169 Comparison of pregnancy outcomes in dairy heifers artificially inseminated with sexed semen deposited in the uterine horns versus the uterine body

2020 ◽  
Vol 32 (2) ◽  
pp. 211
Author(s):  
S. Kirks ◽  
R. Palomares ◽  
P. Melendez ◽  
M. Ferrer ◽  
A. Hoyos ◽  
...  
Keyword(s):  
Cell Damage ◽  
Animal Health ◽  
Genetic Selection ◽  
Prostaglandin F2α ◽  
Freezing Process ◽  
Dairy Heifers ◽  
Normal Ranges ◽  
Sexed Semen ◽  
On Farm ◽  
Uterine Body

The use of sexed semen (SS) for AI of cattle has resulted in lower pregnancy per timed AI (P/TAI) compared with conventional semen. This has been attributed to lower sperm dose and cell damage during the cell sorting-freezing process. Horn AI is a common practice in equines and canines to improve pregnancy rate when using low sperm doses. The objective was to compare P/TAI and pregnancy loss (PL) in dairy heifers inseminated with SS deposited in the uterine horn (UH) ipsilateral to the ovary containing the preovulatory follicle (POF) versus TAI in the uterine body (UB). This study was performed on two dairy farms in Georgia (A and B). On farm A, 74 Holstein heifers (12 months old) received a 5-day Cosynch + controlled internal drug release (CIDR) protocol including an intravaginal insert (Eazi-Breed CIDR, Zoetis Animal Health) containing 1.38g of progesterone for 5 days and a dose of gonadotrophin-releasing hormone (GnRH) intramuscularly (100µg, 2mL of Factrel, Zoetis Animal Health). At CIDR removal, heifers received a dose of prostaglandin F2α (PGF2α) intramuscularly (25mg, 5mL of Lutalyse, Zoetis Animal Health) and again 24h later; 72h after CIDR removal, heifers received 100µg of GnRH intramuscularly and TAI with frozen-thawed SS. On farm B, 237 Holstein×Jersey heifers (12 months old) received a modified 5-day Cosynch + CIDR. This protocol was similar to that on farm A but did not include GnRH at the time of CIDR insertion or a second dose of PGF2α 24h after CIDR removal. Immediately before TAI, heifers were examined using transrectal ultrasonography (TRUS) to determine on which ovary the POF was present. Each heifer was randomly assigned to TAI using SS in either the UH ipsilateral to the ovary containing the POF (n=150; farm A, n=32; farm B, n=118) or the UB regardless of where the POF was identified (n=161; farm A, n=42; farm B, n=119). Pregnancy was diagnosed 32 days after TAI using TRUS to determine P/TAI. Heifers diagnosed pregnant were re-examined using TRUS at 60 days of gestation to assess PL. Data were analysed using PROC LOGISTIC and the chi-square test of SAS (SAS Institute Inc.). Heifers that received SS in the UH had adequate P/TAI (50.6% (76/150); farm A: 50.0% (16/32); farm B: 50.8% (60/118)), which tended to be numerically greater (P=0.12) than that observed in heifers receiving SS in the UB (43.4% (70/161); farm A: 40.5% (17/42); farm B: 44.5% (53/119)). In addition, PL was not different between groups and was within normal ranges for dairy heifers (10.0 and 9.4% for UH and UB, respectively). In conclusion, TAI of dairy heifers with SS deposited in the UH ipsilateral to the ovary containing the POF resulted in adequate P/TAI, which was 7.2% greater than TAI in the UB. Horn AI with SS might become a valuable tool for optimising reproductive efficiency and genetic selection of dairy herds.

scholarly journals High Heritabilities for Antibiotic Usage Show Potential to Breed for Disease Resistance in Finishing Pigs

