scholarly journals Respiratory infections in the newborn

2008 ◽  
Vol 29 (4) ◽  
pp. 197
Author(s):  
Michael D Nissen ◽  
Theo Sloots

It is well recognised that acute respiratory tract infection (ARTI) occurs commonly in children younger than 5 years of age, with pneumonia being the most serious complication. The greatest risk of death from pneumonia in childhood is in the neonatal period; it is estimated that pneumonia contributes to between 0.75-1.2 million neonatal deaths annually, accounting for approximately 10% of global child mortality. Of all neonatal deaths due to pneumonia, 96% occur in the developing world.

2013 ◽  
Vol 9 (3) ◽  
pp. 97
Author(s):  
Abdullah Abdullah ◽  
Endy Paryanto Prawirohartono ◽  
Siti Helmyati

Background: Vitamin A deficiency is a nutritional problem in infants since breastmilk insufficiently contains vitamin A. Therefore it is necessary to study the effect of vitamin A supplementation to mothers at parturition period on growth and morbidities of infants at 0-4 months of age.Objective: To identify the effect of vitamin A supplementation to mothers at parturition period on growth and morbidities of infants at 0-4 months of age.Method: We conducted a randomized controlled trial from March-July 2009 at Province of Lampung. We recruited 90 mothers that were grouped into vitamin A supplementation group and socialization about vitamin A group during parturition period. The outcomes of this study were growth in WHZ and morbidities of infants at 0-4 months of age measured as duration of acute diarrhea and upper respiratory infections. Statistical analysis was performed by using Chi-Square and t-test.Results: The growth of infants of 0-4 months from vitamin A supplemented mothers was not significantly different from the socialization group. Duration of diarrhea and acute respiratory tract infection of infants from supplemented mothers at parturition period was significantly shorter than of infants from socialization group.Conclusion: The growth of infant at 0-4 months of age from vitamin A supplemented mothers at parturition period were not significantly different from those who were from education group. Duration of diarrhea and acute respiratory tract infection of infants from vitamin A supplemented mothers at parturition period were shorter than those who were from education group.


2020 ◽  
Vol 7 (Supplement_1) ◽  
pp. S395-S395
Author(s):  
Joyce Appiah-Kubi

Abstract Background Acute respiratory tract infections of viral origin remain a leading cause of morbidity, mortality and economic loss regardless of age or gender. A small number of acute respiratory tract infection cases caused by enterovirus D68 (EV-D68) have been reported regularly to Centers for Disease Control and Prevention since 1987 by countries in North America, Europe and Asia. However, in 2014 and 2015, the number of reported confirmed EV-D68 infections was much greater than in previous years. The National Influenza Centre (NIC), Ghana carries out surveillance of respiratory infections, focusing on those caused by influenza virus; however, there is inadequate information on other viruses causing respiratory infections in Ghana, including EV-D68. Objectives To investigate the association of EV-D68 with Severe Acute Respiratory Infections (SARI) and Influenza-Like Illness (ILI) in Ghana. Methods This was a retrospective cross-sectional study which involved archived human respiratory specimens stored at -80ºC at the NIC from 2014 to 2015. Using a random sampling method, oropharyngeal and nasopharyngeal swabs from patients with SARI and ILI that were negative by real-time PCR for human influenza viruses were screened for EV-D68 using real-time reverse transcription-polymerase chain reaction (rRT-PCR). Results Enterovirus D68 was detected in 4 (2.2%) out 182 SARI samples tested. EV-D68 was detected in children younger than 5 years (4-100% of positives) and was not detected in children older than 5 years. Enterovirus D68 was detected more frequently in SARI cases (3%) than in ILI cases (1.2%). Conclusion This study has shown for the first time the presence of EV-D68 in acute respiratory infection in Ghana. The results confirmed minimal EV-D68 circulation in the Ghanaian population. Disclosures All Authors: No reported disclosures


1994 ◽  
Vol 10 (1) ◽  
pp. 57-61 ◽  
Author(s):  
R. Biswas ◽  
A. B. Biswas ◽  
B. Manna ◽  
S. K. Bhattacharya ◽  
R. Dey ◽  
...  

PeerJ ◽  
2017 ◽  
Vol 5 ◽  
pp. e3970 ◽  
Author(s):  
Ilada Thongpan ◽  
John Mauleekoonphairoj ◽  
Preeyaporn Vichiwattana ◽  
Sumeth Korkong ◽  
Rujipat Wasitthankasem ◽  
...  

Respiratory syncytial virus (RSV) causes acute lower respiratory tract infection in infants and young children worldwide. To investigate the RSV burden in Thailand over four consecutive years (January 2012 to December 2015), we screened 3,306 samples obtained from children ≤5 years old with acute respiratory tract infection using semi-nested reverse-transcription polymerase chain reaction (RT-PCR). In all, 8.4% (277/3,306) of the specimens tested positive for RSV, most of which appeared in the rainy months of July to November. We then genotyped RSV by sequencing the G glycoprotein gene and performed phylogenetic analysis to determine the RSV antigenic subgroup. The majority (57.4%, 159/277) of the RSV belonged to subgroup A (RSV-A), of which NA1 genotype was the most common in 2012 while ON1 genotype became prevalent the following year. Among samples tested positive for RSV-B subgroup B (RSV-B) (42.6%, 118/277), most were genotype BA9 (92.6%, 87/94) with some BA10 and BA-C. Predicted amino acid sequence from the partial G region showed highly conserved N-linked glycosylation site at residue N237 among all RSV-A ON1 strains (68/68), and at residues N296 (86/87) and N310 (87/87) among RSV-B BA9 strains. Positive selection of key residues combined with notable sequence variations on the G gene contributed to the continued circulation of this rapidly evolving virus.


2020 ◽  
Vol 7 (11) ◽  
pp. 2198
Author(s):  
Rajesh Kumar Sah ◽  
Hemant Kumar

Background: Acute respiratory tract infection are a major cause of global morbidity and mortality. Observational studies report consistent independent association between low serum concentration of 25-hydroxy-vitamin D and susceptibility to acute respiratory tract infection. This study was done to assess serum vitamin D level in children and correlation with respiratory tract infection.Methods: The present study was undertaken in department of paediatrics medicine, Patna Medical College and Hospital in patients attending out-patients department (OPD) as well as admitted in in-patients department (IPD). Assessment of serum 25(OH) Vitamin D was done by the enzyme immunoassay kit at Patna Medical College and Hospital.Results: The mean serum vitamin D level in cases was (20.52±5.64 ng/ml) where as in control group was (26.46±4.52 ng/ml) with a statically significant p value of <0.0001, hence cases are associated with vitamin D deficiency.Conclusions: The finding in this study showed significantly decreased mean serum vitamin D level in cases than that of control which implies that vitamin D deficiency predisposes to respiratory tract infection in children.


2018 ◽  
Vol 90 (5) ◽  
pp. 861-866 ◽  
Author(s):  
Miriam Gómez‐Novo ◽  
José A. Boga ◽  
Marta E. Álvarez‐Argüelles ◽  
Susana Rojo‐Alba ◽  
Ana Fernández ◽  
...  

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