The development, structure, and function of the submandibular cutaneous (chin) glands in the rabbit.

1964 ◽  
Vol 12 (3) ◽  
pp. 340 ◽  
Author(s):  
AG Lyne ◽  
GS Molyneux ◽  
R Mykytowycz ◽  
PF Parakkal

Embryological, histological, and histochemical features of the chin glands in the rabbit, Oryctolagus cuniculus (L.), are described. The glands are modified sweat glands which develop as appendages of the first hair follicles of the pelage. All the secretory cells are of the merocrine type, although some secrete in the typical apocrine manner. In the adult, the glands are much better developed in males than in females. Two main types of secretory cells were clearly seen in most animals, particularly adult males. Cells which stained heavily with osmium tetroxide (dark cells) were also present. No other mammalian cutaneous gland is so complex. Histochemical techniques to demonstrate enzymes revealed that particular glandular components contained large amounts of alkaline phosphatase and the whole gland was well supplied with nerves containing cholinesterases. The function of the secretion from these glands in marking territories is outlined.

2020 ◽  
pp. 3-14

The structure and function of the skin details the individual components of the epidermis, dermis, and their roles in normal skin health. The individual cell types in the epidermis, the different epidermal layers, and the roles of the keratinocyte are explained. The epidermis and dermis, and their important relation to each other through the dermoepidermal junction are described. The dermal adnexal structures of hair follicles (pilosebaceous units), sweat glands, and nerves are all considered. The functions of skin and barrier function are also listed. Rare but important causes of disordered sweating (hyperhidrosis and hypohidrosis) are described. In addition, presentations of hyperhidrosis are discussed.


Author(s):  
Yao Lin ◽  
Liyun Chen ◽  
Mingjun Zhang ◽  
Sitian Xie ◽  
Lijie Du ◽  
...  

Eccrine sweat glands (ESGs) play an important role in temperature regulation by secreting sweat. Insufficiency or dysfunction of ESGs in a hot environment or during exercise can lead to hyperthermia, heat exhaustion, heatstroke, and even death, but the ability of ESGs to repair and regenerate themselves is very weak and limited. Repairing the damaged ESGs and regenerating the lost or dysfunctional ESGs poses a challenge for dermatologists and bum surgeons. To promote and accelerate research on the repair and regeneration of ESGs, we summarized the development, structure and function of ESGs, and current strategies to repair and regenerate ESGs based on stem cells, scaffolds, and possible signaling pathways involved.


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