Antibiotics ◽  
2021 ◽  
Vol 10 (7) ◽  
pp. 829
Author(s):  
Wim Gorssen ◽  
Dominiek Maes ◽  
Roel Meyermans ◽  
Jürgen Depuydt ◽  
Steven Janssens ◽  
...  
Keyword(s):  
Pathogenic Bacteria ◽  
Animal Health ◽  
Molecular Genetic ◽  
Genetic Correlations ◽  
Genetic Selection ◽  
Antibiotic Usage ◽  
Finishing Pigs ◽  
Production Traits ◽  
Parenteral Antibiotic ◽  
On Farm

The use of antimicrobials in animal production is under public debate, mainly due to the risk of transfer of resistance to pathogenic bacteria in humans. Therefore, measures have been taken during the last few decades to reduce antibiotic usage in animals, for instance, by national monitoring programmes and by improving animal health management. Although some initiatives exist in molecular genetic selection, quantitative genetic selection of animals towards decreased antibiotic usage is an underexplored area to reduce antibiotic usage. However, this strategy could yield cumulative effects. In this study, we derived new phenotypes from on-farm parenteral antibiotic records from commercially grown crossbred finishing pigs used in the progeny test of Piétrain terminal sires to investigate the heritability of antibiotics usage. Parenteral antibiotic records, production parameters and pedigree records of 2238 full-sib pens from two experimental farms in Belgium between 2014 and 2020 were analysed. Heritability estimates were moderate (18–44%) for phenotypes derived from all antibiotic treatments, and low (1–15%) for phenotypes derived from treatments against respiratory diseases only. Moreover, genetic correlations between these new phenotypes and mortality were low to moderate (0.08–0.60) and no strong adverse genetic correlations with production traits were found. The high heritabilities and favourable genetic correlations suggest these new phenotypes, derived from on-farm antibiotics records, to be promising for inclusion in future pig breeding programs to breed for a decrease in antibiotics usage.

scholarly journals High heritabilities for antibiotic usage show potential to breed for disease resistance in finishing pigs

2021 ◽  
Author(s):  
Wim Gorssen ◽  
Dominiek Maes ◽  
Roel Meyermans ◽  
Jurgen Depuydt ◽  
Steven Janssens ◽  
...  
Keyword(s):  
Pathogenic Bacteria ◽  
Animal Health ◽  
Molecular Genetic ◽  
Genetic Correlations ◽  
Genetic Selection ◽  
Antibiotic Usage ◽  
Finishing Pigs ◽  
Production Traits ◽  
Parenteral Antibiotic ◽  
On Farm

The use of antimicrobials in animal production is under public debate, mainly due to the risk of transfer of resistance to pathogenic bacteria in humans. Therefore, measures have been taken during the last decades to reduce antibiotic usage in animals, for instance by national monitoring programmes and by improving animal health management. Although some initiatives exist in molecular genetic selection, quantitative genetic selection of animals towards decreased antibiotic usage is an underexplored area to reduce antibiotic usage. However, this strategy could yield cumulative effects. In this study we derived new phenotypes from on-farm parenteral antibiotic records from commercially grown crossbred finishing pigs used in the progeny test of Pietrain terminal sires to investigate the heritability of antibiotics usage. Parenteral antibiotic records, production parameters and pedigree records of 2238 full-sib pens from two experimental farms in Belgium between 2014 and 2020 were analysed. Heritability estimates were moderate (18-44%) for phenotypes derived from all antibiotic treatments, and low (1-15%) for phenotypes derived from treatments against respiratory diseases only. Moreover, genetic correlations between these new phenotypes and mortality were low to moderate (0.08-0.60) and no strong adverse genetic correlations with production traits were found. The high heritabilities and favourable genetic correlations suggest these new phenotypes derived from on-farm antibiotics records to be promising for inclusion in future pig breeding programs to breed for a decrease in antibiotics usage.

