foods ◽

10.1016/j.jff.2016.12.034 ◽

2017 ◽

Vol 29 ◽

pp. 295-302 ◽

Cited By ~ 4

Author(s):

Hwa-Young Lee ◽

Mi-Ra Oh ◽

Eun-Soo Jung ◽

Yang-Soo Lee ◽

Deok-Su Kim ◽

...

Keyword(s):

Nitric Oxide ◽

Nitric Oxide Synthase ◽

Endothelial Nitric Oxide Synthase ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Oxidized Low Density Lipoprotein ◽

Main Components ◽

Oxide Synthase ◽

Endothelial Nitric Oxide

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Caveolin-1 Regulates Atherogenesis by Attenuating Low-Density Lipoprotein Transcytosis and Vascular Inflammation Independently of Endothelial Nitric Oxide Synthase Activation

Circulation ◽

10.1161/circulationaha.118.038571 ◽

2019 ◽

Vol 140 (3) ◽

pp. 225-239 ◽

Cited By ~ 16

Author(s):

Cristina M. Ramírez ◽

Xinbo Zhang ◽

Chirosree Bandyopadhyay ◽

Noemi Rotllan ◽

Michael G. Sugiyama ◽

...

Keyword(s):

Nitric Oxide ◽

Nitric Oxide Synthase ◽

Endothelial Nitric Oxide Synthase ◽

Vascular Inflammation ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Caveolin 1 ◽

Oxide Synthase ◽

Endothelial Nitric Oxide

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High Density Lipoprotein Prevents Oxidized Low Density Lipoprotein-induced Inhibition of Endothelial Nitric-oxide Synthase Localization and Activation in Caveolae

Journal of Biological Chemistry ◽

10.1074/jbc.275.15.11278 ◽

2000 ◽

Vol 275 (15) ◽

pp. 11278-11283 ◽

Cited By ~ 234

Author(s):

Annette Uittenbogaard ◽

Philip W. Shaul ◽

Ivan S. Yuhanna ◽

Alison Blair ◽

Eric J. Smart

Keyword(s):

Nitric Oxide ◽

Nitric Oxide Synthase ◽

High Density Lipoprotein ◽

Endothelial Nitric Oxide Synthase ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Oxidized Low Density Lipoprotein ◽

Oxide Synthase ◽

Endothelial Nitric Oxide

Download Full-text

Effects of incretin agonists on endothelial nitric oxide synthase expression and nitric oxide synthesis in human coronary artery endothelial cells exposed to TNFα and glycated albumin

Pharmacological Reports ◽

10.1016/j.pharep.2014.08.007 ◽

2015 ◽

Vol 67 (1) ◽

pp. 69-77 ◽

Cited By ~ 6

Author(s):

Wojciech Garczorz ◽

Tomasz Francuz ◽

Krzysztof Siemianowicz ◽

Agnieszka Kosowska ◽

Agnieszka Kłych ◽

...

Keyword(s):

Nitric Oxide ◽

Endothelial Cells ◽

Coronary Artery ◽

Nitric Oxide Synthase ◽

Endothelial Nitric Oxide Synthase ◽

Glycated Albumin ◽

Nitric Oxide Synthesis ◽

Human Coronary Artery ◽

Oxide Synthase ◽

Endothelial Nitric Oxide

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Pomegranate juice reduces oxidized low-density lipoprotein downregulation of endothelial nitric oxide synthase in human coronary endothelial cells

Nitric Oxide ◽

10.1016/j.niox.2005.12.004 ◽

2006 ◽

Vol 15 (3) ◽

pp. 259-263 ◽

Cited By ~ 33

Author(s):

Filomena de Nigris ◽

Sharon Williams-Ignarro ◽

Chiara Botti ◽

Vincenzo Sica ◽

Louis J. Ignarro ◽

...

Keyword(s):

Nitric Oxide ◽

Endothelial Nitric Oxide Synthase ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Pomegranate Juice ◽

Low Density ◽

Oxidized Low Density Lipoprotein ◽

Coronary Endothelial Cells ◽

Oxide Synthase ◽

Endothelial Nitric Oxide

Download Full-text