scholarly journals Role of amino groups in formation of human lymphocyte-xenogeneic erythrocyte rosettes; a proposed mechanism for antigen recognition.

1975 ◽  
Vol 72 (2) ◽  
pp. 697-700 ◽  
Author(s):  
P. Lalezari ◽  
S. L. Nehlsen ◽  
J. Novodoff ◽  
I. Lalezari
Keyword(s):  
Human Lymphocyte ◽  
Antigen Recognition ◽  
Amino Groups

scholarly journals Role of anti-human lymphocyte culture cytotoxic antibodies in recurrent spontaneous pregnancy loss women

2011 ◽  
Vol 4 (1) ◽  
pp. 17 ◽  
Author(s):  
Shankarkumar Umapathy ◽  
Aruna Shankarkumar ◽  
Vanita Ramrakhiyani ◽  
Kanjaksha Ghosh
Keyword(s):  
Human Lymphocyte ◽  
Pregnancy Loss ◽  
Lymphocyte Culture ◽  
Cytotoxic Antibodies ◽  
Spontaneous Pregnancy

scholarly journals Role of capping in peptide synthesis

2020 ◽  
Vol 11 (4) ◽  
pp. 5225-5228
Author(s):  
Deepshikha Verma ◽  
Pillai V N R ◽  
Giriraj Tailor
Keyword(s):  
Peptide Synthesis ◽  
Solid Phase ◽  
Solid Phase Peptide Synthesis ◽  
Protecting Groups ◽  
Amino Groups ◽  
Peptide Chemistry ◽  
Fmoc Spps ◽  
Reliable Methods ◽  
Important Test

Protecting groups like Fmoc and coupling both steps are essential to monitoring the Fmoc SPPS (Solid Phase Peptide Synthesis) reaction completion. Reliable methods are used to detect the unreacted number of amino groups for monitoring these two essential reaction steps of coupling and cleavage. The ability to detect the complete coupling, incomplete coupling or failure of coupling we use many colour tests in the laboratory and based on this the Fmoc peptide chemistry allows the control of the completion of the Fmoc cleavage. The most important test used is the Kaiser test and highly recommended to monitor the coupling and cleavage steps. If the result of colour tests is positive after coupling, then the second coupling should be performed. Then again use the colour test to detect the level of coupling. If the result is still slightly positive, repeat coupling with the smaller modification of reagents such as used PyBOP instead of HOBT AND HOAT. These colour tests help in revealing the presence of unreacted amino-functional groups. Thus, we need to block these free N-terminal of amino- acids which help in avoiding the making of deletion of sequence.

THE ROLE OF MACROPHAGES IN T LYMPHOCYTE ANTIGEN RECOGNITION

1975 ◽  
pp. 539-554 ◽  
Author(s):  
A.S. Rosenthal ◽  
J.T. Blake ◽  
J.J. Ellner ◽  
D.K. Greineder ◽  
P.E. Lipsky
Keyword(s):  
T Lymphocyte ◽  
Antigen Recognition ◽  
Lymphocyte Antigen

scholarly journals Role of the Metal Surface on the Room Temperature Activation of the Alcohol and Amino Groups of p-Aminophenol

2020 ◽  
Vol 124 (36) ◽  
pp. 19655-19665
Author(s):  
Nerea Ruiz del Árbol ◽  
Irene Palacio ◽  
Carlos Sánchez-Sánchez ◽  
Gonzalo Otero-Irurueta ◽  
José I. Martínez ◽  
...  
Keyword(s):  
Metal Surface ◽  
Room Temperature ◽  
Amino Groups ◽  
Temperature Activation

scholarly journals Enhanced biosorption of Cr(VI) using cotton fibers coated with chitosan – role of ester bonds

2018 ◽  
Vol 78 (3) ◽  
pp. 476-486 ◽  
Author(s):  
Sergio I. Rojas ◽  
Diana C. Duarte ◽  
Sergio D. Mosquera ◽  
Felipe Salcedo ◽  
Juan P. Hinestroza ◽  
...  
Keyword(s):  
Hexavalent Chromium ◽  
Freundlich Isotherm ◽  
Kinetic Studies ◽  
Chitosan Solution ◽  
Cotton Fibers ◽  
Isotherm Models ◽  
Order Kinetic ◽  
Amino Groups ◽  
Removal Capacity

Abstract We report on the role of ester bonds in the enhanced removal of hexavalent chromium from water using cotton fibers coated with chitosan. Adsorption capacities up to five times higher than those of the unmodified fibers were observed when the cotton fibers were exposed to an NaOH, followed by citric acid (0.97 M), and a chitosan solution (2%). We found that the use of NaOH favors the formation of ester bonds over amide bonds on the surface of the cotton fibers. This increase in the surface density of ester bonds generates an increase in the amount of exposed amino groups from the chitosan, hence increasing the removal capacity of the modified fibers. Experimental results also reveal that the adsorption is induced by the electrostatic attraction between the protonated amino groups on the surface and the negatively charged chromium ions in the water. Adsorption isotherms and kinetic studies indicated that the adsorption process fits the Langmuir and the Freundlich isotherm models as well as the pseudo-first and pseudo-second order kinetic models. These results can open a new avenue for the manufacturing of fibers with enhanced removal capacities for hexavalent chromium.

scholarly journals The interaction of spermine and pentamines with DNA

1987 ◽  
Vol 244 (1) ◽  
pp. 243-246 ◽  
Author(s):  
H S Basu ◽  
L J Marton
Keyword(s):  
High Temperature ◽  
Melting Temperature ◽  
Conformational Changes ◽  
Thermus Thermophilus ◽  
Total Charge ◽  
Amino Groups ◽  
Carbon Chains ◽  
Naturally Occurring ◽  
Calf Thymus

We studied the effects of spermine, two naturally-occurring pentamines isolated from the thermophile Thermus thermophilus and one synthetic pentamine on the aggregation and ‘melting’ temperature of calf-thymus DNA and on the B-to-Z transition of poly(dG-me5dC). All pentamines caused aggregation of DNA at much lower concentrations than that of spermine. Concentrations that increased the melting temperature of DNA and induced the B-to-Z transition in poly(dG-me5dC) were different for each pentamine, but were comparable with the concentration of spermine needed to cause these effects. Our results suggest that both the total charge and the distance separating the charge, which is a function of the length of the carbon chains between amino groups, are important for the induction of conformational changes in DNA. The biological role of pentamines in T. thermophilus appears to be related to their ability to promote DNA condensation at high temperature.

Sign in / Sign up

Export Citation Format

Share Document