Chlamydia retesting and retest positivity rates: results from a state-wide laboratory data linkage study in Tasmania, 2012–13

Sexual Health ◽  
2017 ◽  
Vol 14 (3) ◽  
pp. 261 ◽  
Author(s):  
Nicola Stephens ◽  
David Coleman ◽  
Kelly Shaw ◽  
Maree O'Sullivan ◽  
Alistair McGregor ◽  
...  
Keyword(s):  
Data Linkage ◽  
Safer Sex ◽  
Laboratory Data ◽  
Partner Notification ◽  
Linkage Study ◽  
Chlamydia Infection ◽  
Socioeconomic Indicators ◽  
Safer Sex Practices ◽  
Positive Results

Background Chlamydia re-infection increases the likelihood of adverse long-term sequelae. Clinical guidelines recommend retesting at 3–12 months for individuals with positive results, to detect re-infections. Retesting and test positivity levels were measured in young people who previously tested positive for chlamydia infection. Methods: All chlamydia tests conducted during 2012–13 in Tasmanian residents aged 15–29 years were linked. Retesting and retest positivity rates were calculated by sex, age, socioeconomic indicators and test timeframe. Results: Retesting rates were higher in females than males at 3 months (14.5%, n = 242/1673 vs 10%, n = 71/721) (P < 0.01) and 12 months (27%, 265/968 vs 24%, 98/410) (P = 0.24). The retesting rate was higher in females living in areas of most disadvantage (35.5%, 154/434) compared with areas of middle and least disadvantage (26% 139/534) (P < 0.01). Males were more likely than females to retest positive at 3 months (35%, 25/71 vs 23%, 55/242) (P < 0.01); retest positivity at 12 months was 32% in both sexes (males 98/140; females 265/968). Retest positivity was higher in males living in areas of least disadvantage (43%, 3/7) compared with middle (24%, 16/67) (P = 0.27) and most (27%, 10/37) (P = 0.09); and higher in females living in areas of least disadvantage (39%, 7/18) compared with middle (24%, 29/121) (P < 0.01) and most (31%, 48/154) (P = 0.02). Conclusions: Retesting rates are low in Tasmania and retest positivity is high, reinforcing the importance of promoting safer sex practices, partner notification and treatment, and retesting.

scholarly journals Frailty Assessed by Administrative Tools and Mortality in Patients With Pneumonia Admitted to the Hospital and ICU: a Population-based Data-linkage Study

2021 ◽  
Author(s):  
Tamas Szakmany ◽  
Joe Hollinghurst ◽  
Richard Pugh ◽  
Ashley Akbari ◽  
Rowena Griffiths ◽  
...  
Keyword(s):  
Data Linkage ◽  
Social Deprivation ◽  
Frailty Index ◽  
Significant Risk ◽  
Population Based ◽  
Linkage Study ◽  
Increased Risk ◽  
Comorbidity Index ◽  
Population Scale

Abstract Background: The ideal method of identifying frailty is uncertain, and data on long-term outcomes is relatively limited. We examined frailty indices derived from population-scale linked data on Intensive Care Unit (ICU) and hospitalised non-ICU patients with pneumonia to elucidate the influence of frailty on mortality.Methods: Longitudinal cohort study between 2010-2018 using population-scale anonymised data linkage of healthcare records for adults admitted to hospital with pneumonia in Wales. Primary outcome was in-patient mortality. Age, hospital frailty risk score (HFRS), electronic frailty index (eFI), Charlson comorbidity index (CCI), and social deprivation index were entered in the multivariate regression models.Results: Of the 107,188 patients, mean (SD) age was 72.6 (16.6) years, 50% were men. The two frailty indices and the comorbidity index had an increased risk of mortality for individuals with an ICU admission. Advancing age, increased frailty and comorbidity affected short- and long-term mortality. For predicting inpatient deaths, the CCI and HFRS based models were similar, however for longer term outcomes the CCI based model was superior. Discussion: Frailty and comorbidity are significant risk factors for patients admitted to hospital with pneumonia. Frailty and comorbidity scores based on administrative data have only moderate ability to predict outcome.

Long term risk of severe retinopathy in childhood‐onset type 1 diabetes: a data linkage study

2017 ◽  
Vol 206 (9) ◽  
pp. 398-401 ◽  
Author(s):  
Mary White ◽  
Matthew A Sabin ◽  
Costan G Magnussen ◽  
Michele A O'Connell ◽  
Peter G Colman ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Data Linkage ◽  
Linkage Study ◽  
Childhood Onset ◽  
Onset Type

Testing for chlamydial infection: are we meeting clinical guidelines? Evidence from a state-level laboratory data linkage analysis for 15- to 29-year-olds

Sexual Health ◽  
2017 ◽  
Vol 14 (6) ◽  
pp. 507 ◽  
Author(s):  
Nicola Stephens ◽  
David Coleman ◽  
Kelly Shaw ◽  
Maree O' Sullivan ◽  
Alistair McGregor ◽  
...  
Keyword(s):  
Clinical Guidelines ◽  
Linked Data ◽  
Data Linkage ◽  
Laboratory Data ◽  
State Level ◽  
Sexually Active ◽  
Socioeconomic Indicators ◽  
Healthcare Settings ◽  
Population Prevalence ◽  
Testing Coverage

