195 Are the Spectral Doppler Indices of the Ovarian Arteries Predictive of Ovulatory Responses and Embryo Yields in Superovulated Ewes?

2018 ◽  
Vol 30 (1) ◽  
pp. 238
Author(s):  
M. E. F. Oliveira ◽  
Y. Tarasevych ◽  
W. R. R. Vicente ◽  
P. M. Bartlewski
Keyword(s):  
Resistance Index ◽  
Peak Systolic Velocity ◽  
Ovarian Response ◽  
Embryo Viability ◽  
Mean Velocity ◽  
Ovarian Artery ◽  
Diastolic Velocity ◽  
Spectral Doppler ◽  
Left And Right ◽  
Doppler Indices

Increased uterine and ovarian blood flow seems to be related to the effectiveness of ovarian response to hormonal superstimulation in mares (Witt et al. 2012 Theriogenology 77, 1406-1414). Similar studies do not exist for sheep. Nineteen Santa Inês ewes were subjected to a 9-day CIDR® priming and superovulatory (SOV) treatment with 200 mg of porcine (p)FSH per ewe given twice daily for 4 consecutive days in decreasing doses and initiated 6 days after CIDR® insertion. Ten ewes received an IM injection of oestradiol benzoate (EB, 350 μg) at the time of CIDR® insertion (group E); the remaining animals served as controls (group C). The ewes were placed in a pen with rams for 3 days after CIDR® removal. The embryos were recovered surgically 6 days after the CIDR® removal. Transrectal ultrasonographic examinations (Doppler mode) using MyLab VET 30 scanner (Esaote, Genoa, Italy) equipped with a linear-array (6- to 8-MHz) transducer were performed once a day throughout the SOV treatment (Days 1 to 4) to determine the velocimetric indices of the left and right ovarian arteries: flow velocity integral (FVI); peak systolic velocity (SVp); mean velocity (Vm); end-diastolic velocity (EDV); vascular resistance index [RI = (SVp – EDV)/SVp]; and pulsatility index [PI = (SVp – EDV)/Vm]. All spectral data were obtained from a longitudinal subovarian segment of the ovarian artery using a gate ranging from 2 to 3 mm (~two-thirds of the vessel’s diameter) and insonation angle ≤60°. There were no differences (P > 0.05) in ovarian responses and embryo yields/quality between left and right ovaries/uterine horns flashed or between EB-treated and control ewes. Mean EDV and Vm were greater (P < 0.05) in group C compared with group E on Days 1 and 2, and mean Vp was greater (P < 0.05) in group C ewes on Day 3 of the SOV treatment. In group E, there were 5 significant correlations between the spectral Doppler indices (RI, PI, and EDV) of the ovarian arteries recorded on Days 2 and 4 and SOV responses (numbers of degenerated embryos, unfertilized eggs, and luteinized unovulated follicles characterised by a lack of ovulatory stigmata). In group C, 7 significant correlations were found between Vp, EDV, Vm, and RI on Days 1, 2, and 3 and numbers/percentages of degenerated embryos, numbers of prematurely regressed luteal structures (pale, ≤5 mm in diameter), and embryo viability rates (percentage of transferrable quality embryos). When ultrasonographic and SOV data were analysed separately for the left and right ovarian artery/uterine horn, multiple significant correlations were found between the velocimetric indices and SOV responses but they varied among days, the 2 ovaries, and the 2 groups of animals studied. These results may be interpreted to suggest that intrinsic gonadal factors remain a significant barrier precluding the prediction of SOV outcomes from haemodynamic changes in ovine ovarian arteries. Velocimetric indices determined in the ovarian arteries appear to have limited prognostic value during the application of different SOV protocols in ewes.

scholarly journals 603 Endothelial dysfunction is associated with hypertensive disorder during pregnancy

2021 ◽  
Vol 23 (Supplement_G) ◽  
Author(s):  
Carlo Maria Avallone ◽  
Martina Nuzzo ◽  
Irene Rota ◽  
Nicola Persico ◽  
Stefano Carugo ◽  
...  
Keyword(s):  
Brachial Artery ◽  
Vascular Reactivity ◽  
Resistance Index ◽  
Peak Systolic Velocity ◽  
First Trimester ◽  
Hypertensive Disorder ◽  
Mean Velocity ◽  
Brachial Artery Diameter ◽  
Diastolic Velocity ◽  
In Pregnancy

