Effects of Fasting and Sedation on Gastrointestinal-Tract Function in 2 Potoroine Marsupials

1988 ◽  
Vol 36 (4) ◽  
pp. 411 ◽  
Author(s):  
ID Hume ◽  
CH Carlisle ◽  
K Reynolds ◽  
MA Pass
Keyword(s):  
Small Intestine ◽  
Gastrointestinal Tract ◽  
Contrast Medium ◽  
Barium Sulfate ◽  
Primary Role ◽  
Daily Cycle ◽  
Secondary Importance ◽  
Ketamine Hydrochloride ◽  
Tract Function ◽  
Potorous Tridactylus

Radiographic techniques were used to follow the movement of barium sulfate given orally, either as a suspension or incorporated into feed pellets, through the gastrointestinal tract of two potoroine marsupials, Aepyprymnus rufescens, the rufous rat-kangaroo; and Potorous tridactylus, the long-nosed potoroo. Compared with previously reported results from fed animals, fasting for 12-15 h delayed the passage of contrast medium into the small intestine, but sedation with ketamine hydrochloride visibly increased gastrointestinal tract activity and significantly reduced retention times of contrast medium in the stomach. A daily cycle of ingesta movements within the potoroine stomach, consequent upon the discontinuous feeding pattern and nature of the diet of these small marsupials, is proposed. In this proposal the sacciform region of the forestomach plays a primary role in storage of ingesta for later digestion in the intestine, and fermentative digestion of fibre is of secondary importance.

A Radiographic Study of the Gastrointestinal-Tract of Potorous-Tridactylus, With a Suggestion as to the Role of the Foregut and Hindgut in Potoroine Marsupials

1986 ◽  
Vol 34 (4) ◽  
pp. 463 ◽  
Author(s):  
PB Frappell ◽  
RW Rose
Keyword(s):  
Gastrointestinal Tract ◽  
Contrast Medium ◽  
Barium Sulphate ◽  
Proximal Colon ◽  
Radiographic Study ◽  
Colon And Rectum ◽  
Descending Colon ◽  
New Interpretation ◽  
Potorous Tridactylus

The gastric distribution of barium sulphate and its subsequent intestinal passage were examined by radiography in Potorous tridactylus. Barium sulphate administered in association with solid food passed to the sacciform forestomach from the tubiform forestomach. However, ingested barium sulphate suspension mainly entered the hindstomach via the gastric sulcus. Barium sulphate which entered the sacciform forestomach remained for no more than 1 h before passing to the hindstomach via the tubiform forestomach. The passage of contrast medium through the intestine was followed in adults administered barium sulphate suspension only. Contrast medium which entered the hindstomach was not detectable there after 10 min. Barium sulphate first arrived at the caecum and proximal colon after 20 min, and by 45 min the majority had reached these organs. It persisted in the caecum and proximal colon for several hours, during which there was some movement into the descending colon and rectum. These results lead towards a new interpretation of the role of the potoroine foregut and hindgut.

Radiographic Studies on the Structure and Function of the Gastrointestinal Tract of Two Species of Potoroine Marsupials.

1985 ◽  
Vol 33 (5) ◽  
pp. 641 ◽  
Author(s):  
ID Hume ◽  
CH Carlisle
Keyword(s):  
Gastrointestinal Tract ◽  
Contrast Medium ◽  
Barium Sulphate ◽  
Structure And Function ◽  
And Function ◽  
Potorous Tridactylus

The structure and function of the gastrointestinal tracts of 2 potoroine marsupials, Aepyprymnus rufescens, the rufous rat-kangaroo, and Potorous tridactylus, the long-nosed potoroo, were examined by the use of radiographic and fluoroscopic techniques. In both species barium sulphate given by mouth entered the sacciform forestomach within 20 min of dosing, but in the same time the hindstomach and duodenum were clearly outlined. Contrast medium reached the hindgut within 1 to 2 h, but was retained there for at least 24 h. A proportion of radio-opaque particles given by mouth also bypassed the sacciform forestomach, but those that entered the gastric region were retained there for up to 93 h. The stomach constituted 50% of total gut capacity, and the hindgut (caecum and colon) 35%. The sacciform forestomach was the largest gastric region. It is concluded that, on the basis of anatomy and digesta movements, the forestomach may be less important, and the hindgut more important, in fermentative digestion in the Potoroinae than in the Macropodidae.

scholarly journals Expression of proposed methionine transporters along the gastrointestinal tract of pigs and their regulation by dietary methionine sources

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Stella Romanet ◽  
Jörg R. Aschenbach ◽  
Robert Pieper ◽  
Jürgen Zentek ◽  
John K. Htoo ◽  
...  
Keyword(s):  
Small Intestine ◽  
Gastrointestinal Tract ◽  
Protein Expression ◽  
Mrna Expression ◽  
Oral Mucosa ◽  
Protein Translation ◽  
Primary Role ◽  
Intestinal Segments ◽  
Small Intestinal