Background Clinical guidelines recommend annual chlamydia tests for all sexually active people aged 15–29 years. This study measured adherence to these guidelines and compared testing rates to the projected levels required to reduce chlamydia prevalence. Methods: All chlamydia tests conducted in Tasmania during 2012–13, for residents aged 15–29 years, were linked. Data linkage allowed individuals who had multiple tests across different healthcare settings to be counted only once each year in analyses. Rates of testing and test positivity by age, sex, rebate status and socioeconomic indicators were measured. Results: There were 31 899 eligible tests conducted in 24 830 individuals. Testing coverage was higher in females (21%, 19 404/92 685) than males (6%, 5426/98 123). Positivity was higher in males (16%, 862/5426) than females (10%, 1854/19 404). Most tests (81%, 25 803/31 899) were eligible for a rebate. Positivity was higher in females with non-rebatable tests (12%, 388/3116 compared with those eligible for a rebate (9%, 1466/16 285). More testing occurred in areas of middle disadvantage (10%, 9688/93 678) compared with least (8%, 1680/21 670) and most (10%, 7284/75 460) (both P < 0.001) disadvantaged areas. Higher test positivity was found in areas of most-disadvantage (11%, 822/7284) compared with middle- (10%, 983/9688) and least- (8%, 139/1680) disadvantaged areas. Conclusions: Chlamydia testing rates are lower than recommended levels. Sustaining the current testing rates in females aged 20–24 years may reduce population prevalence within 10 years. This study meets key priorities of national strategies for chlamydia control by providing a method of monitoring testing coverage and evidence to evaluate prevention programs.

scholarly journals Tropical Australian Health-Data Linkage Shows Excess Mortality Following Severe Infectious Disease Is Present in the Short-Term and Long-Term after Hospital Discharge

Healthcare ◽  
2021 ◽  
Vol 9 (7) ◽  
pp. 901
Author(s):  
Oyelola A. Adegboye ◽  
Emma S. McBryde ◽  
Damon P. Eisen
Keyword(s):  
Infectious Disease ◽  
Infectious Diseases ◽  
Data Linkage ◽  
Aged Care ◽  
Linkage Study ◽  
Residential Aged Care ◽  
Indigenous Status ◽  
Australian Health ◽  
Male Sex

Background: In this study, we aimed to assess the risk factors associated with mortality due to an infectious disease over the short-, medium-, and long-term based on a data-linkage study for patients discharged from an infectious disease unit in North Queensland, Australia, between 2006 and 2011. Methods: Age-sex standardised mortality rates (SMR) for different subgroups were estimated, and the Kaplan-Meier method was used to estimate and compare the survival experience among different groups. Results: Overall, the mortality rate in the hospital cohort was higher than expected in comparison with the Queensland population (SMR: 15.3, 95%CI: 14.9–15.6). The long-term mortality risks were significantly higher for severe infectious diseases than non-infectious diseases for male sex, Indigenous, residential aged care and elderly individuals. Conclusion: In general, male sex, Indigenous status, age and comorbidity were associated with an increased hazard for all-cause deaths.

scholarly journals Patterning in Patient Referral to and Uptake of a National Exercise Referral Scheme (NERS) in Wales from 2008 to 2017: A Data Linkage Study

2020 ◽  
Vol 17 (11) ◽  
pp. 3942
Author(s):  
Kelly Morgan ◽  
Muhammad Rahman ◽  
Graham Moore
Keyword(s):  
Mental Health ◽  
Data Linkage ◽  
Linkage Study ◽  
Mental Health Referrals ◽  
Linkage Design ◽  
Uptake Rates ◽  
Multilevel Logistic Regression Model ◽  
Exercise Referral ◽  
Exercise Referral Scheme

Exercise referral schemes have shown small but positive impacts in randomized controlled trials (RCTs). Less is known about the long-term reach of scaled up schemes following a RCT. A RCT of the National Exercise Referral Scheme (NERS) in Wales was completed in 2010, and the scheme scaled up across Wales. In this study, using a retrospective data linkage design, anonymized NERS data were linked to routine health records for referrals between 2008 and 2017. Rates of referral and uptake were modelled across years and a multilevel logistic regression model examined predictors of uptake. In total, 83,598 patients have been referred to the scheme and 67.31% of eligible patients took up NERS. Older adults and referrals for a musculoskeletal or level four condition were more likely to take up NERS. Males, mental health referrals, non-GP referrals and those in the most deprived groupings were less likely to take up NERS. Trends revealed an overall decrease over time in referrals and uptake rates among the most deprived grouping relative to those in the least deprived group. Findings indicate a widening of inequality in referral and uptake following positive RCT findings, both in terms of patient socioeconomic status and referrals for mental health.

The Link between Male Genital Anomalies and Adult Male Reproductive Disorders: A Population-Based Data Linkage Study Spanning Over 40 Years

2018 ◽  
Author(s):  
Francisco Schneuer ◽  
Elizabeth Milne ◽  
Sarra E. Jamieson ◽  
Gavin Pereira ◽  
Michele Hansen ◽  
...  
Keyword(s):  
Adult Male ◽  
Data Linkage ◽  
Population Based ◽  
Linkage Study ◽  
Reproductive Disorders ◽  
Over 40 Years ◽  
Male Genital
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