Skin morphology in fossil and living dipnoans

2020 ◽  
Author(s):  
Anne Kemp
Keyword(s):  
Skin Morphology

Determination of skin morphology and related factors in menopause rats

2021 ◽  
Vol 172 (9) ◽  
pp. 376-379
Author(s):  
M. S. Ji ◽  
◽  
X. Y. Yang ◽  
Y. Hao ◽  
J. Shi ◽  
...  
Keyword(s):  
Related Factors ◽  
Skin Morphology

scholarly journals Specificities of the Skin Morphology in Juvenile Minipigs

2018 ◽  
Vol 46 (7) ◽  
pp. 821-834 ◽  
Author(s):  
Béatrice E. Gauthier ◽  
Laure Penard ◽  
Nicole F. Bordier ◽  
Jean-Paul J. Briffaux ◽  
Bernard M. Ruty
Keyword(s):  
Skin Morphology

scholarly journals PPAR-Gamma Agonist Pioglitazone Reduced CD68+ but Not CD163+ Macrophage Dermal Infiltration in Obese Psoriatic Patients

PPAR Research ◽  
2020 ◽  
Vol 2020 ◽  
pp. 1-6 ◽  
Author(s):  
Ya. O. Yemchenko ◽  
V. I. Shynkevych ◽  
K. Ye Ishcheikin ◽  
I. P. Kaidashev
Keyword(s):  
Immunohistochemical Study ◽  
Ppar Gamma ◽  
Obese Patients ◽  
Before And After ◽  
Anti Inflammatory ◽  
Inflammatory Profile ◽  
Skin Morphology ◽  
Macrophage Populations ◽  
Inflammatory Action ◽  
M1 And M2 Macrophages

Background. Macrophages are of great importance in the development of obesity and psoriasis. Signaling via PPAR-γ in certain macrophage populations is associated with M2-like features and anti-inflammatory profile. In this research, we evaluated the anti-inflammatory action of pioglitazone by the immunohistochemical study of M1 and M2 macrophages in psoriasis-affected skin in obese patients. Methods. We used immunohistochemistry to characterize CD68+ and CD163+ macrophages and pathomorphological description of skin biopsy, obtained from 6 obese psoriatic patients before and after treatment with 15, 30, and 45 mg pioglitazone, once a day during 6 months. Two patients with conventional therapy and without pioglitazone served as control. Results. Generally, CD163+ cell quantities in psoriasis-affected skin significantly dominated over CD68+ before and after all treatment regiments. Among patients who received pioglitazone, some of them clearly responded to treatment from lowest to highest doses by decreasing CD68+ cells. In the group with 30 mg pioglitazone regiment, we detected a significant reduction of CD68+ cells in dermal infiltrates: CI 95% (16–32) before versus CI 95% (2–7) after treatment. Pioglitazone dose escalation led to certain normalization of skin morphology. Conclusion. The immunohistochemical study allows us to show the anti-inflammatory effect of pioglitazone in psoriatic obese patients, which can be mediated by reducing the number of СD68+ macrophages, but not СD163+ macrophages, in the affected dermis.

scholarly journals Comparison of optical coherence tomography and high frequency ultrasound imaging in mice for the assessment of skin morphology and intradermal volumes

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Kornelia Schuetzenberger ◽  
Martin Pfister ◽  
Alina Messner ◽  
Vanessa Froehlich ◽  
Gerhard Garhoefer ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
High Frequency ◽  
Ex Vivo ◽  
Clinical Settings ◽  
Optical Coherence ◽  
High Frequency Ultrasound ◽  
Skin Morphology ◽  
Frequency Ultrasound ◽  
Good Agreement

Abstract Optical coherence tomography (OCT) and high-frequency ultrasound (HFUS), two established imaging modalities in the field of dermatology, were evaluated and compared regarding their applicability for visualization of skin tissue morphology and quantification of murine intradermal structures. The accuracy and reproducibility of both methods were assessed ex vivo and in vivo using a standardized model for intradermal volumes based on injected soft tissue fillers. OCT revealed greater detail in skin morphology, allowing for detection of single layers due to the superior resolution. Volumetric data measured by OCT (7.9 ± 0.3 μl) and HFUS (7.7 ± 0.5 μl) were in good agreement and revealed a high accuracy when compared to the injected volume of 7.98 ± 0.8 µl. In vivo, OCT provided a higher precision (relative SD: 26% OCT vs. 42% HFUS) for the quantification of intradermal structures, whereas HFUS offered increased penetration depth enabling the visualization of deeper structures. A combination of both imaging technologies might be valuable for tumor assessments or other dermal pathologies in clinical settings.

scholarly journals Phylogenetic investigation of skin sloughing rates in frogs: relationships with skin characteristics and disease-driven declines

2019 ◽  
Vol 286 (1896) ◽  
pp. 20182378 ◽  
Author(s):  
Michel E. B. Ohmer ◽  
Rebecca L. Cramp ◽  
Craig R. White ◽  
Peter S. Harlow ◽  
Michael S. McFadden ◽  
...  
Keyword(s):  
Batrachochytrium Dendrobatidis ◽  
Phylogenetic Signal ◽  
Interspecific Variation ◽  
Phylogenetic Position ◽  
Turnover Rates ◽  
Amphibian Skin ◽  
Amphibian Species ◽  
Wide Range ◽  
Skin Morphology ◽  
And Function

Amphibian skin is highly variable in structure and function across anurans, and plays an important role in physiological homeostasis and immune defence. For example, skin sloughing has been shown to reduce pathogen loads on the skin, such as the lethal fungus Batrachochytrium dendrobatidis ( Bd ), but interspecific variation in sloughing frequency is largely unknown. Using phylogenetic linear mixed models, we assessed the relationship between skin turnover rate, skin morphology, ecological traits and overall evidence of Bd -driven declines. We examined skin sloughing rates in 21 frog species from three continents, as well as structural skin characteristics measured from preserved specimens. We found that sloughing rate varies significantly with phylogenetic group, but was not associated with evidence of Bd -driven declines, or other skin characteristics examined. This is the first comparison of sloughing rate across a wide range of amphibian species, and creates the first database of amphibian sloughing behaviour. Given the strong phylogenetic signal observed in sloughing rate, approximate sloughing rates of related species may be predicted based on phylogenetic position. While not related to available evidence of declines, understanding variation in sloughing rate may help explain differences in the severity of infection in genera with relatively slow skin turnover rates (e.g. Atelopus ).

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