scholarly journals Structural origins for the product specificity of SET domain protein methyltransferases

2008 ◽  
Vol 105 (52) ◽  
pp. 20659-20664 ◽  
Author(s):  
J.-F. Couture ◽  
L. M. A. Dirk ◽  
J. S. Brunzelle ◽  
R. L. Houtz ◽  
R. C. Trievel
Keyword(s):  
Set Domain ◽  
Product Specificity ◽  
Domain Protein ◽  
Protein Methyltransferases

Exploring the origin of the catalytic power and product specificity of SET domain protein methyltransferase

2016 ◽  
Vol 12 (10) ◽  
pp. 2980-2983 ◽  
Author(s):  
A. H. Lima ◽  
C. N. Alves ◽  
R. Prasad ◽  
J. Lameira
Keyword(s):  
Computer Simulation ◽  
Set Domain ◽  
Product Specificity ◽  
Protein Methyltransferase ◽  
Domain Protein ◽  
Catalytic Power

Computer simulation reveals that the origin of SET8 catalytic power is mainly due to electrostatic preorganization.

scholarly journals Strategy to Target the Substrate Binding site of SET Domain Protein Methyltransferases

2013 ◽  
Vol 53 (3) ◽  
pp. 681-691 ◽  
Author(s):  
Kong T. Nguyen ◽  
Fengling Li ◽  
Gennadiy Poda ◽  
David Smil ◽  
Masoud Vedadi ◽  
...  
Keyword(s):  
Binding Site ◽  
Substrate Binding ◽  
Set Domain ◽  
Substrate Binding Site ◽  
Domain Protein ◽  
Protein Methyltransferases

Kinetic Manifestation of Processivity during Multiple Methylations Catalyzed by SET Domain Protein Methyltransferases†

Biochemistry ◽  
2007 ◽  
Vol 46 (12) ◽  
pp. 3905-3915 ◽  
Author(s):  
Lynnette M. A. Dirk ◽  
E. Megan Flynn ◽  
Kevin Dietzel ◽  
Jean-François Couture ◽  
Raymond C. Trievel ◽  
...  
Keyword(s):  
Set Domain ◽  
Domain Protein ◽  
Protein Methyltransferases

scholarly journals The SET domain protein Metnase mediates foreign DNA integration and links integration to nonhomologous end-joining repair

2005 ◽  
Vol 102 (50) ◽  
pp. 18075-18080 ◽  
Author(s):  
S.-H. Lee ◽  
M. Oshige ◽  
S. T. Durant ◽  
K. K. Rasila ◽  
E. A. Williamson ◽  
...  
Keyword(s):  
Nonhomologous End Joining ◽  
Set Domain ◽  
End Joining ◽  
Dna Integration ◽  
Foreign Dna ◽  
Domain Protein ◽  
Foreign Dna Integration
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