scholarly journals Are pregnancy outcomes associated with risk factor reporting in routinely collected perinatal data?

2013 ◽  
Vol 24 (2) ◽  
pp. 65 ◽  
Author(s):  
Amanda J. Ampt ◽  
Jane B. Ford ◽  
Lee K. Taylor ◽  
Christine L. Roberts
Lupus ◽  
2017 ◽  
Vol 26 (9) ◽  
pp. 983-988 ◽  
Author(s):  
J O Latino ◽  
S Udry ◽  
F M Aranda ◽  
S D A Perés Wingeyer ◽  
D S Fernández Romero ◽  
...  

Conventional treatment of obstetric antiphospholipid syndrome fails in approximately 20–30% of pregnant women without any clearly identified risk factor. It is important to identify risk factors that are associated with these treatment failures. This study aimed to assess the impact of risk factors on pregnancy outcomes in women with obstetric antiphospholipid syndrome treated with conventional treatment. We carefully retrospectively selected 106 pregnancies in women with obstetric antiphospholipid syndrome treated with heparin + aspirin. Pregnancy outcomes were evaluated according to the following associated risk factors: triple positivity profile, double positivity profile, single positivity profile, history of thrombosis, autoimmune disease, more than four pregnancy losses, and high titers of anticardiolipin antibodies and/or anti-βeta-2-glycoprotein-I (aβ2GPI) antibodies. To establish the association between pregnancy outcomes and risk factors, a single binary logistic regressions analysis was performed. Risk factors associated with pregnancy loss with conventional treatment were: the presence of triple positivity (OR = 5.0, CI = 1.4–16.9, p = 0.01), high titers of aβ2GPI (OR = 4.4, CI = 1.2–16.1, p = 0.023) and a history of more than four pregnancy losses (OR = 3.5, CI = 1.2–10.0, p = 0.018). The presence of triple positivity was an independent risk factor associated with gestational complications (OR = 4.1, CI = 1.2–13.9, p = 0.02). Our findings reinforce the idea that triple positivity is a categorical risk factor for poor response to conventional treatment.


Odontology ◽  
2011 ◽  
Vol 100 (2) ◽  
pp. 232-240 ◽  
Author(s):  
Stefano Corbella ◽  
Silvio Taschieri ◽  
Luca Francetti ◽  
Francesca De Siena ◽  
Massimo Del Fabbro

2007 ◽  
Vol 0 (0) ◽  
pp. 071127132039003-??? ◽  
Author(s):  
Anna Agueda ◽  
Josep Ma Ramón ◽  
Carolina Manau ◽  
Adrian Guerrero ◽  
José J. Echeverría

2017 ◽  
Vol 2017 ◽  
pp. 1-7 ◽  
Author(s):  
Jing Yang ◽  
Yan Wang ◽  
Xiao-ye Wang ◽  
Yan-yu Zhao ◽  
Jing Wang ◽  
...  

Although a history of first-trimester recurrent spontaneous abortion (FRSA) is regarded as a risk factor in antenatal care, the characteristic of subsequent pregnancy outcome is not clearly elucidated. Here, a retrospective analysis was performed on the clinical data of 492 singleton pregnant women. 164 of them with the history of FRSA were enrolled in study group, compared to 328 deliveries without the history of FRSA. For maternal outcomes, patients in the study group delivered earlier with mean gestational age and the incidences of cesarean section and postpartum hemorrhage were higher compared to the control group. For placental outcomes, the incidence of placenta-mediated pregnancy complications (PMPC) in the study group increased in terms of late-onset preeclampsia, oligohydramnios, early-onset fetal growth restriction, and second-trimester abortion. Patients in the study group were more likely to suffer from placenta accreta, placenta increta, and placenta percreta. For perinatal outcomes, the proportion of birth defects of newborns in the study group was greater. At last, logistic regression analyses showed that the history of FRSA was an independent risk factor for cesarean section and pregnancy complications. In conclusion, women with the history of FRSA are often exposed to an elevated incidence of maternal-placental-perinatal adverse pregnancy outcomes.


2011 ◽  
Vol 29 (04) ◽  
pp. 277-282 ◽  
Author(s):  
Francesca Facco ◽  
Cici Liu ◽  
Andrea Cabello ◽  
Ashley Kick ◽  
William Grobman ◽  
...  

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