38 APPLICATION OF A FIVE-DAY PROGESTERONE-BASED SYNCHRONIZATION PROTOCOL FOR TIMED AI WITH SEXED SEMEN IN DAIRY HEIFERS

2010 ◽  
Vol 22 (1) ◽  
pp. 177
Author(s):  
M. B. Rabaglino ◽  
C. A. Risco ◽  
M. J. Thatcher ◽  
J. E. P. Santos ◽  
W. W. Thatcher
Keyword(s):  
New York ◽  
Logistic Regression ◽  
Animal Health ◽  
Random Effect ◽  
Management Program ◽  
Dairy Heifers ◽  
Reproductive Management ◽  
Sexed Semen ◽  
Pfizer Animal Health ◽  
Synchronization Protocol

It is expected that pregnancy per AI with sexed semen would be 70 to 75% of that with conventional semen, and the use of sexed semen with timed AI (TAI) protocols is discouraged (DeJarnette et al. 2009 Theriogenology 71, 49-58). It was hypothesized that the 5-day Co-Synch + CIDR (controlled internal drug-release) protocol with 1 injection of PGF2α would be an acceptable reproductive management program for TAI of dairy heifers with sexed semen. The objectives were to compare pregnancy per TAI (P/TAI) using conventional or sexed semen for the first TAI (experiment 1), and to evaluate P/TAI of a reproductive management program with sexed semen for the first TAI and sexed or conventional semen for the second TAI (experiment 2). A total of 1,000 Holstein heifers between 13 to 14 months of age were synchronized with the 5-day Co-Synch + CIDR protocol, that consisted of an administration of GnRH (100 μg i.m. Cystorelin®, Merial Ltd., Iselin, NJ, USA) and a CIDR insert containing 1.38 g of progesterone inserted at Day 0; on Day 5 the CIDR was removed and one injection of PGF2α (25 mg, i.m. Lutalyse®, Pfizer Animal Health, New York, NY, USA) administered; on Day 8 a second injection of GnRH was administered concurrent with TAI. In experiment 1, 198 heifers were assigned randomly to be TAI with conventional (n = 98) or sexed (n = 100) semen for the first TAI. Commercial straws with sexed or conventional semen were obtained from 2 sires. In experiment 2, a total of 802 heifers received TAI to the first service with sexed semen. For the resynchronized TAI, nonpregnant heifers at 32 days after the first TAI were resynchronized with the 5-day Co-Synch + CIDR and were TAI with either sexed semen (n = 114) or with conventional semen (n = 373). Pregnancy per TAI to first and second TAI was analyzed by logistic regression using the GLIMMIX procedure of SAS (SAS Version 9.1 for Windows, SAS Institute, Cary, NC, USA) with heifer treated as a random effect. In experiment 1, P/TAI was 51.0% and 42.0% at 45 days for conventional and sexed semen, respectively (P = 0.1). Pregnancy per TAI with sexed semen was 82.3% of conventional semen. In experiment 2, P/TAI at first service with sexed semen was 35.9% at 45 days after TAI. For the second TAI, P/TAI was 40.4% with sexed semen at 45 days and 59.2% with conventional semen at 60 days (P < 0.001). As expected, P/TAI was lower with sexed compared to conventional semen. Nevertheless, the application of the 5-day Co-Synch + CIDR protocol with one injection of PGF2α, as a reproductive management program for TAI of dairy heifers, achieved an acceptable P/TAI with sexed semen. We conclude that sexed semen can be used with TAI to effectively manage reproduction in dairy heifers by removing the challenges of detection of estrus and increase the number of females born.

The use of fixed time artificial insemination programmes for the use of sexed semen in block calving dairy heifers

Livestock ◽  
2021 ◽  
Vol 26 (3) ◽  
pp. 124-130
Author(s):  
Mike Kerby ◽  
Tom Clarke ◽  
Tom Angel ◽  
Kythé Mackenzie
Keyword(s):  
Artificial Insemination ◽  
Prostaglandin F2α ◽  
Cost Benefit ◽  
Fixed Time ◽  
Reproductive Efficiency ◽  
Costs And Benefits ◽  
Dairy Heifers ◽  
Conception Rates ◽  
Sexed Semen

In seasonal block calving herds reproductive efficiency can have a significant impact on productivity and profitability. Within this it is key that the nulliparous heifers calve down promptly in the block, and if these heifers can have heifer calves it will expediate genetic gain. There is extensive research into the conception rates of differing protocols and the literature is reviewed to support the choice of protocol used in the subsequent case study. The case study uses a 6-day progesterone protocol with two injections of prostaglandin F2α and sexed semen; it demonstrated acceptable conception rates as well as the variability that can occur between different bulls' semen straws. Finally, the case study assesses the costs and benefits of the synchronisation programme and concludes a cost benefit of £88.55 per heifer.