Abstract Background Given the key role of methionine (Met) in biological processes like protein translation, methylation, and antioxidant defense, inadequate Met supply can limit performance. This study investigated the effect of different dietary Met sources on the expression profile of various Met transporters along the gastrointestinal tract (GIT) of pigs. Methods A total of 27 pigs received a diet supplemented with 0.21% DL-Met, 0.21% L-Met, or 0.31% DL-2-hydroxy-4-(methylthio)butanoic acid (DL-HMTBA). Changes in mRNA expression of B0AT1, ATB0,+, rBAT, ASCT2, IMINO, LAT4, y+LAT1, LAT2, and SNAT2 were evaluated in the oral mucosa, cardia, fundus, pylorus, duodenum, proximal jejunum, middle jejunum, ileum, cecum, proximal colon, and distal colon, complemented by protein expression analysis of B0AT1, ASCT2, LAT2, and LAT4. Results Expression of all investigated transcripts differed significantly along the GIT. B0AT1, rBAT, y+LAT1, LAT2, and LAT4 showed strongest mRNA expression in small intestinal segments. ASCT2, IMINO, and SNAT2 were similarly expressed along the small and large intestines but expression differed in the oral mucosa and stomach. ATB0,+ showed highest mRNA expression in large intestinal tissues, cardia, and pylorus. In pigs fed DL-Met, mRNA expression of ASCT2 was higher than in pigs fed DL-HMTBA in small intestinal tissues and mRNA expression of IMINO was lower than in pigs fed L-Met in large intestinal tissues. Dietary DL-HMTBA induced a stronger mRNA expression of basolateral uptake systems either in the small (LAT2) or large (y+LAT1) intestine. Protein expression of B0AT1 was higher in the middle jejunum and ileum in pigs fed DL-Met when compared with the other Met supplements. LAT4 expression was higher in pigs fed DL-HMTBA when compared with DL-Met (small intestine) and L-Met (small intestine, oral mucosa, and stomach). Conclusion A high expression of several Met transporters in small intestinal segments underlines the primary role of these segments in amino acid absorption; however, some Met transporters show high transcript and protein levels also in large intestine, oral mucosa, and stomach. A diet containing DL-Met has potential to increase apical Met transport in the small intestine, whereas a diet containing DL-HMTBA has potential to increase basolateral Met transport in the small intestine and, partly, other gastrointestinal tissues.

scholarly journals Anatomic-radiographic aspects and gastrointestinal transit time in boa constrictor amarali stull, 1932 (Squamata, Boidae)

2020 ◽  
Vol 72 (6) ◽  
pp. 2201-2210
Author(s):  
V.M.F. Milken ◽  
M.L.C. Soares ◽  
N.B. Martins ◽  
A.L.Q. Santos
Keyword(s):  
Small Intestine ◽  
Contrast Medium ◽  
Transit Time ◽  
Barium Sulfate ◽  
Gastrointestinal Transit ◽  
Gastrointestinal Transit Time ◽  
Boa Constrictor ◽  
Filling Time ◽  
The Mean ◽  
Emptying Time

ABSTRACT The goal of this study was to describe the gastrointestinal transit technique in the Boa constrictor amarali. For that purpose, we obtained simple radiographic images of seven serpents, subsequently administering a 25mL/kg dose of barium sulfate and establishing a radiographic sequence at the following times: 5 minutes; 1, 2, 3, 6, 9, 24, 48, 72 and 96 hours, extending to 120 and 126 hours for one animal. The mean esophageal transit was 26.71±19.48 hours; the mean gastric filling time was 28.57±27.22 minutes and the emptying time was 60±12 hours; the mean filling time of the contrast medium in the small intestine was 3±2.16 hours and the emptying time was 97±15.65 hours. We also obtained the mean filling time of the large intestine, which was 40±11.31 hours. We found that the mean passage time of the contrast medium through the cranial gastrointestinal tract - until the complete elimination of barium sulfate from the small intestine -was 97±15.65 hours. In addition to determining the gastrointestinal transit time, the technique used allowed for the morphological identification of the alimentary canal.

