scholarly journals Reduction of Sphingomyelin Level without Accumulation of Ceramide in Chinese Hamster Ovary Cells Affects Detergent-resistant Membrane Domains and Enhances Cellular Cholesterol Efflux to Methyl-β-cyclodextrin

2000 ◽  
Vol 275 (44) ◽  
pp. 34028-34034 ◽  
Author(s):  
Masayoshi Fukasawa ◽  
Masahiro Nishijima ◽  
Hiroyuki Itabe ◽  
Tatsuya Takano ◽  
Kentaro Hanada
Keyword(s):  
Chinese Hamster Ovary ◽  
Cholesterol Efflux ◽  
Chinese Hamster Ovary Cells ◽  
Chinese Hamster ◽  
Membrane Domains ◽  
Cellular Cholesterol ◽  
Ovary Cells ◽  
Cellular Cholesterol Efflux ◽  
Detergent Resistant Membrane

scholarly journals Enhanced ApoA-I-dependent Cholesterol Efflux by ABCA1 from Sphingomyelin-deficient Chinese Hamster Ovary Cells

2007 ◽  
Vol 282 (20) ◽  
pp. 14868-14874 ◽  
Author(s):  
Kohjiro Nagao ◽  
Kei Takahashi ◽  
Kentaro Hanada ◽  
Noriyuki Kioka ◽  
Michinori Matsuo ◽  
...  
Keyword(s):  
Chinese Hamster Ovary ◽  
Cholesterol Efflux ◽  
Chinese Hamster Ovary Cells ◽  
Chinese Hamster ◽  
Ovary Cells

Malignancy-related characteristics of wild type and drug-resistant chinese hamster ovary cells

Pathology ◽  
1993 ◽  
Vol 25 (3) ◽  
pp. 268-276 ◽  
Author(s):  
Wanda B. Mackinnon ◽  
Marlen Dyne ◽  
Rebecca Hancock ◽  
Carolyn E. Mountford ◽  
Adrienne J. Grant ◽  
...  
Keyword(s):  
Chinese Hamster Ovary ◽  
Chinese Hamster Ovary Cells ◽  
Chinese Hamster ◽  
Drug Resistant ◽  
Wild Type ◽  
Ovary Cells

Review of the current methods of Chinese Hamster Ovary (CHO) cells cultivation for production of therapeutic protein

2020 ◽  
Vol 17 ◽  
Author(s):  
Shazid Md. Sharker ◽  
Md. Atiqur Rahman
Keyword(s):  
Chinese Hamster Ovary ◽  
Cho Cells ◽  
Mass Production ◽  
Chinese Hamster Ovary Cells ◽  
Chinese Hamster ◽  
Therapeutic Protein ◽  
Specific Productivity ◽  
Ovary Cells ◽  
Further Development ◽  
Interesting Area

Most of clinical approved protein-based drugs or under in clinical trial have a profound impact in the treatment of critical diseases. The mammalian eukaryotic cells culture approaches, particularly the CHO (Chinese Hamster Ovary) cells are mainly used in the biopharmaceutical industry for the mass-production of therapeutic protein. Recent advances in CHO cell bioprocessing to yield recombinant proteins and monoclonal antibodies have enabled the expression of quality protein. The developments of cell lines are possible to upgrade specific productivity. As a result, it holds an interesting area for academic as well as industrial researchers around the world. This review will concentrate on the recent progress of the mammalian CHO cells culture technology and the future scope of further development for the mass-production of protein therapeutics.

scholarly journals A pooled CRISPR/AsCpf1 screen using paired gRNAs to induce genomic deletions in Chinese hamster ovary cells

2021 ◽  
pp. e00649
Author(s):  
Valerie Schmieder ◽  
Neža Novak ◽  
Heena Dhiman ◽  
Ly Ngoc Nguyen ◽  
Evgenija Serafimova ◽  
...  
Keyword(s):  
Chinese Hamster Ovary ◽  
Chinese Hamster Ovary Cells ◽  
Chinese Hamster ◽  
Ovary Cells ◽  
Genomic Deletions
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