Economics of respiratory disease in dairy replacement heifers

2020 ◽  
Vol 21 (2) ◽  
pp. 143-148
Author(s):  
Michael W. Overton
Keyword(s):  
Respiratory Disease ◽  
Milk Production ◽  
Incident Case ◽  
Data Set ◽  
Dairy Heifers ◽  
The Usa ◽  
History Of ◽  
On Farm ◽  
The Impact ◽  
Selective Culling

AbstractBovine respiratory disease (BRD) is a frequent disease concern in dairy cattle and is most commonly diagnosed in young dairy heifers. The impact of BRD is highly variable, depending on the accuracy and completeness of detection, effectiveness of treatment, and on-farm culling practices. Consequences include decreased rate of weight gain, a higher culling risk either as heifers or as cows, delayed age at first service, delayed age at first calving, and in some cases, lower future milk production. In this data set of 104,100 dairy replacement heifers from across the USA, 36.6% had one or more cases diagnosed within the first 120 days of age with the highest risk of new cases occurring prior to weaning. Comparison of the raising cost for heifers with BRD and those without a recorded history of BRD resulted in an estimated cost per incident case occurring in the first 120 days of age of $252 or $282, depending upon whether anticipated future milk production differences were considered or not. Current market conditions contributed to a cost estimate that is significantly higher than previously published estimates, driven in part by the losses associated with selective culling of a subset of heifers that experienced BRD.

Strategie e strumenti per la valorizzazione delle produzioni nella filiera bovina: il fattore genoma

2012 ◽  
pp. 63-83
Author(s):  
Francesco Zecca ◽  
Elisabetta Capocchi
Keyword(s):  
Bovine Genome ◽  
Animal Health ◽  
Genetic Selection ◽  
Analytical Framework ◽  
Cattle Industry ◽  
Cattle Feed ◽  
Use Of Technology ◽  
Representative Species ◽  
Working Set ◽  
Target Characteristics

The aim of the project was to examine the features involved in product quality and animal health for the purposes of genetic selection in order to achieve the best quality in each of the species and/or breeds under consideration. Among the tasks carried out the working group had to verify the socio-economic development of the most satisfactory end results as determined by the working set of genetic selections in the light of continuous advances in knowledge regarding the bovine genome. The analysis was limited to cattle as they were considered the most representative species for the purpose of the study. The study started with an analysis of the sector to investigate the proactive dynamics concerning the use of technology in the cattle industry The approach used is one which has become customary in studies examining issues in this sector related to the system of farming/livestock and which allows us to detect not only the most crucial quantitative but also qualitative aspects that exist and have been established among the various components of the system, with particular reference to the types of productive performance which are determined by the use of different technical patterns, especially those related to improvement and genetic selection. The study's aim was to follow the analytical framework of the supply chain in order to highlight important conditions that contribute to an interpretation of the key economic characteristics for the selective breeding industry under analysis. All this is due to the gradual revelation of the genetic basis of biodiversity by means of genome sequencing. Thanks to genomics, subjects to be used for propagation can be selected in terms of the target characteristics to be achieved, such as greater energy efficiency, resulting in the ability to produce better cattle feed, more resistance to disease, or a reduction in environmental impact by reducing emissions of methane gas. Regarding the methodology adopted, an examination of the context is followed by an evaluation of the most suitable production factors for the enhancement of the cattle population and the article concludes with some suggestions for possible future interventions.

scholarly journals Commercial practice of out-wintering dairy heifers in Great Britain

