The obstetrician, congenital cytomegalovirus, clinical and diagnostic approaches to the pregnant woman

2015 ◽  
Vol 36 (4) ◽  
pp. 194
Author(s):  
Antonia W Shand
Keyword(s):  
Magnetic Resonance Imaging ◽  
Pregnant Woman ◽  
Fetal Mri ◽  
Maternal Infection ◽  
Resonance Imaging ◽  
Cmv Infection ◽  
Serological Screening ◽  
Congenital Cytomegalovirus ◽  
Fetal Infection ◽  
Diagnostic Approaches

There is low awareness of congenital cytomegalovirus (CMV) in Australia. Routine pregnancy serological screening for CMV is not recommended, but all pregnant women should be given advice about CMV prevention. Obstetricians may be asked to see a pregnant woman when serology suggests CMV infection or when features of fetal infection are present on ultrasound. If maternal CMV infection is confirmed, the timing of infection (pre-pregnancy or gestation of pregnancy), must be determined to predict the fetal risks. In addition, it is important to establish whether maternal infection is primary or reactivation. If there is fetal infection, ultrasound can be used to attempt to establish whether the fetus may have been affected. Serial serology, CMV IgG avidity, maternal viraemia (using serum PCR), amniotic fluid CMV PCR, serial fetal ultrasounds, and possibly fetal MRI (magnetic resonance imaging) are investigations that may be useful to predict neonatal outcomes. Timely and accurate counselling is important to optimise maternal and neonatal management.

Severe fetal anaemia caused by congenital cytomegalovirus infection

2021 ◽  
Vol 14 (10) ◽  
pp. e244585
Author(s):  
Claudia Salazar-Sanchez ◽  
Pedro Llancarí ◽  
Rommy H Novoa ◽  
Walter Ventura
Keyword(s):  
Pregnant Woman ◽  
Fetal Growth ◽  
Umbilical Cord Blood ◽  
Cytomegalovirus Infection ◽  
Peak Systolic Velocity ◽  
Cmv Infection ◽  
Congenital Cytomegalovirus Infection ◽  
Congenital Cytomegalovirus ◽  
Fetal Medicine ◽  
Fetal Infection

A 22-year-old pregnant woman was referred to our fetal medicine unit due to severe fetal growth restriction at 26 weeks of gestation. An extensive detailed ultrasound revealed signs of bilateral periventricular hyperechogenicity, suggesting fetal infection potentially due to cytomegalovirus (CMV). Doppler ultrasound showed a high peak systolic velocity in the middle cerebral artery. Percutaneous umbilical cord blood sampling confirmed fetal CMV infection and severe fetal anaemia. We present this case to highlight the importance of fetal anaemia, which can be fatal regardless of whether it is associated with generalised oedema or hydrops fetalis.

scholarly journals Use of Magnetic Resonance Imaging in Evaluating Fetal Brain and Abdomen Malformations during Pregnancy

Medicina ◽  
2019 ◽  
Vol 55 (2) ◽  
pp. 55 ◽  
Author(s):  
Nomeda Valevičienė ◽  
Guoda Varytė ◽  
Jolita Zakarevičienė ◽  
Eglė Kontrimavičiūtė ◽  
Diana Ramašauskaitė ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Fetal Brain ◽  
Fetal Mri ◽  
University Hospital ◽  
Resonance Imaging ◽  
Internal Organs ◽  
Intravenous Contrast ◽  
Vilnius University ◽  
Magnetic Resonance Imaging Mri

Magnetic resonance imaging (MRI) is used as a clarifying technique after a high-resolution ultrasound examination during pregnancy. Combining ultrasound with MRI, additional diagnostic information is obtained or ultrasound diagnosis is frequently corrected. High spatial resolution provides accurate radiological imaging of internal organs and widens possibilities for detecting perinatal development disorders. The safety of MRI and the use of intravenous contrast agent gadolinium are discussed in this article. There is no currently available evidence that MRI is harmful to the fetus, although not enough research has been carried out to prove enduring safety. MRI should be performed when the benefit outweighs the potential side effects. The narrative review includes several clinical cases of fetal MRI performed in Vilnius University Hospital Santaros Clinics.

scholarly journals Prediction of the Outcome of Cochlear Implantation in the Patients with Congenital Cytomegalovirus Infection based on Magnetic Resonance Imaging Characteristics

2019 ◽  
Vol 8 (2) ◽  
pp. 136
Author(s):  
Jae Han ◽  
Yun Bae ◽  
Seul Song ◽  
Jae-Jin Song ◽  
Ja-Won Koo ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Cochlear Implantation ◽  
Brain Mri ◽  
Brain Magnetic Resonance Imaging ◽  
Control Group ◽  
Resonance Imaging ◽  
Mri Findings ◽  
Congenital Cytomegalovirus ◽  
Imaging Characteristics

