scholarly journals Regulation of Lysophospholipase Activity of the 85-kDa Phospholipase A2and Activation in Mouse Peritoneal Macrophages

1995 ◽  
Vol 270 (35) ◽  
pp. 20439-20446 ◽  
Author(s):  
Marianne G. S. de Carvalho ◽  
Joanna Garritano ◽  
Christina C. Leslie
1981 ◽  
Vol 197 (2) ◽  
pp. 523-526 ◽  
Author(s):  
Paul D. Wightman ◽  
Mary Ellen Dahlgren ◽  
James C. Hall ◽  
Philip Davies ◽  
Robert J. Bonney

Resident mouse peritoneal macrophages contain a phospholipase C of high activity that is specific for phosphatidylinositol. The activity has a neutral pH optimum, is Ca2+-dependent and has a maximum reaction velocity of 525nmol/h per mg of protein. Certain phenothiazines are potent inhibitors of this activity.


Sign in / Sign up

Export Citation Format

Share Document