2020 ◽  
Vol 82 ◽  
pp. 161-169
Author(s):  
Norton E. Atkins ◽  
Keith E. Walley ◽  
Liam A. Sinclair
Keyword(s):  
Great Britain ◽  
High Performance ◽  
Animal Health ◽  
Live Weight ◽  
Herd Size ◽  
Dairy Farmers ◽  
Commercial Practice ◽  
Dairy Heifers ◽  
Supplementary Feed ◽  
Strip Grazing

The majority of dairy cattle in Great Britain (GB) are housed during winter but replacement heifers are out-wintered on some farms, a practice that may reduce the need for high capital-cost housing and facilitate herd expansion. Dairy farmers that were out-wintering replacement heifers in GB in 2012 were surveyed to determine current practice and attitudes. A typical system involved heifers strip grazing pasture or a crop, with baled grass silage as supplementary feed; strongly resembling outdoor wintering systems in New Zealand. Many used more than one grazed forage; predominantly, pasture on 68%, kale on 53% and fodder beet on 33% of farms. Supplementary feed was 44% of the diet in younger, and 35% in older heifers. Although farms were approximately three times larger than the national average and 60% were expanding, expanding herd size was not the primary reason for out-wintering, with the main reasons being to reduce cost and improve animal health and welfare. Farmers that out-wintered heifers typically reported good animal average dairy gain of 0.6 kg/d and high body condition, however, this contrasts with some measured performance in GB. Farmers may benefit from accurate feed allocation and monitoring heifer live weight during winter to ensure high performance.  

scholarly journals Effects of Enriched Charcoal as Permanent 0.2% Feed-Additive in Standard and Low-Protein Diets of Male Fattening Turkeys: An On-Farm Study

Animals ◽  
2019 ◽  
Vol 9 (8) ◽  
pp. 541
Author(s):  
Hinz ◽  
Stracke ◽  
Schättler ◽  
Kemper ◽  
Spindler
Keyword(s):  
Animal Health ◽  
Matter Content ◽  
Feed Additive ◽  
Standard Diet ◽  
Dry Matter Content ◽  
Positive Effects ◽  
Low Protein ◽  
Protein Reduction ◽  
On Farm ◽  
Experimental Group

Wet litter is the most important cause of footpad dermatitis in poultry, this in turn being a highly relevant animal-related welfare indicator. This field study was subdivided into two experiments. In Experiment 1, the standard diet was supplemented by 0.2% enriched charcoal, being a non-specific absorber and therefore might be promising in reducing faecal moisture. In Experiment 2, the experimental group received a reduced crude protein diet during weeks 6–13, combined with a 0.2% enriched charcoal supplementation. The trials were each conducted with two batches on three farms under on-farm conditions. The animals were observed at 6, 10, 14 and 18 weeks of age to collect data on body weight and different health parameters. The mortality and litter samples were analysed after slaughtering. In Experiment 1, performance and health were not affected despite higher dry matter content of the litter. In Experiment 2, the weight of birds receiving the protein-reduced diet was decreased significantly throughout the experiment. However, the slaughter weight did not differ. The mortality was reduced by 0.5% in the experimental group. Therefore, it was concluded that 0.2% of enriched charcoal is not a valuable feed-additive regarding animal health, while temporary protein reduction might have positive effects.

Animal health : present and future

1977 ◽  
Vol 281 (980) ◽  
pp. 181-191
Keyword(s):  
Disease Surveillance ◽  
High Performance ◽  
Large Scale ◽  
Animal Health ◽  
Genetic Selection ◽  
New Production ◽  
Financial Investment ◽  
Veterinary Surgeons ◽  
Acceptable Quality ◽  
High Standards

The importance of the health of farm livestock is considered in relation to the need to economically produce enough human food of an acceptable quality. The control and eradication of important diseases is discussed. Success in this work has allowed the development of high performance breeds by genetic selection. It has also encouraged the development of large scale units and intensive husbandry techniques. These new production methods require high standards of management from all concerned, and represent considerable financial investment. Biochemists, geneticists, physiologists, veterinary surgeons, all have a part to play in the modern livestock industry. The work of the State Veterinary Service is seen as catalytic. The possible development of a disease surveillance unit is discussed, also the type of information required by both veterinary surgeons and farmers.

