scholarly journals Increased Uptake of Amino Acids and 2-Deoxy-D-Glucose by Virus-Transformed Cells in Culture

1972 ◽  
Vol 69 (3) ◽  
pp. 585-589 ◽  
Author(s):  
K. J. Isselbacher
Keyword(s):  
Amino Acids ◽  
Transformed Cells ◽  
Cells In Culture

Stimulus-coupled release of amino acids from cerebellar granule cells in culture

1988 ◽  
Vol 448 (1) ◽  
pp. 46-52 ◽  
Author(s):  
Ann Kingsbury ◽  
Vittorio Gallo ◽  
Robert Balazs
Keyword(s):  
Amino Acids ◽  
Granule Cells ◽  
Cerebellar Granule Cells ◽  
Cerebellar Granule ◽  
Cells In Culture

scholarly journals Prognostic Significance of Serum Free Amino Acids in Head and Neck Cancers

Cells ◽  
2019 ◽  
Vol 8 (5) ◽  
pp. 428 ◽  
Author(s):  
Vit Vsiansky ◽  
Marketa Svobodova ◽  
Jaromir Gumulec ◽  
Natalia Cernei ◽  
Dagmar Sterbova ◽  
...  
Keyword(s):  
Amino Acids ◽  
Amino Acid ◽  
Regression Model ◽  
Head And Neck ◽  
Cell Lines ◽  
Proportional Hazards ◽  
Cox Proportional Hazards ◽  
Transformed Cells ◽  
Cox Proportional Hazards Regression ◽  
Proportional Hazards Regression

Despite distinctive advances in the field of head and neck squamous cell cancer (HNSCC) biomarker discovery, the spectrum of clinically useful prognostic serum biomarkers is limited. As metabolic activities in highly proliferative transformed cells are fundamentally different from those in non-transformed cells, specific shifts in concentration of different metabolites may serve as diagnostic or prognostic markers. Blood amino acids have been identified as promising biomarkers in different cancers before, but little is known about this field in HNSCC. Blood amino acid profiles of 140 HNSCC patients were examined using high-performance liquid chromatography. Cox proportional hazards regression model was used to assess the prognostic value of amino acid concentrations in serum. Colony forming assay was used to identify the effect of amino acids that were significant in Cox proportional hazards regression models on colony forming ability of FaDu and Detroit 562 cell lines. In the multivariable Cox regression model for overall survival (OS), palliative treatment was associated with an unfavourable prognosis while high serum levels of methionine have had a positive prognostic impact. In the relapse-free survival (RFS) multivariable model, methionine was similarly identified as a positive prognostic factor, along with tumor localization in the oropharynx. Oral cavity localization and primary radio(chemo)therapy treatment strategy have been linked to poorer RFS. 1mM serine was shown to support the forming of colonies in both tested HNSCC cell lines. Effect of methionine was exactly the opposite.

Selective Inhibition of Transformed Cells in Culture by Anti-thymidine Antibodies

1971 ◽  
Vol 234 (47) ◽  
pp. 127-128 ◽  
Author(s):  
D. S. P. LIEBESKIND ◽  
K. C. HSU ◽  
B. F. ERLANGER ◽  
S. M. BEISER
Keyword(s):  
Selective Inhibition ◽  
Transformed Cells ◽  
Cells In Culture

Determination of the h-protein in transformable and transformed cells in culture

Biochemistry ◽  
1972 ◽  
Vol 11 (11) ◽  
pp. 2116-2124 ◽  
Author(s):  
Toshio Kuroki ◽  
Charles Heidelberger
Keyword(s):  
Transformed Cells ◽  
Cells In Culture ◽  
H Protein

Permeabilization of transformed cells in culture by external ATP

1985 ◽  
Vol 86 (3) ◽  
pp. 189-196 ◽  
Author(s):  
Leon A. Heppel ◽  
Gary A. Weisman ◽  
Ilan Friedberg
Keyword(s):  
Transformed Cells ◽  
Cells In Culture

MSA and EGF receptors on saroma virus transformed cells and human fibrosarcoma cells in culture

Nature ◽  
1977 ◽  
Vol 267 (5611) ◽  
pp. 526-528 ◽  
Author(s):  
GEORGE J. TODARO ◽  
JOSEPH E. DE LARCO ◽  
S. PETER NISSLEY ◽  
MATTHEW M. RECHLER
Keyword(s):  
Transformed Cells ◽  
Egf Receptors ◽  
Cells In Culture ◽  
Fibrosarcoma Cells ◽  
Human Fibrosarcoma Cells

Advantages of the scanning ion microscopy for mapping halogen corticoids in normal and transformed cells in culture

1994 ◽  
Vol 81 (1) ◽  
pp. 65-72 ◽  
Author(s):  
Jean-Pierre Berry ◽  
Marcel Chaintreau ◽  
Danièle Chassoux ◽  
Robert Dennebouy ◽  
Françoise Escaig ◽  
...  
Keyword(s):  
Transformed Cells ◽  
Cells In Culture ◽  
Ion Microscopy
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