Abstract Aims Arterial hypertension (AH) is one of the main determinants of clinical disorders during pregnancy affecting 2% to 10% of pregnancies with a substantial public health impact. Both endothelial injury and increased vascular reactivity have been reported to be involved in the pathogenesis of pre-eclampsia syndrome. Abnormal patterns in brachial artery Doppler velocities have been shown to be predictive of pre-eclampsia in first trimester. The aim of this study is to investigate whether flow-mediated dilation (FMD) and Doppler flow derived-parameters can predict the occurrence of AH. Methods and results The study population consisted of pregnant women (mean age 32 years) who had been referred to the IRCCS Fondazione Ca’ Granda Policlinico of Milan. None of them had any medical issues and was taking any medications at the time of pregnancy. FMD was performed on left brachial artery according to expert recommendation. Measurements of brachial artery diameter and flow have been collected at rest, shortly before cuff release and then 5-, 15-, 30-, 60-, and 90-s during hyperaemia phase. Among Doppler measurements, systolic and diastolic velocity (Vs and Vd, respectively) as well as mean velocity (mean V) were considered. In addition, the pulsatility index (PI) and resistance index (RI) were calculated. A 3-months follow-up was planned in order to detect the presence of AH. All data were expressed as the median. U-test (Mann–Whitney analysis) was performed to test difference among hypertensives and non-hypertensives We recruited 48 women (median age 32 yeas) whose 4 (8.5%) developed AH during pregnancy. These latter had statistically significant higher systolic velocity measured at 5 s after the release of distal occlusion (126 cm/s vs. 173 cm/s; P &lt; 0.05). No other velocity Doppler data [diastolic velocity (Vd), mean velocity (mean V), PI, RI, TAMAX, and TAMEAN] showed a statistical significant association with AH development. Conclusions The present study suggests that the vascular assessment through Doppler during FMD procedure may foresee the development of hypertensive disorder in pregnancy. Our result provides the first evidence that the peak systolic velocity of brachial artery may represent a marker of early endothelial activation or damage, that can be directly involved in the pathophysiological mechanisms of the hypertensive disorders in pregnancy.

Utility of color duplex sonography in the assessment of efficacy of the stellate ganglion blockade

2003 ◽  
Vol 44 (5) ◽  
pp. 494-497 ◽  
Author(s):  
M. Çeliktas ◽  
H. Birbiçer ◽  
K. Aikimbaev ◽  
H. Özbek ◽  
E. Akgül ◽  
...  
Keyword(s):  
Upper Extremity ◽  
Nervous Activity ◽  
Stellate Ganglion ◽  
Peak Systolic Velocity ◽  
Duplex Sonography ◽  
Sympathetic Nervous Activity ◽  
Hemodynamic Changes ◽  
Mean Velocity ◽  
Diastolic Velocity ◽  
Spectral Doppler

Purpose: To assess the hemodynamic changes in the upper extremity arteries after sympathetic ganglion blockade (SGB) by using spectral Doppler parameters and to determine the applicability of these parameters for the evaluation of SGB efficacy. Material and Methods: Spectral Doppler parameters (peak systolic velocity (PSV), end diastolic velocity (EDV), mean velocity (mean V), flow volume, resistive and pulsatility indices (RI, PI), inner arterial diameters (intima to intima) (D) with simultaneous recordings of heart rate (HR), systolic and diastolic blood pressures and upper extremity surface temperature changes) were recorded before and 5 min after during the first, fifth and tenth SGB procedures. Results: SGB induced an increase in skin temperature in the ipsilateral hand and persistent dilatation of the radial diameter accompanied by reduction of RI and PI in the radial and third digital arteries in all patients. Conclusion: Hemodynamic changes assessed by spectral Doppler parameters could be used as sensitive and objective measurements of peripheral sympathetic nervous activity and vascular tonus, and may confirm a successfully performed SGB.

scholarly journals Triplex Doppler evaluation of the testes in dogs of different sizes

