Prolyl Isomerase Pin1 Promotes Amyloid Precursor Protein (APP) Turnover by Inhibiting Glycogen Synthase Kinase-3β (GSK3β) Activity

Suk Ling Ma; Lucia Pastorino; Xiao Zhen Zhou; Kun Ping Lu

doi:10.1074/jbc.c111.298596

Prolyl Isomerase Pin1 Promotes Amyloid Precursor Protein (APP) Turnover by Inhibiting Glycogen Synthase Kinase-3β (GSK3β) Activity

Journal of Biological Chemistry ◽

10.1074/jbc.c111.298596 ◽

2011 ◽

Vol 287 (10) ◽

pp. 6969-6973 ◽

Cited By ~ 53

Author(s):

Suk Ling Ma ◽

Lucia Pastorino ◽

Xiao Zhen Zhou ◽

Kun Ping Lu

Keyword(s):

Amyloid Precursor Protein ◽

Glycogen Synthase ◽

Precursor Protein ◽

Glycogen Synthase Kinase ◽

Glycogen Synthase Kinase 3Β ◽

Prolyl Isomerase

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In Vitro Phosphorylation of the Cytoplasmic Domain of the Amyloid Precursor Protein by Glycogen Synthase Kinase-3β

Journal of Neurochemistry ◽

10.1046/j.1471-4159.1996.67020699.x ◽

2002 ◽

Vol 67 (2) ◽

pp. 699-707 ◽

Cited By ~ 104

Author(s):

Andrew E. Aplin ◽

Graham M. Gibb ◽

J. Steven Jacobsen ◽

Jean-Marc Gallo ◽

Brian H. Anderton

Keyword(s):

Amyloid Precursor Protein ◽

Glycogen Synthase ◽

Cytoplasmic Domain ◽

Precursor Protein ◽

Glycogen Synthase Kinase ◽

Glycogen Synthase Kinase 3Β

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Arylbenzofurans from the Root Bark of Morus alba as Triple Inhibitors of Cholinesterase, β-Site Amyloid Precursor Protein Cleaving Enzyme 1, and Glycogen Synthase Kinase-3β: Relevance to Alzheimer’s Disease

ACS Omega ◽

10.1021/acsomega.9b00198 ◽

2019 ◽

Vol 4 (4) ◽

pp. 6283-6294 ◽

Cited By ~ 8

Author(s):

Pradeep Paudel ◽

Su Hui Seong ◽

Yajuan Zhou ◽

Manh Tuan Ha ◽

Byung Sun Min ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Amyloid Precursor Protein ◽

Glycogen Synthase ◽

Morus Alba ◽

Precursor Protein ◽

Glycogen Synthase Kinase ◽

Root Bark ◽

Glycogen Synthase Kinase 3Β

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Insulin Suppresses the Expression of Amyloid Precursor Protein, Presenilins, and Glycogen Synthase Kinase-3β in Peripheral Blood Mononuclear Cells

The Journal of Clinical Endocrinology & Metabolism ◽

10.1210/jc.2010-2961 ◽

2011 ◽

Vol 96 (6) ◽

pp. 1783-1788 ◽

Cited By ~ 12

Author(s):

Paresh Dandona ◽

Islam Mohamed ◽

Husam Ghanim ◽

Chang Ling Sia ◽

Sandeep Dhindsa ◽

...

Keyword(s):

Amyloid Precursor Protein ◽

Peripheral Blood Mononuclear Cells ◽

Peripheral Blood ◽

Mononuclear Cells ◽

Glycogen Synthase ◽

Precursor Protein ◽

Glycogen Synthase Kinase ◽

Glycogen Synthase Kinase 3Β ◽

Peripheral Blood Mononuclear ◽

Blood Mononuclear Cells

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C‐terminal fragments of amyloid precursor protein exert neurotoxicity by inducing glycogen synthase kinase‐3β expression

The FASEB Journal ◽

10.1096/fj.03-0106fje ◽

2003 ◽

Vol 17 (13) ◽

pp. 1-28 ◽

Cited By ~ 170

Author(s):

Hye-Sun Kim ◽

Eun-Mee Kim ◽

Jean-Pyo Lee ◽

Cheol Hyoung Park ◽

Seonghan Kim ◽

...