107 FACTORS THAT INFLUENCE FERTILITY IN AN IVF EMBRYO TRANSFER PROGRAM IN DAIRY HEIFERS

2016 ◽  
Vol 28 (2) ◽  
pp. 183 ◽  
Author(s):  
L. C. Carrenho-Sala ◽  
R. V. Sala ◽  
M. Fosado ◽  
D. C. Pereira ◽  
S. Garcia ◽  
...  
Keyword(s):  
Embryo Transfer ◽  
Pregnancy Loss ◽  
Embryo Quality ◽  
Prostaglandin F2α ◽  
Transfer Program ◽  
Dairy Heifers ◽  
Embryo Transfer Program ◽  
Embryo Stage ◽  
Major Factors

A retrospective study was performed to evaluate factors that influence pregnancy per embryo transfer (P/ET) in an IVF-embryo transfer program. A total of 5026 fresh in vitro-produced embryos were transferred during 2014 and evaluated for effects of embryo quality, embryo stage, size of corpus luteum (CL; 18–19.9 mm or ≥20 mm), interval from GnRH to embryo transfer, number of previous embryo transfer (0, 1, 2, 3, ≥4); and interaction of embryo stage and interval from GnRH to embryo transfer. One group (n = 850) had detection of oestrus after prostaglandin F2α application but most heifers (n = 4176) received fixed timed embryo transfer after a 5-day CIDR-Synch protocol: Day –8 CIDR inserted; Day –3 CIDR removed and prostaglandin F2α; Day –2 prostaglandin F2α; Day 0 GnRH. Ultrasound was performed on Day 6 after GnRH or oestrus to measure CL size and on Day 32 and 60 to determine pregnancy. Data for P/ET were analysed by logistic regression (LOGISTIC procedure, SAS 9.4). Embryo quality influenced P/ET at Day 32 [Grade 1 48.4% (1273/2631) v. Grade 2 37.6% (900/2395); P < 0.01] and at Day 60 [Grade 1 38.9% (1023/2631) v. Grade 2 29.0% (694/2395); P < 0.01], and altered pregnancy loss [Grade 1 19.6% (250/1273) v. Grade 2 22.9% (206/900); P = 0.03]. Stage of the embryo also had an effect on P/ET at Day 32 [Stage 6 35.5%a (582/1641), Stage 7 46.3%b (1431/3092), and Stage 8 54.6%c (160/293); P < 0.01] and at Day 60 [Stage 6 28.2%a (462/1641), Stage 7 36.6%b (1131/3092), and Stage 8 41.6%b (122/293); P < 0.01], but did not affect pregnancy loss (P = 0.22). Interestingly, interval from GnRH (or oestrus) until embryo transfer did not affect P/ET at Day 32 (P = 0.10), 60 (P = 0.23), or pregnancy loss (P = 0.3), nor was there an interaction between interval and embryo stage at Day 32 (P = 0.77), 60 (P = 0.96) or pregnancy loss (P = 0.55). As shown in Table 1, embryo stage 6 was always the lowest and stage 8 always the greatest P/ET regardless of interval from GnRH to embryo transfer. Size of CL also did not affect P/ET at Day 32 (P = 0.09), 60 (P = 0.21), or pregnancy loss (P = 0.90). Number of previous embryo transfer also did not alter P/ET at Day 32 [0 = 43.3% (886/2046), 1 = 44.1% (639/1450), 2 = 43.4% (444/1024), 3 = 42.6% (146/343), and ≥4 = 35.6% (58/163); P = 0.33] or 60 (P = 0.51) or pregnancy loss (P = 0.12). In conclusion, embryo stage and quality are the major factors that impacted P/ET in this study, with surprisingly little effect of interval from GnRH to embryo transfer, size of the CL, and number of previous embryo transfer. Thus, recipient programs for IVF-embryo transfer can be designed with substantial flexibility. Table 1.Effect of embryo stage and recipient synchrony on pregnancies per embryo transfer on Day 32 in recipient dairy heifers

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