Rodney Warren Rickards 1934 - 2007

2011 ◽  
Vol 22 (2) ◽  
pp. 229 ◽  
Author(s):  
Lewis N. Mander ◽  
Martin A. Bennett
Keyword(s):  
Academic Career ◽  
Antibiotic Production ◽  
Close Association ◽  
Control Cell ◽  
Biomimetic Synthesis ◽  
Active Components ◽  
National University ◽  
Veterinary Importance ◽  
The University

Rod Rickards graduated with first class honours from the University of Sydney in 1955 and began his academic career at the University of Manchester in close association with Arthur Birch. In 1966 he returned to Australia to a foundation appointment in the Research School of Chemistry at the Australian National University, where he spent the remainder of his career. His research was primarily concerned with the organic and biological chemistry of compounds of medical, biological, agricultural and veterinary importance, and was characterized by an integration of organic synthesis, biomimetic synthesis, structural and stereochemical studies, and biosynthetic studies using isotopically labelled precursors in vivo. His interests ranged widely and included antibiotics, regulatory factors that initiate antibiotic production and control cell differentiation and sexuality in microorganisms, elicitors that communicate between bacteria and plants, mammalian hormones of the prostaglandin group that control many aspects of human physiology, juvenile hormones, which mediate the development and reproductive physiology of higher dipteran insects and the therapeutically active components of Cannabis resin.

Raymond John Stalker 1930–2014

2016 ◽  
Vol 27 (1) ◽  
pp. 70 ◽  
Author(s):  
Caroline Stalker ◽  
Richard Morgan ◽  
Roger I. Tanner
Keyword(s):  
Hypersonic Flow ◽  
Academic Career ◽  
The World ◽  
Flow Speeds ◽  
National University ◽  
The University

Raymond John Stalker was born in Dimboola, Victoria on 6 August 1930 and died in Brisbane on 9 February 2014. He had a distinguished academic career at the Australian National University in Canberra and at the University of Queensland. His work on hypersonic flow was universally recognized, and the ‘Stalker Tube' facilities he pioneered were able to reach unprecedented flow speeds and were reproduced in many laboratories around the world.

Some aspects of nutrition in Philophthalmus burrili (Trematoda: Digenea)

Parasitology ◽  
1971 ◽  
Vol 62 (1) ◽  
pp. 133-144 ◽  
Author(s):  
M. J. Howell
Keyword(s):  
Acid Phosphatase ◽  
Ventral Sucker ◽  
Close Association ◽  
Food Material ◽  
Research Scholarship ◽  
National University ◽  
Contact Digestion ◽  
A Site

The effects of P. burrili adults on the chicken host are outlined. There was no evidence that infections of up to 20 flukes caused marked pathological changes in the nictitating membrane to which flukes attach in an intimate 'placental' manner by the ventral sucker.The food material of adult flukes is largely lacrimal secretion; it appears that blood can be excluded from the diet since the caecal contents are colourless and haemoglobin was not detected histochemically. Little material was detected in the caeca by the histochemical techniques used. The presence of a mucus coat around flukes was noted and it is suspected that materials of nutritional significance may be conserved in this coat for long periods. Glucose was demonstrated in the parenchyma surrounding the uterus. It is suggested that this might indicate either (a) polysaccharide degradation in this region; (b) polysaccharide synthesis; or (c) a site of accumulation of glucose which enters through the tegument and caeca. The presence of greatest activity in the uterine region may be indicative of nutritional dependence of the developing miracidium on the parent fluke.The gastrodermis of the caeca is regular, consisting of flattened cells with a very prominent PAS positive, striated border of microvilli. The cytoplasm of the cells contains appreciable amounts of RNA. Protease, acid phosphatase and possibly esterase have been demonstrated in the gastrodermis.Possible esterase activity occurs in the ventral sucker, alkaline phosphatase is present in the lining of the excretory ducts, and acid phosphatase has also been demonstrated in the pharynx, both suckers, and subcuticular region.Ferritin was ingested by flukes in vivo and this enabled the digestion cycle to be followed. Flukes ingested little or no ferritin in vitro. Digestion was completed within 13 h and appeared to take place in close association with the striated border rather than in the lumen. The possibilities are that (a) material is digested intracellularly within the microvilli; (b) membrane (contact) digestion takes place; (c) extracellular digestion, in close association with the striated border, takes place. These processes are not necessarily mutually exclusive.I should like to thank Professor J. D. Smyth for his helpful advice. This study was carried out during the tenure of an Australian National University Research Scholarship.