Keyword(s):

Amyloid Precursor Protein ◽

Glycogen Synthase ◽

Precursor Protein ◽

Glycogen Synthase Kinase ◽

Glycogen Synthase Kinase 3Β

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Neuroprotective Effects of Regulators of the Glycogen Synthase Kinase-3 Signaling Pathway in a Transgenic Model of Alzheimer's Disease Are Associated with Reduced Amyloid Precursor Protein Phosphorylation

Journal of Neuroscience ◽

10.1523/jneurosci.4321-06.2007 ◽

2007 ◽

Vol 27 (8) ◽

pp. 1981-1991 ◽

Cited By ~ 190

Author(s):

E. Rockenstein ◽

M. Torrance ◽

A. Adame ◽

M. Mante ◽

P. Bar-on ◽

...

Keyword(s):

Amyloid Precursor Protein ◽

Protein Phosphorylation ◽

Signaling Pathway ◽

Glycogen Synthase ◽

Precursor Protein ◽

Glycogen Synthase Kinase ◽

Glycogen Synthase Kinase 3 ◽

Neuroprotective Effects ◽

Transgenic Model ◽

Model Of Alzheimer’S Disease

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Faculty Opinions recommendation of Interplay between cyclin-dependent kinase 5 and glycogen synthase kinase 3 beta mediated by neuregulin signaling leads to differential effects on tau phosphorylation and amyloid precursor protein processing.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1105273.561481 ◽

2008 ◽

Author(s):

Riqiang Yan

Keyword(s):

Amyloid Precursor Protein ◽

Glycogen Synthase ◽

Tau Phosphorylation ◽

Protein Processing ◽

Precursor Protein ◽

Glycogen Synthase Kinase ◽

Glycogen Synthase Kinase 3 ◽

Amyloid Precursor Protein Processing ◽

Cyclin Dependent Kinase ◽

Cyclin Dependent Kinase 5

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In vitro streptozotocin model for modeling Alzheimer-like changes: effect on amyloid precursor protein secretases and glycogen synthase kinase-3

Journal of Neural Transmission ◽

10.1007/s00702-014-1319-7 ◽

2014 ◽

Vol 122 (4) ◽

pp. 551-557 ◽

Cited By ~ 15

Author(s):

Konstanze Plaschke ◽

Jürgen Kopitz

Keyword(s):

Amyloid Precursor Protein ◽

Glycogen Synthase ◽

Precursor Protein ◽

Glycogen Synthase Kinase ◽

Glycogen Synthase Kinase 3

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Effect of increased glycogen synthase kinase-3 activity upon the maturation of the amyloid precursor protein in transfected cells

Neuroreport ◽

10.1097/00001756-199702100-00012 ◽

1997 ◽

Vol 8 (3) ◽

pp. 639-643 ◽

Cited By ~ 30

Author(s):

Andrew E. Aplin ◽

J Steven Jacobsen ◽

Brian H. Anderton ◽

Jean-Marc Gallo

Keyword(s):

Amyloid Precursor Protein ◽

Glycogen Synthase ◽

Precursor Protein ◽

Glycogen Synthase Kinase ◽

Glycogen Synthase Kinase 3 ◽

Transfected Cells

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Interplay between Cyclin-Dependent Kinase 5 and Glycogen Synthase Kinase 3 Mediated by Neuregulin Signaling Leads to Differential Effects on Tau Phosphorylation and Amyloid Precursor Protein Processing

Journal of Neuroscience ◽

10.1523/jneurosci.5245-07.2008 ◽

2008 ◽

Vol 28 (10) ◽

pp. 2624-2632 ◽

Cited By ~ 91

Author(s):

Y. Wen ◽

E. Planel ◽

M. Herman ◽

H. Y. Figueroa ◽

L. Wang ◽

...

Keyword(s):

Amyloid Precursor Protein ◽

Glycogen Synthase ◽

Tau Phosphorylation ◽

Protein Processing ◽

Precursor Protein ◽

Glycogen Synthase Kinase ◽

Glycogen Synthase Kinase 3 ◽

Amyloid Precursor Protein Processing ◽

Cyclin Dependent Kinase ◽

Cyclin Dependent Kinase 5

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Glycogen Synthase Kinase 3 Inhibition Promotes Lysosomal Biogenesis and Autophagic Degradation of the Amyloid- Precursor Protein

Molecular and Cellular Biology ◽

10.1128/mcb.00930-12 ◽

2012 ◽

Vol 32 (21) ◽

pp. 4410-4418 ◽

Cited By ~ 100

Author(s):

C. Parr ◽

R. Carzaniga ◽

S. M. Gentleman ◽

F. Van Leuven ◽

J. Walter ◽

...

Keyword(s):

Amyloid Precursor Protein ◽

Glycogen Synthase ◽

Precursor Protein ◽

Glycogen Synthase Kinase ◽

Glycogen Synthase Kinase 3 ◽

Autophagic Degradation

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