scholarly journals Danna and Nathans: Restriction enzymes and the boon to modern molecular biology

2005 ◽  
Vol 102 (17) ◽  
pp. 5909-5909 ◽  
Author(s):  
C. Brownlee
Keyword(s):  
Molecular Biology ◽  
Restriction Enzymes ◽  
Modern Molecular Biology

scholarly journals Mining for Restriction Endonucleases in Nicaragua

Encuentro ◽  
2012 ◽  
pp. 49-62
Author(s):  
Suyén E. Espinoza-Miranda ◽  
Julio A. Gómez-Rodríguez ◽  
Jorge Huete-Pérez
Keyword(s):  
Molecular Biology ◽  
Central America ◽  
Restriction Enzymes ◽  
Research Capacity ◽  
Central American ◽  
Industrial Enzymes ◽  
Biotechnology Research ◽  
Rdna Sequencing ◽  
Modern Molecular Biology ◽  
The University

The Molecular Biology Center at the University of Central America in Nicaragua(CBM-UCA) was founded in 1999 to strengthen biotechnology research capacity and education in Nicaragua and the Central American region. One of the first projects launched by the CBM-UCA was bio-prospecting for key industrial enzymes. This ongoing study seeks to discover and characterize restriction enzymes (RE) in bacteria, and to create a database of microorganisms isolated and identified by 16S rDNA sequencing methodology. In this paper we highlight the importance of studying the extreme environmental conditions for building knowledge of Nicaraguan biodiversity through modern molecular biology techniques such as metagenomics. The isolation of prototype enzymes such as EcoRV and ClaI is presented as an update and extension of previously undertaken work.

Modern Molecular Biology Technologies and Higher Usability of Ancient Knowledge of Medicinal Plants for Treatment of Human Diseases

2019 ◽  
pp. 173-205 ◽  
Author(s):  
Venkatesh Vaidyanathan ◽  
Vijay Naidu ◽  
Anower Jabed ◽  
Khanh Tran ◽  
Prasanna Kallingappa ◽  
...  
Keyword(s):  
Medicinal Plants ◽  
Molecular Biology ◽  
Human Diseases ◽  
Modern Molecular Biology

Phenytoin-Induced Pseudolymphoma: Reevaluation Using Modern Molecular Biology Techniques

Epilepsia ◽  
1996 ◽  
Vol 37 (1) ◽  
pp. 104-107 ◽  
Author(s):  
Yung-Ming Jeng ◽  
Hwei-Fan Tien ◽  
Ih-Jen Su
Keyword(s):  
Molecular Biology ◽  
Modern Molecular Biology

scholarly journals T cell traffic signals

2005 ◽  
Vol 202 (4) ◽  
pp. 460-460
Author(s):  
Heather L. Van Epps
Keyword(s):  
T Cells ◽  
T Cell ◽  
Molecular Biology ◽  
Memory T Cells ◽  
Traffic Signals ◽  
Lymphocyte Homing ◽  
Modern Molecular Biology ◽  
Migratory Routes

In 1990, Charles Mackay and colleagues combined classical physiology with modern molecular biology to provide the first concrete evidence that naive and memory T cells follow distinct migratory routes out of the bloodstream— a discovery that helped invigorate the field of lymphocyte homing.

scholarly journals Anniversary of the Theory of Academician E.N. Pavlovsky about the Natural Focality of Diseases (1939 - 2014)

2015 ◽  
Vol 14 (1) ◽  
pp. 9-16 ◽  
Author(s):  
E. I. Korenberg
Keyword(s):  
Molecular Biology ◽  
75Th Anniversary ◽  
Modern Molecular Biology ◽  
Natural Foci ◽  
Ecological Methods ◽  
Traditional Population

In connection with the 75th anniversary of the theory of academician E.N. Pavlovsky about the natural focality of diseases presents the General results of the development of its fundamental theoretical positions. Planned most promising areas for further research, which can immeasurably increase when the combination of modern molecular biology and traditional population-ecological methods for the study of natural foci.

scholarly journals RNA-Targeting CRISPR–Cas Systems and Their Applications

2020 ◽  
Vol 21 (3) ◽  
pp. 1122 ◽  
Author(s):  
Michal Burmistrz ◽  
Kamil Krakowski ◽  
Agata Krawczyk-Balska
Keyword(s):  
Molecular Biology ◽  
Current Knowledge ◽  
Type Ii ◽  
Rna Molecules ◽  
Dna Targeting ◽  
Modern Molecular Biology ◽  
Rna Targeting ◽  
New Research ◽  
Target Rna ◽  
Research Tools

Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)–CRISPR-associated (Cas) systems have revolutionized modern molecular biology. Numerous types of these systems have been discovered to date. Many CRISPR–Cas systems have been used as a backbone for the development of potent research tools, with Cas9 being the most widespread. While most of the utilized systems are DNA-targeting, recently more and more attention is being gained by those that target RNA. Their ability to specifically recognize a given RNA sequence in an easily programmable way makes them ideal candidates for developing new research tools. In this review we summarize current knowledge on CRISPR–Cas systems which have been shown to target RNA molecules, that is type III (Csm/Cmr), type VI (Cas13), and type II (Cas9). We also present a list of available technologies based on these systems.

Who Pooped and How It Was Found

2017 ◽  
Author(s):  
Tricia Coakley
Keyword(s):  
Molecular Biology ◽  
Real World ◽  
Cost Effective ◽  
Fecal Pollution ◽  
Important Task ◽  
Source Tracking ◽  
Fecal Bacteria ◽  
Non Profit ◽  
Pollution Problem ◽  
Modern Molecular Biology

Tracking the sources of fecal pollution in Kentucky streams is an important task to allow for removal of the associated pollution. Modern molecular biology techniques, analyzing the DNA of fecal bacteria, provide cost effective methods and make fecal source tracking possible for municipalities and non-profit organizations. This is a story of the use of these methods by a collaboration of stakeholders to solve a real world fecal pollution problem in Lexington, Kentucky.

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