Lawrence Walter Nichol 1935–2015

2018 ◽  
Vol 29 (1) ◽  
pp. 51 ◽  
Author(s):  
Peter D. Jeffrey ◽  
Donald J. Winzor ◽  
Philip W. Kuchel
Keyword(s):  
New England ◽  
Medical Research ◽  
Academic Career ◽  
Research Fellow ◽  
Vice Chancellor ◽  
National University ◽  
The University ◽  
Physical Biochemistry ◽  
Australian Universities

Lawrence (Laurie) Walter Nichol FAA was Vice Chancellor of the Australian National University (ANU) from 1988 to 1993, and before that, of the University of New England (UNE) from 1985 to 1988. His independent academic career began in 1963 at the ANU as a Research Fellow in the Department of Physical Biochemistry in the John Curtin School of Medical Research (JCSMR). The department was headed by Professor Alexander (Sandy) G. Ogston FRS. Thus, Laurie's career finally circled back, after overseas sabbaticals and other appointments at Australian universities, to the ANU.

Penglibatan Ahli Akademik Terhadap Pengajaran Hadith di Institusi Pengajian

2018 ◽  
pp. 47-52
Author(s):  
Amran Abdul Halim ◽  
Abdulloh Salaeh
Keyword(s):  
Public Universities ◽  
Academic Staff ◽  
Descriptive Analysis ◽  
Good Knowledge ◽  
Islamic Studies ◽  
National University ◽  
Islamic Science ◽  
The University

This study is to identify the involvement of academicians on the teaching of the hadith. The contribution of the academicians to the teaching of the hadith is also very much needed so that Muslims can acknowledge al-Sunnah closely. The academicians were selected from Academic of Islamic Studies, University of Malaya Islamic Studies Academy, the National University of Malaysia, the Islamic Science University of Malaysia and the International Islamic University which they are all from various fields of Islamic Studies. The methodology used in this study is a questionnaire which is group sampling. The researcher distributes the questionnaire to the academic staff at the university involved. Based on this descriptive analysis of the questionnaire, it can be concluded that academic practitioners either in the field of hadith or other fields are involved and contribute to the teaching of hadith such as in public universities and other institutions. This shows that most academicians have good knowledge related to the field of hadith. Therefore, they are among the most suitable as references to the community in solving Sunnah and bidaah issues, especially the academicians who are experts in the field of hadith. Abstrak Kajian ini adalah untuk mengenalpasti penglibatan ahli akademik terhadap pengajaran hadith. Sumbangan ahli akademik terhadap pengajaran hadith juga amat diperlukan agar umat Islam dapat mengenali al-Sunnahsecara  lebih  dekat.  Ahli-ahli  akademik  yang  dipilih  adalah  dari  Akademi  Pengajian  Islam  Universiti Malaya,   Universiti   Kebangsaan   Malaysia,   Universiti   Sains   Islam   Malaysia   dan   Universiti   Islam Antarabangsa  yang  mana  kesemuanya  dalam  pelbagai  bidang  Pengajian  Islam.  Kaedah yang  digunakan dalam kajian ini adalah soal selidik iaitu persampelan berkelompok. Penyelidikmengedarkan borang soal selidik tersebut kepada ahli akademik di universiti tersebut. Berdasarkan, analisis deskriptif soal selidik ini, dapat dirumuskan bahawa ahli akademik sama ada dalam bidang hadith atau lain-lain bidang adalah terlibat dan turut memberi sumbangan dalam pengajaran hadith seperti di universiti-universiti awam dan lain-lain institusi  pengajian.  Ini  menunjukkan  bahawa  kebanyakan  ahli  akademik  mempunyai  pengetahuan  yang baik  berkaitan  dengan  bidang  hadith.  Oleh  itu,  mereka  adalah  antara  golongan  sangat  sesuai  dijadikan sebagai rujukan masyarakat dalam menyelesaikan permasalahan Sunnah dan bidaah, terutama sekali ahli akademik yang pakar dalam bidang hadith.

Factors Influencing Academic Stress on Students of University of Economics and Business - Vietnam National University

2020 ◽  
Vol 36 (3) ◽  
Author(s):  
Nham Phong Tuan ◽  
Nguyen Ngoc Quy ◽  
Nguyen Thi Thanh Huyen ◽  
Hong Tra My ◽  
Tran Nhu Phu
Keyword(s):  
Academic Stress ◽  
Stress Factors ◽  
Negative Effects ◽  
Cross Sectional ◽  
Stress Scale ◽  
Perceptions And Attitudes ◽  
National University ◽  
Questionnaire Surveys ◽  
The University ◽  
The Impact