CHANGES IN SMALL INTESTINE MICROFLORA IN PATIENTS WITH ACUTE INTESTINAL OBSTRUCTION

2020 ◽  
pp. 16-18
Author(s):  
V. M. Lykhman ◽  
O. M. Shevchenko ◽  
Ye. O. Bilodid ◽  
Igor Vladimirovich Volchenko ◽  
I. A. Kulyk ◽  
...  
Keyword(s):  
Small Intestine ◽  
Gastrointestinal Tract ◽  
Species Composition ◽  
Intestinal Obstruction ◽  
Bacterial Flora ◽  
Anaerobic Bacteria ◽  
Acute Intestinal Obstruction ◽  
Gram Positive ◽  
Mechanical Intestinal Obstruction ◽  
Facultative Anaerobic Bacteria

Among urgent surgical diseases of abdominal cavity, an acute intestinal obstruction is the most difficult to be diagnosed and treated. Leading factor, determining the development of pathophysiological processes is considered to be the progressive manifestations of enteric insufficiency syndrome, resulting in intestinal barrier impairment, negative changes in ecology of intestinal flora, increased endotoxins. To identify the small intestine microflora in acute intestinal obstruction and determine the role of dysbiotic disorders in clinical manifestations of main pathological process, a study was conducted in 60 patients with mechanical intestinal obstruction. The small intestine has a relatively rare microflora, consisting mainly of gram−positive facultative aerobic microorganisms, streptococci, lactobacilli. The distal ileum in nearly 30−55 % of healthy people contains scanty microflora, and yet the flora of this area differs from the microbial population of the higher gastrointestinal tract due to higher concentration of gram−negative bacteria. Optional−anaerobic coliform bacilli, anaerobic bifidobacteria and fusobacteria, bacteroids, the number of which starts exceeding the one of gram−positive species, are presented in significant quantities. Distal to the ileocecal valve there are significant changes in the microflora quantitative and species composition. Obligatory anaerobic bacteria become the predominant part of microflora, exceeding the number of aerobic and facultative anaerobic bacteria. The bacterial flora in different parts of gastrointestinal tract has its own specifics and is quite constant, as a result of the interaction of many factors, regulating the bacterial population in small intestine. The most important among them are: acidity of gastric juice, normal peristaltic activity of the intestine, bacterial interactions and immune mechanisms. Disorders of the intestine motor and evacuation function with its obstruction lead to slow passage of the chyme and contamination of the upper gastrointestinal tract with new types of microbes. There is a syndrome of small intestine excessive colonization, which means an increased concentration of bacterial populations in it, similar in species composition to the colon microflora. Pathological intra−intestinal contents become a source of endogenous infection and re−infection of the patient, leads to internal digestive disorders, which is manifested by syndrome of malabsorption of proteins, carbohydrates and vitamins. Key words: acute intestinal obstruction, small intestinal microflora, conditionally pathogenic microorganisms, intestinal biocenosis.

scholarly journals A long-term survivor of clear cell sarcoma-like tumor of the gastrointestinal tract with liver metastasis: a case report

2020 ◽  
Vol 6 (1) ◽  
Author(s):  
Takuhisa Okada ◽  
Yasumitsu Hirano ◽  
Shintaro Ishikawa ◽  
Hiroka Kondo ◽  
Toshimasa Ishii ◽  
...  
Keyword(s):  
Small Intestine ◽  
Lymph Node ◽  
Gastrointestinal Tract ◽  
Liver Metastasis ◽  
Surgical Resection ◽  
Clear Cell ◽  
Clear Cell Sarcoma ◽  
Cell Sarcoma

Abstract Background Clear cell sarcoma-like tumor of the gastrointestinal tract (CCSLTGT) is extremely rare. It is a mesenchymal neoplasm that usually forms in the small intestine of adolescents and young adults, is prone to local recurrence and metastasis, and has a high mortality rate. We report a patient with CCSLTGT with lymph node- and liver metastases, who continues to survive 6 years after initial surgical resection. Case presentation A 38-year-old woman presented with lightheadedness. Laboratory analysis revealed anemia (hemoglobin, 6.7 g/dL), and enhanced computed tomography (CT) demonstrated a mass in the small intestine, about 6 cm in diameter, with swelling of 2 regional lymph nodes. Double-balloon small intestine endoscopic examination revealed a tumor accompanied by an ulcer; the biopsy findings suggested a primary cancer of the small intestine. She was admitted, and we then performed a laparotomy for partial resection of the small intestine with lymph node dissection. Pathologic examination revealed CCSLTGT with regional lymph node metastases. About 3 years later, follow-up CT revealed a single liver metastasis. Consequently, she underwent a laparoscopic partial liver resection. Histopathologic examination confirmed that the liver metastasis was consistent with CCSLTGT. It has now been 3 years without a recurrence. Conclusion Repeated radical surgical resection with close follow-up may be the only way to achieve long-term survival in patients with CCLSTGT.

Evaluation of a dual-purpose contrast medium for radiography and ultrasonography of the small intestine in dogs

2020 ◽  
Vol 81 (12) ◽  
pp. 950-957
Author(s):  
Jiwon Kang ◽  
Donghyun Oh ◽  
Jeongwoo Choi ◽  
Kyeonga Kim ◽  
Junghee Yoon ◽  
...  
Keyword(s):  
Small Intestine ◽  
Contrast Medium ◽  
Dual Purpose
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