The goal of this study was to elucidate radiologic biomarker that can predict the outcome of cochlear implantation (CI) in congenital cytomegalovirus (cCMV) related deafness. A retrospective survey of speech perception after CI and an evaluation of brain magnetic resonance imaging (MRI) findings were performed in 10 cochlear implantees with cCMV-related prelingual deafness. Specifically, a special attention was paid to the degree of white matter (WM) abnormality shown in brain MRI, which was used to divide our cohort into two groups: The mild and severe pathology groups. Age-matched prelingual deaf patients with idiopathic sensorineural hearing loss were selected as controls. Subjects in mild pathology groups showed higher a Category of Auditory Performance (CAP) score (5.2 ± 0.8) than those with severe pathologies (3.4 ± 1.5) (P = 0.041). Importantly, speech performance from subjects with mild pathology was comparable to that of the control group (mean CAP score of 5.2 ± 0.8 vs. 5.1 ± 1.2) (P = 0.898). Mild pathologies related to the limited WM lesion in MRI not accompanied by severe MRI pathologies, such as diffuse WM abnormality, myelination delay, ventriculomegaly, migration abnormality, and cerebellar hypoplasia, can be tolerated and do not adversely affect the CI outcome in cCMV deafness.

scholarly journals Association of Progesterone, Pessary, and Antibiotic for Treating Pregnant Woman with Short Cervix Syndrome: Importance of Magnetic Resonance Imaging in the Assessment of Pessary Position

2013 ◽  
Vol 3 ◽  
pp. 27 ◽  
Author(s):  
Edward Araujo Júnior ◽  
Eduardo Félix Martins Santana ◽  
Luciano Marcondes Machado Nardozza ◽  
Antonio Fernandes Moron
Keyword(s):  
Magnetic Resonance Imaging ◽  
Case Report ◽  
Pregnant Woman ◽  
Magnetic Resonance ◽  
Antibiotic Therapy ◽  
Triple Therapy ◽  
Resonance Imaging ◽  
Trendelenburg Position ◽  
Short Cervix ◽  
Cervical Gland

Preterm delivery (PD) is the most important cause of neonatal mortality, particularly before the 32nd week of pregnancy. A short cervix is the most important quantitative marker for predicting PD. However, there are other qualitative markers such as cervical gland area, cervical funneling, and sludge. We present the case of a pregnant woman who was diagnosed with a short cervix at 14-weeks and demonstrate the use of triple therapy, which helped to achieve a good perinatal result. A 37-year-old pregnant woman (G3P0) was referred to our service at 14-weeks of pregnancy presenting with a short cervix (20 mm) and a positive sludge sign. She was hospitalized; a pessary was inserted, and started on antibiotic therapy (clindamycin and cefalotin for 10 days). At 20 weeks, she was again admitted to the hospital, and this time presented with a further shortened cervix (9 mm), cervical funneling, and a positive sludge sign, with the pessary in position. The following procedures were performed: Amniocentesis on the sludge (negative bacterioscopy), another cycle of antibiotics, administration of oral progesterone, and imaging to determine retention of pessary position. The patient was placed in the Trendelenburg position and remained hospitalized for 82 days. At 32 + 1 weeks, the fetus presented distress (tachycardia). C-section was performed, producing a live female newborn weighing 2,180 g and presenting Apgar indexes of 8/8. This case report demonstrates the importance of magnetic resonance imaging to assess the position of pessary in a pregnant woman with short cervix.

scholarly journals Myomectomy scar pregnancy: a case report and review of the literature

2020 ◽  
Vol 48 (7) ◽  
pp. 030006052092454
Author(s):  
Linling Zhu ◽  
Xinyun Yang ◽  
Wenchao Sun ◽  
Liang Qian ◽  
Songyi Li ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Case Report ◽  
Pregnant Woman ◽  
Vaginal Bleeding ◽  
Late Complication ◽  
Uterine Fibroids ◽  
Review Of The Literature ◽  
Resonance Imaging ◽  
Postoperative Course ◽  
Gestational Sac

Myomectomy scar pregnancy (MSP) is a rare disease, which is defined as a gestational sac located within a previous myomectomy scar. MSP is an uncommon late complication of uterine fibroids after myomectomy. We report a case where the implantation site matched the site of the previous myomectomy, and review the existing literature. A 28-year-old pregnant woman presented with vaginal bleeding. She was diagnosed with MSP by ultrasound and magnetic resonance imaging, and then underwent laparotomic enucleation. The patient’s postoperative course was uneventful. Taking into account the findings in our case and the seven other reported cases of MSP, we propose that MSP can be divided into three types and that surgical enucleation of the pregnancy mass is an effective treatment.

scholarly journals Schizencephaly on fetal MRI

2008 ◽  
Vol 12 (3) ◽  
pp. 77
Author(s):  
S Reddy ◽  
E Rudakemwa ◽  
M Modi
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Grey Matter ◽  
Fetal Mri ◽  
Prenatal Ultrasound ◽  
Spinal Fluid ◽  
Full Thickness ◽  
Resonance Imaging ◽  
Magnetic Resonance Imaging Mri ◽  
Cns Malformation

Schizencephaly is a rare CNS malformation consisting of a full-thickness CSF filled parenchymal cleft lined by grey matter (3). Schizencephaly can be diagnosed on prenatal ultrasound but requires magnetic resonance imaging (MRI) for more specific diagnostic differentiation from other cerebro-spinal fluid (CSF) containing structures as well as for detection of associated features (3).

scholarly journals Brain Magnetic Resonance Imaging in Congenital Cytomegalovirus With Failed Newborn Hearing Screen

2020 ◽  
Vol 110 ◽  
pp. 55-58
Author(s):  
Jennifer A. Hranilovich ◽  
Albert H. Park ◽  
Elizabeth D. Knackstedt ◽  
Betsy E. Ostrander ◽  
Gary L. Hedlund ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Brain Magnetic Resonance Imaging ◽  
Resonance Imaging ◽  
Congenital Cytomegalovirus ◽  
Newborn Hearing
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