2014 ◽  
Vol 34 (11) ◽  
pp. 1135-1140 ◽  
Author(s):  
Mírley B. Souza ◽  
Antônio C. Mota Filho ◽  
Carmen V.S. Sousa ◽  
Cynthia L.B. Monteiro ◽  
Gabriela G. Carvalho ◽  
...  
Keyword(s):  
Spermatic Cord ◽  
Resistance Index ◽  
Peak Systolic Velocity ◽  
Doppler Velocimetry ◽  
Diastolic Velocity ◽  
Spectral Doppler ◽  
The Mean ◽  
Doppler Evaluation ◽  
The Right ◽  
Large Groups

This study aimed to assess whether there are differences in Doppler velocimetry parameters between different sizes. Twenty dogs were equally divided into small and large groups used in this study. The dogs were evaluated using Triplex ultrasound. Testicular artery was located by Colour Doppler in the spermatic cord, marginal to the testes and intratesticular segments and then, spectral Doppler were used to calculate: peak systolic velocity (PSV), end diastolic velocity (EDV), resistance index (RI) and pulsatility index (PI). The mean testicular volume in the left side was significantly higher than the right side, in both groups. Doppler examination showed higher velocities (EDV) at spermatic cord in large dogs; marginal to the testes was observed higher velocities in small dogs; intratesticular region no differences were observed (P < 0.05) and within the groups differences between segments of the artery were also observed for each parameter. The results showed that there are differences in Doppler velocimetry parameters between different sizes.

scholarly journals Post-exercise pulsatility index indicates treatment effects in peripheral arterial occlusive disease (PAOD)

2021 ◽  
Author(s):  
Andrej Udelnow ◽  
Maria Hawemann ◽  
Ivo Buschmann ◽  
Frank Meyer ◽  
Zuhir Halloul
Keyword(s):  
Repeated Measures ◽  
Pulsatility Index ◽  
Treatment Effects ◽  
Resistance Index ◽  
Peak Systolic Velocity ◽  
Arterial Tree ◽  
Post Exercise ◽  
Diastolic Velocity ◽  
Before And After ◽  
Healthy Persons

Summary Background Hypothesis: Post-exercise measurements better discriminate PAOD-patients from healthy persons and they more sensitively detect hemodynamic improvements after treatment procedures than resting measurements. Methods A total of 19 healthy volunteers and 23 consecutive PAOD-patients underwent measurements of peak systolic velocity (PSV), end-diastolic velocity (EDV), minimal diastolic velocity (MDV), time-averaged maximum velocities (TAMAX), resistance index (RI) and pulsatility index (PI) before and after a standard exercise test (at 1, 2, 3, 4 and 5 min) before and after treatment (incl. epidemiological data, PAOD risk factors and comorbidities). Results In resting values, healthy persons and PAOD-patients did not differ significantly in any of the hemodynamic parameters. PSV increased after treatment in PAOD-patients by 5 cm/s (paired t‑test, p: 0.025); however, when the amplitude of autoregulatory changes related to the resting values were calculated, PAOD-patients showed clearly less hemodynamic changes after exercise than healthy persons (p: 0.04; 0.002; <0.001 for PSV, TAMAX and PI, resp.). The time course after exercise was compared by repeated measures of ANOVA. Healthy persons differed significantly in PI, RI and PSV from PAOD patients before and after treatment (p<0.001 each). The PAOD-patients revealed a significantly improved PI after treatment (p: 0.042). The only factor contributing significantly to PI independently from grouping was direct arterial vascularization as compared to discontinuous effects by an obstructed arterial tree. Conclusion Healthy persons cannot be well differentiated from PAOD-patients solely by hemodynamics at rest but by characteristic changes after standard exercise. Treatment effects are reflected by higher PI-values after exercise.

scholarly journals Doppler Flow Velocity Indices (RI, PI, S/D & PSV) of Fetal Middle Cerebral Artery in Normal Pregnancies: Correlation with Gestational Age of 20 to 40 Weeks

2012 ◽  
Vol 2 (2) ◽  
pp. 77-80
Author(s):  
Md Abu Taher ◽  
Nuzhat Tasmin ◽  
AS Mohiuddin ◽  
Md Mohit Ul Alam ◽  
Md Mofazzal Sharif ◽  
...  
Keyword(s):  
Middle Cerebral Artery ◽  
Flow Velocity ◽  
Cerebral Artery ◽  
Gestational Age ◽  
Resistance Index ◽  
Peak Systolic Velocity ◽  
Doppler Flow ◽  
Significant Difference ◽  
Before And After ◽  
Doppler Indices