The objective of this study is to investigate the impact of seven factors causing academic stress on students of University of Economics and Business - Vietnam National University: Lack of leisure time, Academic performance, Fear of failure, Academic overload, Finances, Competition between students, Relationships with university faculty. Based on the results of a practical survey of 185 students who are attending any courses at the University of Economics and Business - Vietnam National University, the study assesses the impact of stress factors on students. The thesis focuses on clarifying the concept of "stress" and the stress level of students, while pointing out its negative effects on students. This study includes two cross-sectional questionnaire surveys. The first survey uses a set of 16 questions to assess students’ perceptions and attitudes based on an instrument to measure academic stress - Educational Stress Scale for Adolescents (ESSA). The second survey aims to test internal consistency, the robustness of the previously established 7-factor structure. Henceforth, the model was brought back and used qualitatively, combined with Cronbach’s Alpha measurement test and EFA discovery factor analysis. This study was conducted from October 2019 to December 2019. From these practical analyzes, several proposals were made for the society, the school and the students themselves.

Chernivtsi National University during the Romanian period in Bukovina’s history (1918-1940)

2017 ◽  
pp. 118-125
Author(s):  
Liubov Melnychuk
Keyword(s):  
Higher Education ◽  
Church And State ◽  
Radical Change ◽  
The State ◽  
Ongoing Training ◽  
State Apparatus ◽  
National University ◽  
The Government ◽  
The University

The author investigates and analyzes the state Chernivtsi National University during the Romanian period in Bukovina’s history. During that period in the field of education was held a radical change in the direction of intensive Romanization. In period of rigid occupation regime in the province, the government of Romania laid its hopes on the University. The Chernivtsi National University had become a hotbed of Romanization ideas, to ongoing training for church and state apparatus, to educate students in the spirit of devotion Romania. Keywords: Chernivtsi National University, Romania, Romanization, higher education, Bukovina

iTSP-PseAAC: Identify Tumor Suppressor Proteins by Using Fully Connected Neural Network and PseAAC

2021 ◽  
Vol 15 ◽  
Author(s):  
Muhammad Awais ◽  
Waqar Hussain ◽  
Nouman Rasool ◽  
Yaser Daanial Khan
Keyword(s):  
Tumor Suppressor ◽  
Cross Validation ◽  
Control Cell ◽  
Normal Function ◽  
In Vivo Studies ◽  
Tumor Suppressor Proteins ◽  
Proposed Model ◽  
Self Consistency

Background: The uncontrolled growth due to accumulation of genetic and epigenetic changes as a result of loss or reduction in the normal function of Tumor Suppressor Genes (TSGs) and Pro-oncogenes is known as cancer. TSGs control cell division and growth by repairing of DNA mistakes during replication and restrict the unwanted proliferation of a cell or activities, those are the part of tumor production. Objectives: This study aims to propose a novel, accurate, user-friendly model to predict tumor suppressor proteins, which would be freely available to experimental molecular biologists to assist them using in vitro and in vivo studies. Methods: The predictor model has used the input feature vector (IFV) calculated from the physicochemical properties of proteins based on FCNN to compute the accuracy, sensitivity, specificity, and MCC. The proposed model was validated against different exhaustive validation techniques i.e. self-consistency and cross-validation. Results: Using self-consistency, the accuracy is 99%, for cross-validation and independent testing has 99.80% and 100% accuracy respectively. The overall accuracy of the proposed model is 99%, sensitivity value 98% and specificity 99% and F1-score was 0.99. Conclusion: It concludes, the proposed model for prediction of the tumor suppressor proteins can predict the tumor suppressor proteins efficiently, but it still has space for improvements in computational ways as the protein sequences may rapidly increase, day by day.

scholarly journals Enamel interproximal reduction during treatment with clear aligners: digital planning versus OrthoCAD analysis

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Giuseppina Laganà ◽  
Arianna Malara ◽  
Roberta Lione ◽  
Carlotta Danesi ◽  
Simonetta Meuli ◽  
...  
Keyword(s):  
Treatment Plan ◽  
End Of Treatment ◽  
The Mean ◽  
The Difference ◽  
Dependent Sample ◽  
University Of Rome ◽  
The University ◽  
Enamel Reduction ◽  
Lower Arch

