Physician testing for HIV in patients treated with tenofovir disoproxil fumarate and lamivudine monotherapy for hepatitis B virus

Sexual Health ◽  
2018 ◽  
Vol 15 (1) ◽  
pp. 89 ◽  
Author(s):  
Jillian S. Y. Lau ◽  
Dilip Ratnam ◽  
Ian Woolley

Previously we found that local patients were often not tested for HIV prior to commencing nucleoside/nucleotide reverse transcription inhibitor (NRTI) therapy for hepatitis B virus. We performed a national cross-sectional cohort study of physician practices via an online survey. A small majority (23/44; 52%) of participants reported always testing their hepatitis B virus patients for HIV prior to NRTI therapy, and 8/44 (18%) reported testing for HIV the majority of the time. Thirteen (30%) respondents reported testing only if risk factors were present. One physician reported a patient seroconverting to HIV while on TDF monotherapy.

1970 ◽  
Vol 42 (3) ◽  
pp. 199-203
Author(s):  
ND Uleanya ◽  
EO Obidike

Background: Hepatitis B Virus (HBV) infection has reached pandemic proportions all over the world with areas of highest prevalence being the sub- Saharan Africa and Southeast Asia. Most deaths related to HBV are due to complications from chronic infection. Acquisition of infection at a younger age is the most important predictor of chronicity. Eradication of HBV is an important but difficult tasks facing public health. HB immunization is the single most important factor in hepatitis B control and was commenced in 2004 in Nigeria.Objectives: To determine the prevalence of Hepatitis B surface antigen (HBsAg) among children in the era of HB immunization, the risk factors of transmission and knowledge of mothers about their HB status.Methods: A cross sectional study carried out on one hundred and forty children aged 18 months to 15 years at the children outpatient clinic (CHOP) of the University of Nigeria Teaching Hospital, Ituku. Hepatitis B surface antigen (HBsAg) was determined using Determine Test Kits and a structured interviewer administered questionnaire administered.Results: Six were positive for HBsAg, giving a prevalence rate of 4.3%. HBsAg was least prevalent among children 1-5 years (2%). None of the children ≤ 5 years who received HB vaccination was positive for HBsAg though one child > 5 years who received the vaccine was positive. Sharing of toothbrushes among siblings was found to be a significantly associated risk factor. Only 6.4% of mothers knew their hepatitis B status.Conclusion: There is a gradual fall in the prevalence of HBsAg in our environment due to HB immunization. Sharing of toothbrushes may be a potent means of transmission of HBV infection.Keywords: HBV, Prevalence, Children, Transmission, HB immunization


2019 ◽  
Author(s):  
Getnet Gedefaw ◽  
Fikadu Waltengus ◽  
Almaz Akililu ◽  
Kihinetu Gelaye

Abstract Objective This study aimed to determine the magnitude of serum HBsAg and the risk factors for Hepatitis B virus infection among pregnant women in Bahir Dar. An institution based cross sectional study was implemented from February 1 to May 1, 2018 among 338 pregnant women attending antenatal care clinic at Felegehiwot referral hospital, Bahir Dar, 2018. Systematic random sampling technique was implemented. Blood sample was taken from 338 study participants and serum was tested for Hepatitis B surface antigen (HBsAg) using Enzyme Linked ImmunoSorbent Assay.Results The overall prevalence of hepatitis B virus infection among pregnant women were 16(4.7%) (95% CI= 2.7, 7.7). Having a history of blood transfusion (AOR=5.2; 95% CI=1.2-22.3), having a history of multiple sexual partners (AOR=4.6; 95% CI=1.1-19.6) and having a history tonsillectomy (traditional surgical procedure) AOR=3.4; 95% CI=1.1-10.1) were the significant risk factors for Hepatitis B virus infection.


Health ◽  
2015 ◽  
Vol 07 (04) ◽  
pp. 459-465 ◽  
Author(s):  
Hussein Ageely ◽  
Mohamed Salih Mahfouz ◽  
Abdelrahim Gaffar ◽  
Erwa Elmakki ◽  
Ibrahim Elhassan ◽  
...  

2015 ◽  
pp. 129-137
Author(s):  
Dinh Binh Tran ◽  
Thi No Ho

Objectives: Study on prevalence of hepatitis B virus in blood donors at Hospital C Danang to determine the percentage of HBsAg-positive in blood donors and identify some risk factors related to hepatitis B virus infection in blood donors. Material and methods: Samples of blood of donors were HBsAg testing by ELISA, the research conducted by descriptive cross-sectional design. The results and conclusions are as follows: Results: HBsAg positive rate was 10.6% (35/330), which accounted for 14.7% males and 7.5% females. HBsAg positive rate high percentage of first-time blood donor group (15.2%), very low proportion of repeat blood donor group (0.9%). Conclusion: HBsAg positive is according to the risk factors for hepatitis B virus transmission associated with surgery, acupuncture, tattooing, infusion, injection, dental treatment, skin sewing and manicure, not associated with history of blood transfusion and endoscopy. Key words: HBsAg, blood donors, HBV.


2013 ◽  
Vol 6 (6) ◽  
Author(s):  
Fatemeh Salem ◽  
Soheila Hekmat ◽  
Mohammad Reza Aghasadeghi ◽  
Foozieh Javadi ◽  
Hossein Gholami ◽  
...  

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