This observational type of descriptive study was carried out in the Department of Radiology and Imaging, BIRDEM selecting 70 Bangladeshi pregnant babies with the aim to find out the normogram of foetal middle cerebral artery Doppler flow velocity indices and correlation between Doppler flow velocity indices [Resistance Index (RI), Pulsatility Index (PI), Systolic/Diastolic ratio (S/D) & Peak Systolic Velocity (PSV)] of foetal middle cerebral artery and gestational age in normal pregnancies of 20 to 40 weeks. It was observed that RI, PI and S/D were decreased with the advance of gestational age but PSV was increases with the advance of gestational age. Statistical analyses showed there were significant difference between mean PSV, RI and PI before and after 25 weeks of gestation. No significant difference was found between mean S/D before and after 25 weeks of gestation. It was observed from Correlation analysis between Doppler indices with independent gestational age that all the Doppler indices of foetal middle cerebra artery was positively correlated with the whole gestation period. The statistical analysis showed only PSV and RI were significantly correlated with the gestational age. Simple regression analysis between dependent Doppler index with independent gestational age before and after 25 weeks revealed that all the Doppler indices had positive relationship with the corresponding gestational age but relationship between PSV and PI (before 25 weeks) with their corresponding gestational ages were only statistically significant.DOI: http://dx.doi.org/10.3329/birdem.v2i2.12306 Birdem Med J 2012; 2(2) 77-80

scholarly journals Levels of agreement in the measurements of carotid artery ultrasound across a regional vascular network

Ultrasound ◽  
2018 ◽  
Vol 26 (2) ◽  
pp. 101-109 ◽  
Author(s):  
Mervyn Alexander McKenna ◽  
Michelle Clare Bonfield ◽  
Teresa Robinson
Keyword(s):  
Carotid Artery ◽  
Internal Carotid Artery ◽  
Common Carotid Artery ◽  
Internal Carotid ◽  
Carotid Artery Disease ◽  
Imaging Modality ◽  
Peak Systolic Velocity ◽  
Vascular Network ◽  
Diastolic Velocity ◽  
Spectral Doppler

Introduction Duplex ultrasound is often the sole imaging modality used in diagnosing carotid artery disease. However, the reproducibility and repeatability of scientists in determining the peak systolic velocity and end diastolic velocity of the internal carotid artery and common carotid artery (CCA) is widely debated. Study aim To investigate intra- and inter-operator variability in diagnostic ultrasound of the carotid arteries across a centralised vascular network using a healthy test subject. To identify potential causes of variability and highlight areas for improvement. Methods Fifteen vascular scientists across four hospital Trusts in the Bristol, Bath and Weston vascular network measured the peak systolic velocity and end diastolic velocity of the internal carotid artery and common carotid artery in a subject using a single portable ultrasound machine. A double blind assessment of spectral Doppler images was performed by two vascular clinical scientists for optimal caliper placement, spectral gain and angle correction. Results were compared for intra- and inter-operator variability. Results Initial quality assessment of the Doppler images revealed that three out of 15 scientists produced suboptimal results. Box plot analysis of the common carotid artery and internal carotid artery for each scientist revealed significant variance (ANOVA p < 0.05). However, a Levene’s test revealed no single operator who consistently produced highly variable results ( p = 0.569). Conclusion This study highlights the difficulty in obtaining consistent velocity measurements from a subject. Despite the variability in absolute peak systolic velocity and end diastolic velocity, scientists were generally consistent in obtaining an optimal spectral Doppler trace. Some issues with consistency were, however, identified which were subsequently addressed.

scholarly journals Role of Duplex Color Doppler Study of Uterine Artery in the Early Diagnosis of Preeclampsia in Pregnant Women

2019 ◽  
Vol 20 (2) ◽  
pp. 87-91
Author(s):  
Sohely Sultana ◽  
Tarana Yasmin ◽  
Md Nazir Uddin Mollah ◽  
Shyamal Kumar Roy ◽  
Mohammad Sazzad Hossain ◽  
...  
Keyword(s):  
Complex Disease ◽  
Color Doppler ◽  
Peak Systolic Velocity ◽  
Resistive Index ◽  
Wave Form ◽  
College Hospital ◽  
Doppler Study ◽  
Diastolic Velocity ◽  
Significant Difference ◽  
Doppler Indices