Abstract Background The aim of the study was to compare the amount of interproximal enamel reduction (IPR) provided on ClinCheck software with the amount of IPR carried out by the orthodontist during treatment with clear aligners. Methods 30 subjects (14 males, 16 females; mean age of 24.53 ± 13.41 years) randomly recruited from the Invisalign account of the Department of Orthodontics at the University of Rome “Tor Vergata” from November 2018 to October 2019, were collected according to the following inclusion criteria: mild to moderate dento-alveolar discrepancy (1.5–6.5 mm); Class I canine and molar relationship; full permanent dentition (excluding third molars); both arches treated only using Comprehensive Package by Invisalign system; treatment plan including IPR. Pre- (T0) and post-treatment (T1) digital models (.stl files), created from an iTero scan, were collected from all selected patients. The OrthoCAD digital software was used to measure tooth mesiodistal width in upper and lower arches before (T0) and at the end of treatment (T1) before any refinement. The widest mesio-distal diameter was measured for each tooth excluding molars by “Diagnostic” OrthoCAD tool. The total amount of IPR performed during treatment was obtained comparing the sum of mesio-distal widths of all measured teeth at T0 and T1. Significant T1–T0 differences were tested with dependent sample t-test (P < 0.05). Results In the upper arch, IPR was digitally planned on average for 0.62 mm while in the lower arch was on average for 1.92 mm. As for the amount of enamel actually removed after IPR performing, it was on average 0.62 mm in the maxillary arch. In the mandibular arch, the mean of IPR carried out was 1.93 mm. The difference between planned IPR and performed IPR is described: this difference was on average 0.00 mm in the upper arch and 0.01 in the lower arch. Conclusions The amount of enamel removed in vivo corresponded with the amount of IPR planned by the Orthodontist using ClinCheck software.

scholarly journals Ferroptosis contributes to isoflurane-induced neurotoxicity and learning and memory impairment

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Pengfei Liu ◽  
Jing Yuan ◽  
Yetong Feng ◽  
Xin Chen ◽  
Guangsuo Wang ◽  
...  
Keyword(s):  
Cell Death ◽  
Learning And Memory ◽  
Memory Impairment ◽  
Close Association ◽  
Dimethyl Fumarate ◽  
Dependent Manner ◽  
Transport Chain ◽  
The Relationship

AbstractFerroptosis is a novel type of programmed cell death, which is different from apoptosis and autophagic cell death. Recently, ferroptosis has been indicated to contribute to the in vitro neurotoxicity induced by isoflurane, which is one of the most common anesthetics in clinic. However, the in vivo position of ferroptosis in isoflurane-induced neurotoxicity as well as learning and memory impairment remains unclear. In this study, we mainly explored the relationship between ferroptosis and isoflurane-induced learning and memory, as well as the therapeutic methods in mouse model. Our results indicated that isoflurane induced the ferroptosis in a dose-dependent and time-dependent manner in hippocampus, the organ related with learning and memory ability. In addition, the activity of cytochrome c oxidase/Complex IV in mitochondrial electron transport chain (ETC) was increased by isoflurane, which might further contributed to cysteine deprivation-induced ferroptosis caused by isoflurane exposure. More importantly, isoflurane-induced ferroptosis could be rescued by both ferroptosis inhibitor (ferrostatin-1) and mitochondria activator (dimethyl fumarate), which also showed effective therapeutic action against isoflurane-induced learning and memory impairment. Taken together, our data indicate the close association among ferroptosis, mitochondria and isoflurane, and provide a novel insight into the therapy mode against isoflurane-induced learning and memory impairment.

scholarly journals Inhibitory Effect of Sargassum fusiforme and Its Components on Replication of Respiratory Syncytial Virus In Vitro and In Vivo

Viruses ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 548
Author(s):  
Kiramage Chathuranga ◽  
Asela Weerawardhana ◽  
Niranjan Dodantenna ◽  
Lakmal Ranathunga ◽  
Won-Kyung Cho ◽  
...  
Keyword(s):  
Respiratory Syncytial Virus ◽  
Antiviral Agent ◽  
Active Components ◽  
Sargassum Fusiforme ◽  
Antiviral Effects ◽  
Improve Life Expectancy ◽  
Rsv Infection ◽  
Syncytial Virus

Sargassum fusiforme, a plant used as a medicine and food, is regarded as a marine vegetable and health supplement to improve life expectancy. Here, we demonstrate that S. fusiforme extract (SFE) has antiviral effects against respiratory syncytial virus (RSV) in vitro and in vivo mouse model. Treatment of HEp2 cells with a non-cytotoxic concentration of SFE significantly reduced RSV replication, RSV-induced cell death, RSV gene transcription, RSV protein synthesis, and syncytium formation. Moreover, oral inoculation of SFE significantly improved RSV clearance from the lungs of BALB/c mice. Interestingly, the phenolic compounds eicosane, docosane, and tetracosane were identified as active components of SFE. Treatment with a non-cytotoxic concentration of these three components elicited similar antiviral effects against RSV infection as SFE in vitro. Together, these results suggest that SFE and its potential components are a promising natural antiviral agent candidate against RSV infection.

Sign in / Sign up

Export Citation Format

Share Document