Background: Duplex Colour Doppler Sonography is gaining increasing popularity for assessment of blood vessels in various disease processes around the world as well as for the surveillance of fetus compromised by intra uterine growth retardation (IUGR) and to assess foetal structural abnormalities and complex disease processes. Materials & methods: This cross sectional study was carried out to observe Doppler wave form in subjects with preeclampsia enrolling 40 subjects with preeclampsia, in the Department of Radiology and Imaging, Dhaka Medical College Hospital, Dhaka, over a period of six months from 20th May 2012 to 19th November 2012. A total number of 40 normal pregnancies were also included for comparison. Peak systolic velocity (PSV), end diastolic velocity (EDV), Resistive index (RI), Pulsatility index (PI) in different groups of study subjects from 24th to 37th weeks were observed and compared for any significant differences. Results: Majority (35% in normal and 37.5% in preeclampsia) of the respondents were found in the age group of 21-30 years. Unpaired t-test revealed no significant difference between mean age between two groups. Among normal group, mean±SD PSV, EDV, PI and RI were 43.94±15.41 cm/sec and 15.51 (±4.93) cm/sec, 1.12±0.0846 and 0.571 (±0.058) respectively. Mean PSV, EDV, PI and RI were 83.19±18.44 cm/sec, 11.86±5.19 cm/sec, 2.497±0.369 and 0.8255±0.087 in preeclampsia group. There was statistically significant (By unpaired ttest) difference in mean Doppler indices between these two groups. It was observed that early diastolic notch was found in 90% subjects with preeclampsia. Early diastolic notch was observed in Doppler wave form in 5% subject with normal pregnancy. Chi-square test showed that there was statistically significant difference in presence of early diastolic notch between normal subjects and subjects with preeclampsia. Conclusions: From the study result it was concluded that Doppler indices with presence of early diastolic notch are reliable indicators for early detection of preeclampsia. J MEDICINE JUL 2019; 20 (2) : 87-91

Spectral analysis of femoral artery blood flow waveforms of conscious domestic cats

2014 ◽  
Vol 16 (12) ◽  
pp. 972-978 ◽  
Author(s):  
Gisele FM dos Reis ◽  
Rodrigo B Nogueira ◽  
Adriana C Silva ◽  
Guilherme Oberlender ◽  
Ruthnéa AL Muzzi ◽  
...  
Keyword(s):  
Blood Flow ◽  
Femoral Artery ◽  
Resistive Index ◽  
Artery Blood Flow ◽  
Domestic Cats ◽  
Mean Velocity ◽  
Diastolic Velocity ◽  
Femoral Artery Blood Flow ◽  
Velocity Peak ◽  
Spectral Doppler

The qualitative and quantitative aspects of femoral artery blood flow waveform spectra were evaluated in 15 male and 15 female Persian and mixed breed domestic cats ( Felis catus), which were healthy and not sedated, using duplex Doppler ultrasonography (DDU). Spectral Doppler demonstrated a biphasic characteristic in 16 (53.34%) of the animals evaluated, and a triphasic characteristic in the 14 (46.66%) remaining animals. The systolic blood pressure and heart rate values were within the normal range for the species. The quantitative parameters evaluated, based on the spectral Doppler, were as follows: systolic velocity peak (SVP), recent diastolic velocity peak (RDVP), end diastolic velocity peak (EDVP), mean velocity (MV), integral velocity time (ITV), artery diameter (AD), femoral flow volume (FFV), pulsatility index (PI), resistive index (RI), systolic peak acceleration time (AT) and deceleration time (DT). The respective mean values were: 36.41 ± 7.33 cm/s, 4.69 ± 0.90 cm/s, 10.74 ± 2.74 cm/s, 23.06 ± 4.86 cm/s, 3.91 ± 1.05 cm, 0.17 ± 0.04 cm, 0.11 ± 0.08 cm3, 3.85 ± 0.19, 1.40 ± 0.20, 39.84 ± 7.38 ms, and 114.0 ± 22.15 ms. No significant differences were found between males and females. The analyses carried out on the femoral artery flow spectrum obtained by DDU showed that it is easy to use and highly tolerated in non-sedated, healthy cats. It appears that DDU may be a useful diagnostic technique, but further studies are needed to evaluate how it compares with invasive telemetric methodology or high-definition oscillometric waveform analytic techniques.

scholarly journals A blood-mimicking fluid with cholesterol as scatter particles for wall-less carotid artery phantom applications

2021 ◽  
Vol 21 (86) ◽  
pp. e219-e224
Author(s):  
Kyermang Kyense Dakok ◽  
◽  
Mohammed Zubir Matjafri ◽  
Nursakinah Suardi ◽  
Ammar Anwar Oglat ◽  
...  
Keyword(s):  
Carotid Artery ◽  
Physical Properties ◽  
Peak Systolic Velocity ◽  
Artery Wall ◽  
Mean Velocity ◽  
Polystyrene Microsphere ◽  
Carotid Artery Wall ◽  
Diastolic Velocity ◽  
Frequency Peak ◽  
Ultrasound Applications

Aim of the study: At present, there are few scatter particles used in preparing blood-mimicking fluids, such as nylon, sephadex, polystyrene microsphere, and poly(4-methystyrene). In this study, we present cholesterol as a new scatter particle for blood-mimicking fluid preparation. Materials and methods: The procedure for the preparation of the proposed blood-mimicking fluid involved the use of propylene glycol, D(+)-Glucose and distilled water to form a ternary mixture fluid, with cholesterol used as scatter particles. Polyethylene glycol was first used as part of the mixture fluid but the acoustic and physical properties were not suitable, leading to its replacement with D(+)-Glucose, which is soluble in water and has a higher density. A common carotid artery wall-less phantom was also produced to assess the flow properties. Results: The prepared blood-mimicking fluid with new scatter particles has a density of 1.067 g/cm3, viscosity of 4.1 mPa.s, speed of sound 1600 m/s, and attenuation of 0.192 dB/cm at 5 MHz frequency. Peak systolic velocity, end diastolic velocity and mean velocity measurements were gotten to be 40.2 ± 2.4 cm/s, 9.9 ± 1.4 cm/s, and 24.0 ± 1.8 cm/s, respectively. Conclusion: Based on the results obtained, the blood-mimicking fluid was found suitable for ultrasound applications in carotid artery wall-less phantoms because of its good acoustic and physical properties.

PROSPECTIVE STUDY OF ALTERATION IN TESTICULAR PERFUSION AND VOLUME IN LAPAROSCOPIC TOTALLY EXTRAPERITONEAL HERNIA REPAIR

2021 ◽  
pp. 122-124
Author(s):  
Sajad Hussain Malik ◽  
Ferkhand Mohi Ud Din ◽  
Hanief Mohammad Dar ◽  
Irshad Ahmad Kumar
Keyword(s):  
Inguinal Hernia ◽  
Hernia Repair ◽  
Prospective Study ◽  
Tertiary Care ◽  
Resistance Index ◽  
Peak Systolic Velocity ◽  
Testicular Volume ◽  
Care Hospital ◽  
Diastolic Velocity ◽  
Testicular Perfusion

PURPOSE:- The objective of this study was to assess the effect of Totally extra-peritoneal inguinal hernia repair on testicular perfusion and testicular volume. METHODS: - After obtaining ethical clearance from institutional ethical committee, the present Prospective study was conducted on 48 male patients with unilateral inguinal hernia in a tertiary care hospital. RESULTS: - The study was conducted on 48 patients over a period of 2 years from august 2017 to august 2019 after meeting inclusion and exclusion criteria. Their mean age was 45.70 years (range 21-72 years). In our study comparison of preoperative and postoperative values at third and sixth month in the patients did not show any statistically signicant alteration in the variables studied like testicular volume (p-0.987) and blood ow perfusion parameters Peak systolic velocity (p-0.591); End Diastolic velocity (p-0.526); Resistance index (p-0.415). CONCLUSION: - No alteration in testicular volume and arterial ow over a six-month period was observed among patients who underwent laparoscopic extra-peritoneal surgical correction using polypropylene prosthesis for inguinal hernia

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